STRINGSTRING
AFU44388.1 AFU44388.1 AFU44362.1 AFU44362.1 AFU44326.1 AFU44326.1 AFU44325.1 AFU44325.1 lipA lipA AFU44023.1 AFU44023.1 AFU47667.1 AFU47667.1 bioF bioF bioD bioD AFU47488.1 AFU47488.1 panD panD AFU47093.1 AFU47093.1 accA accA AFU46816.1 AFU46816.1 AFU46674.1 AFU46674.1 AFU45769.1 AFU45769.1 fabZ fabZ AFU45231.1 AFU45231.1 accD accD acpS acpS AFU45151.1 AFU45151.1 acpP acpP AFU45148.1 AFU45148.1 fabH fabH plsX plsX AFU46061.1 AFU46061.1 AFU47668.1 AFU47668.1 AFU47588.1 AFU47588.1 AFU47546.1 AFU47546.1 panC panC panB panB AFU47706.1 AFU47706.1 AFU47747.1 AFU47747.1 AFU47803.1 AFU47803.1 AFU48113.1 AFU48113.1 AFU48402.1 AFU48402.1 AFU48419.1 AFU48419.1 AFU46197.1 AFU46197.1 AFU46178.1 AFU46178.1 AFU46118.1 AFU46118.1 bioB bioB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFU44388.1COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (537 aa)
AFU44362.1Hypothetical protein; COG0439 Biotin carboxylase. (370 aa)
AFU44326.1Beta-ketoacyl synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (407 aa)
AFU44325.13-hydroxydecanoyl-(acyl carrier protein) dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (173 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (326 aa)
AFU44023.12-dehydropantoate 2-reductase; COG1893 Ketopantoate reductase. (325 aa)
AFU47667.1acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
bioF8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (406 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (223 aa)
AFU47488.1Aminotransferase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (441 aa)
panDAspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (126 aa)
AFU47093.1PIG3 family NAD(P)H quinone oxidoreductase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (349 aa)
accAacetyl-CoA carboxylase, carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa)
AFU46816.1malonyl-CoA decarboxylase. (495 aa)
AFU46674.1Short-chain dehydrogenase/reductase sdr; COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH). (266 aa)
AFU45769.1Alcohol dehydrogenase GroES domain-containing protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (336 aa)
fabZ(3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa)
AFU45231.1NAD(P)H quinone oxidoreductase, PIG3 family protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (328 aa)
accDacetyl-CoA carboxylase, carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (290 aa)
acpSHolo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (135 aa)
AFU45151.13-oxoacyl-ACP synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (414 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (79 aa)
AFU45148.1COG0331 (acyl-carrier-protein) S-malonyltransferase. (316 aa)
fabH3-oxoacyl-(acyl carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (325 aa)
plsXPhosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (350 aa)
AFU46061.1Isocitrate lyase and phosphorylmutase; COG2513 PEP phosphonomutase and related enzymes. (287 aa)
AFU47668.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (151 aa)
AFU47588.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (330 aa)
AFU47546.1Biotin synthesis protein BioC; COG0500 SAM-dependent methyltransferases. (300 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (279 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (293 aa)
AFU47706.1Carboxyvinyl-carboxyphosphonate phosphorylmutase; COG2513 PEP phosphonomutase and related enzymes. (302 aa)
AFU47747.13-oxoacyl-ACP synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (421 aa)
AFU47803.1COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (535 aa)
AFU48113.1Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (236 aa)
AFU48402.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (312 aa)
AFU48419.1Beta alanine--pyruvate transaminase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
AFU46197.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (321 aa)
AFU46178.1Methylisocitrate lyase; COG2513 PEP phosphonomutase and related enzymes. (290 aa)
AFU46118.1COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (510 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (347 aa)
Your Current Organism:
Acidovorax sp. KKS102
NCBI taxonomy Id: 358220
Other names: A. sp. KKS102
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