STRINGSTRING
AOB34057.1 AOB34057.1 hemB hemB lysA lysA argD argD AOB34113.1 AOB34113.1 gabD gabD AOB34138.1 AOB34138.1 AOB34139.1 AOB34139.1 TouE TouE AOB34141.1 AOB34141.1 AOB34142.1 AOB34142.1 TmoA TmoA gltD gltD AOB34194.1 AOB34194.1 AOB34197.1 AOB34197.1 fghA fghA AOB34228.1 AOB34228.1 AOB34240.1 AOB34240.1 AOB34254.1 AOB34254.1 ThcD ThcD AOB37240.1 AOB37240.1 BBB42_01510 BBB42_01510 AOB34287.1 AOB34287.1 fdxH fdxH AOB34289.1 AOB34289.1 rpe rpe AOB34313.1 AOB34313.1 EchA15 EchA15 AOB34341.1 AOB34341.1 AOB34343.1 AOB34343.1 AOB34349.1 AOB34349.1 BBB42_01885 BBB42_01885 Ldh Ldh AOB34403.1 AOB34403.1 AOB34472.1 AOB34472.1 AOB34476.1 AOB34476.1 AOB34477.1 AOB34477.1 hemL hemL accB accB accC accC gltX gltX bclA bclA glyA glyA serB_1 serB_1 accD accD acs acs itaE itaE eno eno AOB34816.1 AOB34816.1 mdh mdh sdhC sdhC sdhD sdhD sdhA sdhA AOB34832.1 AOB34832.1 gltA gltA phnX phnX AOB34845.1 AOB34845.1 mdeB mdeB sucA sucA sucB sucB lpdA_1 lpdA_1 phbB_1 phbB_1 AOB34885.1 AOB34885.1 serC serC AOB34922.1 AOB34922.1 cysD cysD cysN cysN paaG paaG paaH paaH paaI paaI paaJ paaJ paaK paaK paaB paaB rpiA rpiA AOB34980.1 AOB34980.1 AOB35003.1 AOB35003.1 thrC thrC fbp fbp glcD glcD AOB35015.1 AOB35015.1 glcF glcF argD-2 argD-2 AOB35082.1 AOB35082.1 AOB35083.1 AOB35083.1 pcaF pcaF AOB35166.1 AOB35166.1 AOB35171.1 AOB35171.1 AOB35172.1 AOB35172.1 AOB35174.1 AOB35174.1 AOB35175.1 AOB35175.1 AOB35178.1 AOB35178.1 gabD-2 gabD-2 gabT gabT atzF atzF AOB35225.1 AOB35225.1 fdsB fdsB fdsG fdsG AOB35245.1 AOB35245.1 maiA maiA AceA AceA cobA cobA AOB35354.1 AOB35354.1 tkt tkt gap gap pgk pgk ackA ackA fba fba AOB35392.1 AOB35392.1 tal tal AOB35411.1 AOB35411.1 sucC sucC sucD sucD hemC hemC hemD hemD AOB35460.1 AOB35460.1 AOB37300.1 AOB37300.1 thrB thrB asd asd dapE dapE dapD dapD dapC dapC pdxB_4 pdxB_4 AOB35574.1 AOB35574.1 lpdA_2 lpdA_2 aceF aceF aceE aceE folD folD BBB42_09060 BBB42_09060 phbB_2 phbB_2 gdhA gdhA ppsA ppsA AOB35769.1 AOB35769.1 AOB35880.1 AOB35880.1 AOB35895.1 AOB35895.1 AOB35897.1 AOB35897.1 pckG pckG AOB35975.1 AOB35975.1 AOB35993.1 AOB35993.1 AOB35994.1 AOB35994.1 AOB36022.1 AOB36022.1 AOB36049.1 AOB36049.1 Sad Sad pdxB_3 pdxB_3 BBB42_11630 BBB42_11630 AOB36137.1 AOB36137.1 AOB36138.1 AOB36138.1 AOB36165.1 AOB36165.1 accA accA AOB36185.1 AOB36185.1 dapA dapA AOB36235.1 AOB36235.1 tpiA tpiA AOB36257.1 AOB36257.1 icd icd dapB dapB acnA_1 acnA_1 AOB36322.1 AOB36322.1 AOB36393.1 AOB36393.1 AOB36401.1 AOB36401.1 tftE tftE AOB37359.1 AOB37359.1 prs prs hmgA hmgA fahA fahA algC algC pgi pgi AOB36552.1 AOB36552.1 AOB36563.1 AOB36563.1 AOB36578.1 AOB36578.1 AOB36579.1 AOB36579.1 serB_2 serB_2 thpD thpD ectC ectC ectB ectB ectA ectA AOB36717.1 AOB36717.1 AOB36748.1 AOB36748.1 acnB acnB acnA_2 acnA_2 ligK ligK LigJ LigJ AOB36799.1 AOB36799.1 AOB36801.1 AOB36801.1 MdlB MdlB AOB36884.1 AOB36884.1 pdxH pdxH fumC fumC AOB36926.1 AOB36926.1 EchA1 EchA1 pyk pyk AOB36944.1 AOB36944.1 AOB36960.1 AOB36960.1 pcaD pcaD catC catC pcaJ pcaJ AOB36974.1 AOB36974.1 ppc ppc AOB36982.1 AOB36982.1 ubiX ubiX hemA hemA CatB CatB catA catA AOB37006.1 AOB37006.1 gpmA gpmA gabD-3 gabD-3 AOB37084.1 AOB37084.1 metF metF dapF dapF AOB37165.1 AOB37165.1 glcB glcB AOB37191.1 AOB37191.1 AOB37220.1 AOB37220.1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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AOB34057.1NAD-dependent succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
hemBDelta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (338 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (429 aa)
argDAcetylornithine transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (396 aa)
AOB34113.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
gabDSuccinate-semialdehyde dehydrogenase (NADP(+)); Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
AOB34138.1ferredoxin-NAD reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
AOB34139.1(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa)
TouEToluene hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
AOB34141.1Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (106 aa)
AOB34142.1Toluene monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa)
TmoAToluene monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
AOB34194.1Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1579 aa)
AOB34197.1S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
fghAS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (279 aa)
AOB34228.1L-rhamnonate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (390 aa)
AOB34240.1Acylphosphatase; Catalyzes the hydrolysis of acylphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
AOB34254.14-carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
ThcDFerredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
AOB37240.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
BBB42_01510Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
AOB34287.1Formate dehydrogenase-N subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (809 aa)
fdxHFormate dehydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
AOB34289.1Formate dehydrogenase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
rpeRibulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (241 aa)
AOB34313.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
EchA15enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (277 aa)
AOB34341.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
AOB34343.13-hydroxyacyl-CoA dehydrogenase; Converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
AOB34349.1Sulfolactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH2/MDH2 oxidoreductase family. (335 aa)
BBB42_01885Hypothetical protein; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (445 aa)
LdhLactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH2/MDH2 oxidoreductase family. (352 aa)
AOB34403.1D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (399 aa)
AOB34472.1Catalyzes the conversion of salicylyl-CoA to gentisyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (782 aa)
AOB34476.12-aminobenzoate-CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (550 aa)
AOB34477.14-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
accBacetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (148 aa)
accCacetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
gltXTransporter; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (468 aa)
bclA4-hydroxybenzoate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (416 aa)
serB_1Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (292 aa)
acsacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (659 aa)
itaEPermease; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
enoHypothetical protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
AOB34816.1AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (555 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
sdhCSuccinate dehydrogenase, cytochrome b556 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
sdhDSuccinate dehydrogenase, hydrophobic membrane anchor protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (127 aa)
sdhASuccinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (592 aa)
AOB34832.1Succinate dehydrogenase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa)
gltACitrate (Si)-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (433 aa)
phnXPhosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family. (154 aa)
AOB34845.1Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (760 aa)
mdeBPyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (885 aa)
sucA2-oxoglutarate dehydrogenase E1 component; Derived by automated computational analysis using gene prediction method: Protein Homology. (956 aa)
sucBDihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (407 aa)
lpdA_1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
phbB_1beta-ketoacyl-ACP reductase; Catalyzes the formation of 3-hydroxybutyryl-CoA from acetoacetyl-CoA in polyhydroxyalkanoate synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa)
AOB34885.1NAD-dependent succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
serCPhosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (376 aa)
AOB34922.1Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. (242 aa)
cysDSulfate adenylyltransferase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
cysNSulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (435 aa)
paaG1,2-phenylacetyl-CoA epoxidase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
paaH1,2-phenylacetyl-CoA epoxidase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
paaIphenylacetate-CoA oxygenase subunit PaaI; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
paaJphenylacetate-CoA oxygenase subunit PaaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
paaKPhenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
paaB2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
rpiAacyl-CoA dehydrogenase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (224 aa)
AOB34980.13-mercaptopyruvate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
AOB35003.1Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
thrCThreonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
fbpFructose-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. (339 aa)
glcDGlycolate oxidase subunit GlcD; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
AOB35015.1Glycolate oxidase subunit GlcE; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
glcFGlycolate oxidase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
argD-2Acetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (393 aa)
AOB35082.1GMC family oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (593 aa)
AOB35083.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
pcaF3-oxoadipyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
AOB35166.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (175 aa)
AOB35171.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
AOB35172.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (794 aa)
AOB35174.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (652 aa)
AOB35175.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
AOB35178.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
gabD-2Succinate-semialdehyde dehydrogenase (NADP(+)); Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa)
gabT4-aminobutyrate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (421 aa)
atzFAllophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (603 aa)
AOB35225.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
fdsBFormate dehydrogenase subunit alpha; Frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (519 aa)
fdsGFormate dehydrogenase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
AOB35245.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
maiAMaleylacetoacetate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
AceAIsocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
cobAuroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (463 aa)
AOB35354.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (762 aa)
tktTransketolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family. (679 aa)
gapType I glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (397 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa)
fbaFructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
AOB35392.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (318 aa)
AOB35411.1Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
sucCsuccinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (312 aa)
hemDuroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (259 aa)
AOB35460.1Heme biosynthesis operon protein HemX; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
AOB37300.15-carboxymethyl-2-hydroxymuconate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
thrBHomoserine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudomonas-type ThrB family. (322 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (376 aa)
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (377 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transferase hexapeptide repeat family. (273 aa)
dapCSuccinyldiaminopimelate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
pdxB_43-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
AOB35574.1Fumarylacetoacetate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
lpdA_2Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (591 aa)
aceFDihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (554 aa)
aceEPyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (903 aa)
folDBifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
BBB42_09060tRNA-Ser; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
phbB_2beta-ketoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa)
gdhAGlutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (429 aa)
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (788 aa)
AOB35769.1Isocitrate dehydrogenase, NADP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (742 aa)
AOB35880.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
AOB35895.1Carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
AOB35897.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (618 aa)
AOB35975.1Phosphonopyruvate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
AOB35993.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
AOB35994.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (480 aa)
AOB36022.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)
AOB36049.14-carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
SadSuccinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
pdxB_3D-3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa)
BBB42_11630Amine oxidase; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
AOB36137.1Glyoxylate/hydroxypyruvate reductase A; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
AOB36138.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (457 aa)
AOB36165.1Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (419 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (321 aa)
AOB36185.1Amidase; Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (301 aa)
AOB36235.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
AOB36257.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
icdNADP-dependent isocitrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (263 aa)
acnA_1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (891 aa)
AOB36322.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
AOB36393.1Zinc-binding dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
AOB36401.1Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
tftEMaleylacetate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
AOB37359.15-carboxymethyl-2-hydroxymuconate delta-isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa)
hmgALysR family transcriptional regulator; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (432 aa)
fahAFumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
algCPhosphoglucomutase; Catalyzes the interconversion of alpha-D-mannose 1-phosphate to alpha-D-mannose 6-phosphate and alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (525 aa)
AOB36552.1Gamma carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
AOB36563.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
AOB36578.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
AOB36579.16-carboxyhexanoate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (710 aa)
serB_2Transposase; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
thpDEctoine hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
ectCL-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (132 aa)
ectBDiaminobutyrate--2-oxoglutarate transaminase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (434 aa)
ectADiaminobutyrate acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. (190 aa)
AOB36717.1Carboxymethylenebutenolidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
AOB36748.1acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
acnBBifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family. (863 aa)
acnA_2Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (901 aa)
ligK4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
LigJ4-oxalomesaconate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
AOB36799.1PrpF protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
AOB36801.12-pyrone-4,6-dicarboxylate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
MdlBAlpha-hydroxy-acid oxidizing enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
AOB36884.1Cupin; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (210 aa)
fumCHypothetical protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)
AOB36926.1Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa)
EchA1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa)
pykPyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (480 aa)
AOB36944.1Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family. (380 aa)
AOB36960.1Sulfite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (502 aa)
pcaD3-oxoadipate enol-lactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
catCMuconolactone delta-isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the muconolactone Delta-isomerase family. (91 aa)
pcaJ3-oxoadipate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
AOB36974.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (948 aa)
AOB36982.1Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (301 aa)
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (188 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (424 aa)
CatBMuconate cycloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (381 aa)
catACatechol 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
AOB37006.11,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa)
gabD-3Succinate-semialdehyde dehydrogenase (NADP(+)); Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (489 aa)
AOB37084.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
metFMethylenetetrahydrofolate reductase [NAD(P)H]; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (280 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (298 aa)
AOB37165.1Dihydrodipicolinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (723 aa)
AOB37191.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (475 aa)
AOB37220.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (764 aa)
Your Current Organism:
Bordetella holmesii
NCBI taxonomy Id: 35814
Other names: ATCC 51541, B. holmesii, CCUG 34073, CDC F5101, CDC nonoxidizer group 2 (NO-2), CIP 104394, DSM 13416, LMG 15945, LMG:15945, NCTC 12912
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