STRINGSTRING
AFU47668.1 AFU47668.1 mpl mpl AFU44516.1 AFU44516.1 ddl ddl murC murC murD murD murF murF murE murE atpA atpA atpG atpG atpD atpD atpC atpC AFU44159.1 AFU44159.1 AFU44177.1 AFU44177.1 AFU44254.1 AFU44254.1 AFU44262.1 AFU44262.1 AFU44268.1 AFU44268.1 purT purT glyQ glyQ glyS glyS AFU44362.1 AFU44362.1 AFU44388.1 AFU44388.1 AFU44392.1 AFU44392.1 AFU44402.1 AFU44402.1 rtcA rtcA AFU48436.1 AFU48436.1 sucC sucC AFU44441.1 AFU44441.1 AFU48366.1 AFU48366.1 sucD sucD AFU48208.1 AFU48208.1 purK purK purC purC leuS leuS AFU48169.1 AFU48169.1 gshB gshB argS argS AFU48123.1 AFU48123.1 AFU47985.1 AFU47985.1 AFU47943.1 AFU47943.1 AFU47911.1 AFU47911.1 AFU47901.1 AFU47901.1 AFU47851.1 AFU47851.1 AFU47804.1 AFU47804.1 AFU47803.1 AFU47803.1 AFU47799.1 AFU47799.1 tyrS tyrS AFU47722.1 AFU47722.1 AFU47717.1 AFU47717.1 AFU47708.1 AFU47708.1 AFU47701.1 AFU47701.1 AFU47700.1 AFU47700.1 AFU47676.1 AFU47676.1 AFU47502.1 AFU47502.1 panC panC bioD bioD metG metG purM purM valS valS AFU47206.1 AFU47206.1 gshA gshA glnS glnS cysS cysS accA accA tilS tilS AFU46943.1 AFU46943.1 acsA acsA AFU46813.1 AFU46813.1 AFU46793.1 AFU46793.1 AFU46675.1 AFU46675.1 guaA guaA AFU46594.1 AFU46594.1 AFU46564.1 AFU46564.1 thrS thrS pheS pheS pheT pheT argG argG AFU46457.1 AFU46457.1 gltX gltX pncB-2 pncB-2 AFU46382.1 AFU46382.1 purD purD ligA ligA AFU46122.1 AFU46122.1 AFU46118.1 AFU46118.1 AFU46117.1 AFU46117.1 AFU46058.1 AFU46058.1 AFU46057.1 AFU46057.1 prpE prpE gluQ gluQ alaS alaS AFU45847.1 AFU45847.1 purL purL nadE-3 nadE-3 carB carB carA carA AFU45521.1 AFU45521.1 AFU45420.1 AFU45420.1 AFU45401.1 AFU45401.1 purA purA hisZ hisZ hisS hisS AFU47507.1 AFU47507.1 AFU45361.1 AFU45361.1 AFU45319.1 AFU45319.1 AFU45298.1 AFU45298.1 pyrG pyrG accD accD AFU45176.1 AFU45176.1 lysS lysS ileS ileS AFU45006.1 AFU45006.1 trpS trpS nadE nadE serS serS aspS aspS proS proS pncB pncB atpH atpH atpF atpF atpE atpE atpB atpB gatC gatC gatA gatA gatB gatB AFU44030.1 AFU44030.1 AFU43982.1 AFU43982.1 AFU43947.1 AFU43947.1 AFU43931.1 AFU43931.1 queC queC AFU43884.1 AFU43884.1 AFU43882.1 AFU43882.1 AFU43846.1 AFU43846.1 AFU43795.1 AFU43795.1 AFU43738.1 AFU43738.1 AFU47515.1 AFU47515.1 AFU47667.1 AFU47667.1 nadE-2 nadE-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFU47668.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (151 aa)
mplUDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (473 aa)
AFU44516.1AMP-dependent synthetase/ligase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (521 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (329 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (477 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (621 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (488 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (504 aa)
atpAF0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (517 aa)
atpGF0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (288 aa)
atpDF0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (468 aa)
atpCF0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (138 aa)
AFU44159.1UBA/THIF-type NAD/FAD binding protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. (385 aa)
AFU44177.1COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (536 aa)
AFU44254.12-aminobenzoate-CoA ligase; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (555 aa)
AFU44262.1Putative phenylacetate-CoA ligase; COG1541 Coenzyme F390 synthetase. (415 aa)
AFU44268.1AMP-dependent synthetase and ligase; COG1022 Long-chain acyl-CoA synthetases (AMP-forming). (648 aa)
purTPhosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (400 aa)
glyQCOG0752 Glycyl-tRNA synthetase, alpha subunit. (301 aa)
glySCOG0751 Glycyl-tRNA synthetase, beta subunit. (713 aa)
AFU44362.1Hypothetical protein; COG0439 Biotin carboxylase. (370 aa)
AFU44388.1COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (537 aa)
AFU44392.1Carbamoyl-phosphate synthase L chain, ATP-binding protein; COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit. (644 aa)
AFU44402.1AMP-dependent synthetase and ligase; COG1022 Long-chain acyl-CoA synthetases (AMP-forming). (618 aa)
rtcARNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. (357 aa)
AFU48436.1COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (546 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
