STRINGSTRING
AFU44213.1 AFU44213.1 AFU44290.1 AFU44290.1 AFU44397.1 AFU44397.1 AFU44398.1 AFU44398.1 AFU44407.1 AFU44407.1 AFU44509.1 AFU44509.1 AFU45109.1 AFU45109.1 accD accD AFU45367.1 AFU45367.1 AFU45884.1 AFU45884.1 AFU45950.1 AFU45950.1 AFU45985.1 AFU45985.1 prpE prpE AFU46117.1 AFU46117.1 AFU46118.1 AFU46118.1 AFU46120.1 AFU46120.1 AFU46158.1 AFU46158.1 AFU46175.1 AFU46175.1 AFU46176.1 AFU46176.1 AFU46177.1 AFU46177.1 AFU46214.1 AFU46214.1 AFU46267.1 AFU46267.1 AFU46375.1 AFU46375.1 AFU46596.1 AFU46596.1 AFU46814.1 AFU46814.1 AFU46816.1 AFU46816.1 acsA acsA accA accA AFU47074.1 AFU47074.1 AFU47647.1 AFU47647.1 AFU47667.1 AFU47667.1 AFU47668.1 AFU47668.1 AFU47709.1 AFU47709.1 AFU47821.1 AFU47821.1 AFU47824.1 AFU47824.1 AFU47976.1 AFU47976.1 AFU48160.1 AFU48160.1 sucD sucD sucC sucC AFU48419.1 AFU48419.1 AFU48421.1 AFU48421.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFU44213.1Iron-containing alcohol dehydrogenase; COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family. (387 aa)
AFU44290.1COG1024 Enoyl-CoA hydratase/carnithine racemase. (272 aa)
AFU44397.13-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
AFU44398.1COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
AFU44407.1COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (265 aa)
AFU44509.1COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
AFU45109.1Hypothetical protein; COG1803 Methylglyoxal synthase. (289 aa)
accDacetyl-CoA carboxylase, carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (290 aa)
AFU45367.1Zinc-containing alcohol dehydrogenase superfamily protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (327 aa)
AFU45884.1COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (475 aa)
AFU45950.1COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (471 aa)
AFU45985.1COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (616 aa)
prpECOG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. (633 aa)
AFU46117.1Carbamoyl-phosphate synthase L chain, ATP-binding protein; COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit. (682 aa)
AFU46118.1COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (510 aa)
AFU46120.1COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. (722 aa)
AFU46158.1COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
AFU46175.1COG0372 Citrate synthase; Belongs to the citrate synthase family. (387 aa)
AFU46176.12-methylisocitrate dehydratase, Fe/S-dependent; COG1048 Aconitase A. (878 aa)
AFU46177.1AcnD-accessory protein PrpF; COG2828 Uncharacterized protein conserved in bacteria. (402 aa)
AFU46214.1COG1012 NAD-dependent aldehyde dehydrogenases. (507 aa)
AFU46267.1COG1024 Enoyl-CoA hydratase/carnithine racemase. (280 aa)
AFU46375.1COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
AFU46596.1COG1024 Enoyl-CoA hydratase/carnithine racemase. (261 aa)
AFU46814.1COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (267 aa)
AFU46816.1malonyl-CoA decarboxylase. (495 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (664 aa)
accAacetyl-CoA carboxylase, carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa)
AFU47074.1Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; COG1049 Aconitase B; Belongs to the aconitase/IPM isomerase family. (863 aa)
AFU47647.1COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (259 aa)
AFU47667.1acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
AFU47668.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (151 aa)
AFU47709.1COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
AFU47821.1COG1960 Acyl-CoA dehydrogenases. (376 aa)
AFU47824.1COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
AFU47976.1COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
AFU48160.1Coenzyme A transferase; COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase. (641 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (298 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
AFU48419.1Beta alanine--pyruvate transaminase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
AFU48421.1COG1012 NAD-dependent aldehyde dehydrogenases. (505 aa)
Your Current Organism:
Acidovorax sp. KKS102
NCBI taxonomy Id: 358220
Other names: A. sp. KKS102
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