STRINGSTRING
APW96250.1 APW96250.1 APW96275.1 APW96275.1 trpA trpA trpB trpB trpC trpC APW96313.1 APW96313.1 fhs fhs mfnA mfnA APW96341.1 APW96341.1 pyrG pyrG guaAB guaAB carA carA APW96449.1 APW96449.1 APW96450.1 APW96450.1 APW96451.1 APW96451.1 lysA lysA dapD dapD dapB dapB dapA dapA APW96473.1 APW96473.1 aroE aroE APW96489.1 APW96489.1 APW96490.1 APW96490.1 APW96491.1 APW96491.1 APW96504.1 APW96504.1 purQ purQ purS purS purC purC APW96571.1 APW96571.1 tmk tmk APW96589.1 APW96589.1 APW96634.1 APW96634.1 APW96651.1 APW96651.1 APW96724.1 APW96724.1 APW96878.1 APW96878.1 APW96880.1 APW96880.1 APW96881.1 APW96881.1 APW96899.1 APW96899.1 APW99994.1 APW99994.1 APW96906.1 APW96906.1 APW97008.1 APW97008.1 APW97015.1 APW97015.1 lysK lysK lysJ lysJ lysZ lysZ argC argC APW97024.1 APW97024.1 APW97025.1 APW97025.1 argH argH argG argG APW97035.1 APW97035.1 APW97043.1 APW97043.1 purO purO APW97072.1 APW97072.1 APW97099.1 APW97099.1 ahcY ahcY hisG hisG hisA hisA hisI hisI APW97266.1 APW97266.1 metXA metXA APW97270.1 APW97270.1 hisB hisB upp upp APW97299.1 APW97299.1 APW97318.1 APW97318.1 solA solA APW97424.1 APW97424.1 APW97442.1 APW97442.1 APW97471.1 APW97471.1 APW97510.1 APW97510.1 hisE hisE APW97557.1 APW97557.1 pyrH pyrH APW97588.1 APW97588.1 hisH hisH APW97613.1 APW97613.1 APW97629.1 APW97629.1 APW97651.1 APW97651.1 APW97673.1 APW97673.1 thrB thrB APW97757.1 APW97757.1 APW97775.1 APW97775.1 APW97805.1 APW97805.1 speE speE APW97888.1 APW97888.1 APW97891.1 APW97891.1 leuC leuC ilvC ilvC APW97895.1 APW97895.1 APW97896.1 APW97896.1 APW97897.1 APW97897.1 ilvE ilvE pyrE pyrE APW97951.1 APW97951.1 APW98017.1 APW98017.1 APW98048.1 APW98048.1 APW98089.1 APW98089.1 APW98090.1 APW98090.1 APW98092.1 APW98092.1 APW98099.1 APW98099.1 APW98106.1 APW98106.1 purF purF APW98139.1 APW98139.1 APW98146.1 APW98146.1 APW98148.1 APW98148.1 APW98167.1 APW98167.1 APW98188.1 APW98188.1 APW98189.1 APW98189.1 glmS-2 glmS-2 gcvH gcvH gcvT gcvT APW98248.1 APW98248.1 APW98294.1 APW98294.1 APW98295.1 APW98295.1 APW98394.1 APW98394.1 APW98450.1 APW98450.1 APW98474.1 APW98474.1 pyrI pyrI pyrB pyrB APW98511.1 APW98511.1 APW98542.1 APW98542.1 APW98548.1 APW98548.1 APW98550.1 APW98550.1 ilvD ilvD hisC hisC APW98610.1 APW98610.1 guaB guaB APW98661.1 APW98661.1 APW98667.1 APW98667.1 purM purM pyrF pyrF glmS-3 glmS-3 trpD trpD trpF trpF trpE trpE APW98929.1 APW98929.1 APW98931.1 APW98931.1 APW98937.1 APW98937.1 APW98950.1 APW98950.1 hisD hisD APW98959.1 APW98959.1 cysS cysS hisF hisF APW99078.1 APW99078.1 purL purL APW99091.1 APW99091.1 hutI hutI APW99093.1 APW99093.1 hutU hutU APW99095.1 APW99095.1 adk adk gshA gshA dys dys APW99161.1 APW99161.1 glyA glyA folD folD APW99230.1 APW99230.1 purD purD APW99244.1 APW99244.1 APW99245.1 APW99245.1 APW99297.1 APW99297.1 APW99299.1 APW99299.1 dcd dcd surE surE APW99422.1 APW99422.1 aroA-2 aroA-2 APW99444.1 APW99444.1 guaAA guaAA udk udk APW99488.1 APW99488.1 APW99522.1 APW99522.1 carB carB C445_05413 C445_05413 aroK aroK APW99591.1 APW99591.1 aroC aroC APW99648.1 APW99648.1 katG katG APW99725.1 APW99725.1 APW99726.1 APW99726.1 APW99743.1 APW99743.1 APW99782.1 APW99782.1 APW99785.1 APW99785.1 APW99796.1 APW99796.1 APW99854.1 APW99854.1 surE-2 surE-2 purA purA purE purE purK purK APW99937.1 APW99937.1 APW99945.1 APW99945.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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APW96250.1Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1517 aa)
APW96275.1Tryptophan synthase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (308 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (449 aa)
trpCIndole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (276 aa)
APW96313.1Sarcosine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
fhsFormate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. (571 aa)
mfnATyrosine decarboxylase MfnA; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily. (381 aa)
APW96341.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (783 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (563 aa)
guaABGMP synthase; Catalyzes the synthesis of GMP from XMP. (305 aa)
carACarbamoyl-phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (358 aa)
APW96449.1Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
APW96450.1Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (461 aa)
APW96451.1dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (413 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (257 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (312 aa)
APW96473.1N-acyl-L-amino acid amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (268 aa)
APW96489.1Anthranilate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa)
APW96490.1Anthranilate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
APW96491.14-amino-4-deoxychorismate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (290 aa)
APW96504.13-dehydroquinate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (224 aa)
purSPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (83 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (341 aa)
APW96571.1Asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
tmkdTMP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
APW96589.1O-acetyl-L-homoserine sulfhydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
APW96634.1Uridine phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
APW96651.1Bifunctional metallophosphatase/5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (670 aa)