AFU44441.1Hypothetical protein. (405 aa)
AFU48366.1COG0340 Biotin-(acetyl-CoA carboxylase) ligase. (286 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (298 aa)
AFU48208.1COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (559 aa)
purKPhosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (390 aa)
purCCOG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. (306 aa)
leuSCOG0495 Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (897 aa)
AFU48169.1Glutamate--cysteine ligase. (431 aa)
gshBCOG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family. (318 aa)
argSCOG0018 Arginyl-tRNA synthetase. (569 aa)
AFU48123.1Gamma-glutamyl:cysteine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (375 aa)
AFU47985.1Threonyl/alanyl tRNA synthetase, SAD; COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain. (250 aa)
AFU47943.1COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (525 aa)
AFU47911.1COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (190 aa)
AFU47901.1COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (560 aa)
AFU47851.1Flagellar protein export ATPase FliI; COG1157 Flagellar biosynthesis/type III secretory pathway ATPase. (468 aa)
AFU47804.1AMP-binding domain protein; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (576 aa)
AFU47803.1COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (535 aa)
AFU47799.1COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit. (675 aa)
tyrStyrosyl-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (410 aa)
AFU47722.1benzoate-CoA ligase family protein; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (517 aa)
AFU47717.1feruloyl-CoA synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (599 aa)
AFU47708.1COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (503 aa)
AFU47701.1Cyanophycin synthetase; COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes. (859 aa)
AFU47700.1Cyanophycin synthetase; COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes. (735 aa)
AFU47676.1Hypothetical protein. (112 aa)
AFU47502.1Hypothetical protein. (881 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (279 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (223 aa)
metGmethionyl-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (691 aa)
purMCOG0150 Phosphoribosylaminoimidazole (AIR) synthetase. (349 aa)
valSvalyl-tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (965 aa)
AFU47206.1GatB/YqeY domain-containing protein. (148 aa)
gshAGlutamate--cysteine ligase; COG2918 Gamma-glutamylcysteine synthetase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. (508 aa)
glnSCOG0008 Glutamyl- and glutaminyl-tRNA synthetases. (611 aa)
cysSCOG0215 Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (460 aa)
accAacetyl-CoA carboxylase, carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (316 aa)
AFU46943.1COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (515 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (664 aa)
AFU46813.1malonyl-CoA synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (524 aa)
AFU46793.1CobB/CobQ domain-containing protein glutamine amidotransferase; COG1797 Cobyrinic acid a,c-diamide synthase. (464 aa)
AFU46675.1DNA ligase; COG1793 ATP-dependent DNA ligase. (287 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (538 aa)
AFU46594.1COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (555 aa)
AFU46564.1Phosphoesterase HXTX; COG1514 2'-5' RNA ligase. (195 aa)
thrSthreonyl-tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (639 aa)
pheSCOG0016 Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (350 aa)
pheTphenylalanyl-tRNA ligase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (815 aa)
argGCOG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (445 aa)
AFU46457.1FolC bifunctional protein; COG0285 Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (441 aa)
gltXglutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (473 aa)
pncB-2Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (406 aa)
AFU46382.1COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (547 aa)
purDCOG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. (426 aa)
ligADNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (695 aa)
AFU46122.1AMP-dependent synthetase and ligase; COG1022 Long-chain acyl-CoA synthetases (AMP-forming). (618 aa)
