STRINGSTRING
rps10p rps10p tuf-2 tuf-2 rpoP rpoP rpl37ae rpl37ae APW99842.1 APW99842.1 APW99841.1 APW99841.1 rpl44e rpl44e rps27e rps27e eif2a eif2a leuS-2 leuS-2 APW99713.1 APW99713.1 tfe tfe rps15p rps15p rps3ae rps3ae pth pth APW99344.1 APW99344.1 APW99330.1 APW99330.1 APW99285.1 APW99285.1 APW99283.1 APW99283.1 APX00121.1 APX00121.1 tfb-6 tfb-6 APW99267.1 APW99267.1 glmS-5 glmS-5 APW99185.1 APW99185.1 APW99173.1 APW99173.1 APW99166.1 APW99166.1 APW99055.1 APW99055.1 gatC gatC gatA gatA APX00108.1 APX00108.1 rpoL rpoL cysS cysS gatE gatE rps17E rps17E APW98903.1 APW98903.1 APW98901.1 APW98901.1 C445_21026 C445_21026 APW98887.1 APW98887.1 APW98882.1 APW98882.1 tfb-5 tfb-5 glmS-3 glmS-3 APW98822.1 APW98822.1 rpl3p rpl3p rpl4lp rpl4lp rpl23 rpl23 rpl2p rpl2p rps19p rps19p rpl22p rpl22p rps3p rps3p rpl29 rpl29 rps17p rps17p rpl14p rpl14p rpl24p rpl24p rps4e rps4e rpl5p rpl5p rps14P rps14P rps8p rps8p rpl6p rpl6p rpl32e rpl32e rpl19e rpl19e rpl18p rpl18p rps5p rps5p rpl30p rpl30p rpl15p rpl15p rpl11p rpl11p rpl1P rpl1P rplP0 rplP0 rpl12p rpl12p APW98622.1 APW98622.1 lig lig APW98588.1 APW98588.1 dbh dbh APW98574.1 APW98574.1 APW98544.1 APW98544.1 rps8e rps8e argS argS APW98450.1 APW98450.1 APW98424.1 APW98424.1 rpl24e rpl24e rps28e rps28e rpl7ae rpl7ae gltX gltX rps2P rps2P rpoK rpoK rpoN rpoN rps9p rps9p rpl13p rpl13p rpl18e rpl18e rpoD rpoD rps11p rps11p rps4p rps4p rps13p rps13p priS priS tfb-4 tfb-4 glmS-2 glmS-2 APW98194.1 APW98194.1 ef1B ef1B APW98130.1 APW98130.1 nusG nusG APW98111.1 APW98111.1 APW98108.1 APW98108.1 rpl21e rpl21e APW98097.1 APW98097.1 tyrS tyrS aspC aspC rpl37e rpl37e APW98011.1 APW98011.1 APW97993.1 APW97993.1 APW97971.1 APW97971.1 rpl15e rpl15e thrS thrS APW97918.1 APW97918.1 APX00045.1 APX00045.1 APW97910.1 APW97910.1 eif2b eif2b eif1a-2 eif1a-2 eif5a eif5a dnaG dnaG valS valS rps24e rps24e rps27ae rps27ae APW97668.1 APW97668.1 APW97664.1 APW97664.1 APW97661.1 APW97661.1 APW97657.1 APW97657.1 APW97638.1 APW97638.1 APW97601.1 APW97601.1 hisS hisS rps19e rps19e lysK-2 lysK-2 spt4 spt4 APW97552.1 APW97552.1 eif2g eif2g APW97540.1 APW97540.1 APW97527.1 APW97527.1 rpl40e rpl40e tfx tfx APW97481.1 APW97481.1 prf1 prf1 rps6e rps6e trpS trpS pheS pheS pheT pheT leuS leuS ileS ileS eif1a eif1a tbp tbp rpl39e rpl39e rpl31e rpl31e eif6 eif6 rplX rplX APW97147.1 APW97147.1 APW97146.1 APW97146.1 APW97138.1 APW97138.1 APW97136.1 APW97136.1 glmS glmS tfb-3 tfb-3 polB polB tuf tuf alaS alaS APW97001.1 APW97001.1 polC polC priL priL rrmJ rrmJ APW96925.1 APW96925.1 APW96891.1 APW96891.1 APW96871.1 APW96871.1 tfb-2 tfb-2 rpl10e rpl10e APW96834.1 APW96834.1 APW96771.1 APW96771.1 APW96770.1 APW96770.1 APW96767.1 APW96767.1 APW96751.1 APW96751.1 APW96748.1 APW96748.1 APW96732.1 APW96732.1 APW96715.1 APW96715.1 serS serS fusA fusA rps7 rps7 rps12P rps12P nusA nusA rpoA2 rpoA2 APW96675.1 APW96675.1 APW96674.1 APW96674.1 APW96673.1 APW96673.1 rpoH rpoH APW96666.1 APW96666.1 gatD gatD APW96614.1 APW96614.1 tfb tfb rps10 rps10 APW96469.1 APW96469.1 APW96467.1 APW96467.1 APW96464.1 APW96464.1 infB infB gatB gatB metG metG APW96308.1 APW96308.1 APW96302.1 APW96302.1 APW96301.1 APW96301.1 APW96273.1 APW96273.1 proS proS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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rps10p30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
tuf-2Translation elongation factor EF-1 subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (420 aa)
rpoPDNA-directed RNA polymerase subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. (44 aa)
rpl37ae50S ribosomal protein L37; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family. (87 aa)
APW99842.1Polysaccharide synthesis protein GtrA; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
APW99841.1dolichol-P-glucose transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
rpl44e50S ribosomal protein L44e; Binds to the 23S rRNA. (93 aa)
rps27e30S ribosomal protein S27e; Derived by automated computational analysis using gene prediction method: Protein Homology. (57 aa)
eif2aTranslation initiation factor IF-2 subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family. (266 aa)
leuS-2leucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (924 aa)
APW99713.1ATP-dependent carboxylate-amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
tfeTranscription factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems [...] (177 aa)
rps15pExonuclease; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
rps3ae30S ribosomal protein S3ae; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS1 family. (213 aa)
pthaminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. (112 aa)
APW99344.1DNA polymerase elongation subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (906 aa)
APW99330.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
APW99285.1Aminotransferase DegT; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DegT/DnrJ/EryC1 family. (413 aa)
APW99283.1Nucleotide sugar dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (500 aa)
APX00121.1Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
tfb-6Transcription initiation factor IIB 3; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (321 aa)
APW99267.1Aminotransferase DegT; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DegT/DnrJ/EryC1 family. (376 aa)
glmS-5Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (604 aa)
APW99185.1Initiation factor 2B; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eIF-2B alpha/beta/delta subunits family. (283 aa)
APW99173.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (508 aa)
APW99166.1Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa)
APW99055.1Transcription initiation factor IIB 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
gatCasparaginyl/glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (92 aa)
gatAaspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (423 aa)
APX00108.1MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (116 aa)
rpoLDNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (94 aa)
cysScysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
gatEglutamyl-tRNA(Gln) amidotransferase subunit E; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (624 aa)
rps17E30S ribosomal protein S17e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS17 family. (63 aa)
APW98903.1Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)
APW98901.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (824 aa)
C445_21026Hypothetical protein; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa)
APW98887.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (420 aa)
APW98882.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
tfb-5Transcription initiation factor IIB 2; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (327 aa)