APW96724.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (564 aa)
APW96878.1Na+/H+ antiporter NhaC; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa)
APW96880.1Selenium-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
APW96881.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)
APW96899.1Dihydroorotase; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
APW99994.1Uracil permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
APW96906.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
APW97008.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
APW97015.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (425 aa)
lysKAcetyl-lysine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. (371 aa)
lysJAspartate aminotransferase family protein; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. (384 aa)
lysZAcetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. (290 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (360 aa)
APW97024.1Lysine biosynthesis enzyme LysX; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
APW97025.1Lysine biosynthesis protein LysW; Derived by automated computational analysis using gene prediction method: Protein Homology. (54 aa)
argHArgininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
argGArgininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (424 aa)
APW97035.1Low specificity L-threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
APW97043.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
purOIMP cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP. (198 aa)
APW97072.1Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
APW97099.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (392 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (435 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (287 aa)
hisA1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (126 aa)
APW97266.1Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (399 aa)
APW97270.1O-acetyl-L-homoserine sulfhydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
hisBImidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (225 aa)
APW97299.1Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
APW97318.1Kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa)
solAN-methyltryptophan oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
APW97424.1Deoxyuridine 5'-triphosphate nucleotidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
APW97442.1Pyruvoyl-dependent arginine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
APW97471.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
APW97510.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (451 aa)
hisEphosphoribosyl-ATP diphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
APW97557.1Glycine cleavage system protein T; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (248 aa)
APW97588.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (220 aa)
APW97613.1Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (451 aa)
APW97629.1Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
APW97651.1Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
APW97673.1Non-canonical purine NTP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HAM1 NTPase family. (182 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (293 aa)
APW97757.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
APW97775.1Agmatinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. (289 aa)
APW97805.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (557 aa)
APW97888.1Isocitrate dehydrogenase; Catalyzes the formation of 2-oxoglutarate from isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
APW97891.13-isopropylmalate dehydratase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (474 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (358 aa)
APW97895.1Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
APW97896.1Acetolactate synthase, large subunit, biosynthetic type; Derived by automated computational analysis using gene prediction method: Protein Homology. (599 aa)
APW97897.12-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
ilvEBranched chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (309 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (178 aa)
APW97951.1Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
APW98017.1Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (599 aa)
APW98048.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
APW98089.1Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
APW98090.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
APW98092.1Asparagine synthetase B; Derived by automated computational analysis using gene prediction method: Protein Homology. (631 aa)
APW98099.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
APW98106.1Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (490 aa)
APW98139.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
APW98146.1Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
APW98148.1Agmatinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. (344 aa)
APW98167.1Pyridoxal-5'-phosphate-dependent protein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
APW98188.1Uracil permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
APW98189.1Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (81 aa)
glmS-2Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (600 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (365 aa)
APW98248.1Orotate phosphoribosyltransferase-like protein; Purine/pyrimidine phosphoribosyltransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