AFU46118.1COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (510 aa)
AFU46117.1Carbamoyl-phosphate synthase L chain, ATP-binding protein; COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit. (682 aa)
AFU46058.15-oxoprolinase; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit. (694 aa)
AFU46057.15-oxoprolinase; COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit. (566 aa)
prpECOG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (633 aa)
gluQglutamate--tRNA ligase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (318 aa)
alaSalanyl-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (875 aa)
AFU45847.1UBA/THIF-type NAD/FAD-binding protein; COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1. (276 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1335 aa)
nadE-3NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (552 aa)
carBCOG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. (1081 aa)
carACOG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. (387 aa)
AFU45521.1Amidase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Belongs to the amidase family. (451 aa)
AFU45420.1Hypothetical protein. (98 aa)
AFU45401.1COG0174 Glutamine synthetase. (471 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (458 aa)
hisZClass II tRNA synthetase; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (382 aa)
hisSCOG0124 Histidyl-tRNA synthetase. (440 aa)
AFU47507.1Hypothetical protein. (510 aa)
AFU45361.1COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (548 aa)
AFU45319.1Hypothetical protein. (504 aa)
AFU45298.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (407 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (552 aa)
accDacetyl-CoA carboxylase, carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (290 aa)
AFU45176.1COG0367 Asparagine synthase (glutamine-hydrolyzing). (628 aa)
lysSCOG1190 Lysyl-tRNA synthetase (class II); Belongs to the class-II aminoacyl-tRNA synthetase family. (514 aa)
ileSisoleucyl-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (961 aa)
AFU45006.1Von Willebrand factor type A; COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain. (348 aa)
trpStryptophanyl-tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (434 aa)
nadENAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (277 aa)
serSseryl-tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (438 aa)
aspSaspartyl-tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (605 aa)
proSprolyl-tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacyla [...] (580 aa)
pncBNicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (399 aa)
atpHF0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (180 aa)
atpFF0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (156 aa)
atpEF0F1 ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (89 aa)
atpBF0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (292 aa)
gatCglutamyl-tRNA(Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (99 aa)
gatAaspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (497 aa)
gatBglutamyl-tRNA(Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (482 aa)
AFU44030.1COG3307 Lipid A core - O-antigen ligase and related enzymes. (428 aa)
AFU43982.1feruloyl-CoA synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (625 aa)
AFU43947.1COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (563 aa)
AFU43931.1COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (562 aa)
queCexsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (236 aa)
AFU43884.1COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (649 aa)
AFU43882.1COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (699 aa)
AFU43846.1COG1793 ATP-dependent DNA ligase. (565 aa)
AFU43795.1long-chain-fatty-acid--CoA ligase; COG1022 Long-chain acyl-CoA synthetases (AMP-forming). (599 aa)
AFU43738.1COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (546 aa)
AFU47515.1UBA/THIF-type NAD/FAD-binding protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2. (249 aa)
AFU47667.1acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
nadE-2NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (566 aa)
Your Current Organism:
Acidovorax sp. KKS102
NCBI taxonomy Id: 358220
Other names: A. sp. KKS102
Server load: low (24%) [HD]