STRINGSTRING
surE surE AOB34055.1 AOB34055.1 Dgt Dgt AOB34156.1 AOB34156.1 BBB42_01230 BBB42_01230 AOB37240.1 AOB37240.1 AOB34296.1 AOB34296.1 Ldh Ldh AOB34478.1 AOB34478.1 boxB boxB AOB34546.1 AOB34546.1 AOB34561.1 AOB34561.1 rnhA rnhA AOB34732.1 AOB34732.1 rne rne paaX paaX paaG paaG paaH paaH paaI paaI paaJ paaJ paaD paaD xseB xseB AOB35070.1 AOB35070.1 xseA xseA kynA kynA kynB kynB AOB35434.1 AOB35434.1 AOB37300.1 AOB37300.1 dut dut AOB35574.1 AOB35574.1 pnp pnp rnhB rnhB AOB35836.1 AOB35836.1 Fpr Fpr rdgB rdgB rph rph AOB35857.1 AOB35857.1 AOB35897.1 AOB35897.1 AOB35957.1 AOB35957.1 AOB37332.1 AOB37332.1 AOB36056.1 AOB36056.1 AOB36062.1 AOB36062.1 AOB36217.1 AOB36217.1 AOB36322.1 AOB36322.1 AOB36342.1 AOB36342.1 AOB36378.1 AOB36378.1 AOB37357.1 AOB37357.1 AOB36486.1 AOB36486.1 AOB36487.1 AOB36487.1 hmgA hmgA fahA fahA thpD thpD add add ligK ligK LigJ LigJ AOB36801.1 AOB36801.1 AOB36965.1 AOB36965.1 pcaD pcaD catA catA AOB37047.1 AOB37047.1 kynU kynU AOB37084.1 AOB37084.1 mtnN mtnN AOB37098.1 AOB37098.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
surE5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (252 aa)
AOB34055.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
DgtDeoxyguanosinetriphosphate triphosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the dGTPase family. Type 2 subfamily. (375 aa)
AOB34156.1RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. (441 aa)
BBB42_01230ABC transporter permease; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
AOB37240.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
AOB34296.12-hydroxychromene-2-carboxylate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
LdhLactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH2/MDH2 oxidoreductase family. (352 aa)
AOB34478.1Enamine deaminase RidA; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
boxBbenzoyl-CoA oxygenase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
AOB34546.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
AOB34561.1NADH pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
rnhARibonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (153 aa)
AOB34732.1ferredoxin--NADP(+) reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
rneRibonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1043 aa)
paaXPhenylacetic acid degradation operon negative regulatory protein PaaX; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
paaG1,2-phenylacetyl-CoA epoxidase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
paaH1,2-phenylacetyl-CoA epoxidase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
paaIphenylacetate-CoA oxygenase subunit PaaI; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
paaJphenylacetate-CoA oxygenase subunit PaaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
paaDPhenylacetic acid degradation protein PaaD; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (78 aa)
AOB35070.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH2/MDH2 oxidoreductase family. (93 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (452 aa)
kynATryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (279 aa)
kynBArylformamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. (209 aa)
AOB35434.1Class A beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
AOB37300.15-carboxymethyl-2-hydroxymuconate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
dutEctoine/hydroxyectoine ABC transporter ATP-binding protein EhuA; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (149 aa)
AOB35574.1Fumarylacetoacetate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (721 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (202 aa)
AOB35836.1Reactive intermediate/imine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)
Fprferredoxin--NADP(+) reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
rdgBNon-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (207 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (250 aa)
AOB35857.1YicC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
AOB35897.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
AOB35957.1Allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
AOB37332.1Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
AOB36056.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH2/MDH2 oxidoreductase family. (377 aa)
AOB36062.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
AOB36217.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
AOB36322.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
AOB36342.1ATP-dependent RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. (457 aa)
AOB36378.1Isochorismatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
AOB37357.1ATP-dependent RNA helicase DbpA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. (462 aa)
AOB36486.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (147 aa)
AOB36487.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (129 aa)
hmgALysR family transcriptional regulator; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (432 aa)
fahAFumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
thpDEctoine hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
addAdenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (318 aa)
ligK4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
LigJ4-oxalomesaconate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
AOB36801.12-pyrone-4,6-dicarboxylate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
AOB36965.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
pcaD3-oxoadipate enol-lactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
catACatechol 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
AOB37047.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (412 aa)
AOB37084.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
mtnN5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (263 aa)
AOB37098.1RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. (552 aa)
Your Current Organism:
Bordetella holmesii
NCBI taxonomy Id: 35814
Other names: ATCC 51541, B. holmesii, CCUG 34073, CDC F5101, CDC nonoxidizer group 2 (NO-2), CIP 104394, DSM 13416, LMG 15945, LMG:15945, NCTC 12912
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