APW98294.1Glycine dehydrogenase (aminomethyl-transferring); Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
APW98295.1Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
APW98394.1Citramalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
APW98450.1L-asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
APW98474.1Ornithine carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (295 aa)
pyrIAspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (156 aa)
pyrBAspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
APW98511.12-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa)
APW98542.1NADP-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (751 aa)
APW98548.1Uridine phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
APW98550.1Cytidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
ilvDDihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (578 aa)
hisCPyridoxamine 5-phosphate oxidase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
APW98610.1Adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (177 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (500 aa)
APW98661.1Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
APW98667.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily. (265 aa)
glmS-3Nucleotidyl transferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (604 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (344 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (229 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (576 aa)
APW98929.1Glutamine amidotransferase; TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
APW98931.1Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1044 aa)
APW98937.1Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (559 aa)
APW98950.1Aspartate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (426 aa)
APW98959.1Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
cysScysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
hisFImidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (271 aa)
APW99078.1Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (718 aa)
APW99091.1Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (550 aa)
hutIImidazolonepropionase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (411 aa)
APW99093.1Formimidoylglutamase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. (332 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (596 aa)
APW99095.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (211 aa)
gshACarboxylate--amine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (360 aa)
dysDeoxyhypusine synthase; Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. (327 aa)
APW99161.1Nodulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (301 aa)
APW99230.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)
purDPhosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (449 aa)
APW99244.1Leucine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (353 aa)
APW99245.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
APW99297.1Allantoinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
APW99299.1Dihydroorotate dehydrogenase (quinone); Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
dcdDeoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (198 aa)
surE5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (275 aa)
APW99422.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
aroA-23-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (439 aa)
APW99444.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
guaAAGMP synthase; Catalyzes the synthesis of GMP from XMP. (184 aa)
udkUridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
APW99488.1Guanosine monophosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
APW99522.1Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (451 aa)
carBCarbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1057 aa)
C445_05413VapC toxin family PIN domain ribonuclease; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa)
aroKShikimate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
APW99591.1Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (383 aa)
APW99648.1Xanthine permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
katGCatalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (713 aa)
APW99725.1Adenine phosphoribosyltransferase; May catalyze a purine salvage reaction, the substrate is unknown. (181 aa)
APW99726.1Uracil permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
APW99743.1Zn-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
APW99782.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (425 aa)
APW99785.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (418 aa)
APW99796.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa)
APW99854.1Adenine phosphoribosyltransferase; May catalyze a purine salvage reaction, the substrate is unknown. (188 aa)
surE-25'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (327 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (459 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (215 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (385 aa)
APW99937.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
APW99945.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
Your Current Organism:
Halobiforma lacisalsi
NCBI taxonomy Id: 358396
Other names: H. lacisalsi AJ5, Halobiforma lacisalsi AJ5, Halobiforma lacisalsi str. AJ5, Halobiforma lacisalsi strain AJ5
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