glmS-3Nucleotidyl transferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (604 aa)
APW98822.1GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (533 aa)
rpl3p50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (339 aa)
rpl4lp50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (250 aa)
rpl2350S ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (84 aa)
rpl2p50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (240 aa)
rps19p30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (140 aa)
rpl22p50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (164 aa)
rps3p30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (318 aa)
rpl2950S ribosomal protein L29; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL29 family. (75 aa)
rps17p30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (144 aa)
rpl14p50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa)
rpl24p50S ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit. (122 aa)
rps4e30S ribosomal protein S4e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS4 family. (250 aa)
rpl5p50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (178 aa)
rps14P30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles. (71 aa)
rps8p30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rpl6p50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa)
rpl32e50S ribosomal protein L32e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL32 family. (250 aa)
rpl19e50S ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (149 aa)
rpl18p50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (182 aa)
rps5p30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy. (226 aa)
rpl30p50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
rpl15p50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (169 aa)
rpl11p50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (162 aa)
rpl1P50S ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (210 aa)
rplP050S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (346 aa)
rpl12p50S ribosomal protein P1; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (113 aa)
APW98622.1alanyl-tRNA editing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
ligDNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (585 aa)
APW98588.1Transcription factor S; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (109 aa)
dbhDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. (456 aa)
APW98574.1Transcription initiation factor IIB 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
APW98544.1Cyclin; Derived by automated computational analysis using gene prediction method: Protein Homology. (102 aa)
rps8e30S ribosomal protein S8e; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)
argSarginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (631 aa)
APW98450.1L-asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
APW98424.1DNA polymerase I; Derived by automated computational analysis using gene prediction method: Protein Homology. (725 aa)
rpl24e50S ribosomal protein L24e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL24 family. (116 aa)
rps28e30S ribosomal protein S28e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS28 family. (74 aa)
rpl7aeHypothetical protein; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (120 aa)
gltXglutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (587 aa)
rps2P30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family. (266 aa)
rpoKDNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (61 aa)
rpoNDNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (64 aa)
rps9p30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family. (132 aa)
rpl13p50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (151 aa)
rpl18e50S ribosomal protein L18e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL18 family. (117 aa)
rpoDDNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. (249 aa)
rps11p30S ribosomal protein S11; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (129 aa)
rps4p30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (173 aa)
rps13p30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (171 aa)
priSDNA primase; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play [...] (391 aa)
tfb-4Transcription initiation factor IIB 3; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (320 aa)
glmS-2Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (600 aa)
APW98194.1GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
ef1BElongation factor 1-beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (88 aa)
APW98130.1DNA polymerase/3'-5' exonuclease PolX; Derived by automated computational analysis using gene prediction method: Protein Homology. (583 aa)
nusGTranscription elongation factor Spt5; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (145 aa)
APW98111.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
APW98108.1DNA-directed RNA polymerase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
rpl21e50S ribosomal protein L21e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL21 family. (102 aa)
APW98097.1DNA-directed RNA polymerase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
tyrStyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (326 aa)
aspCaspartate--tRNA(Asn) ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (434 aa)
rpl37e50S ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (58 aa)
APW98011.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (718 aa)
APW97993.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (741 aa)
APW97971.1DUF4442 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
rpl15e50S ribosomal protein L15e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL15 family. (196 aa)
thrSthreonine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (660 aa)
APW97918.1Oligosaccharyl transferase, archaeosortase A system-associated; Derived by automated computational analysis using gene prediction method: Protein Homology. (964 aa)
APX00045.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
APW97910.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
eif2bTranslation initiation factor IF-2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (203 aa)
eif1a-2Translation initiation factor 1A 2; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (94 aa)
eif5aTranslation initiation factor IF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (124 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (494 aa)
valSvaline--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (893 aa)
rps24e30S ribosomal protein S24e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS24 family. (106 aa)
rps27ae30S ribosomal protein S27ae; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS31 family. (44 aa)
APW97668.1Nitrous oxide reductase accessory protein NosL/NosD; Derived by automated computational analysis using gene prediction method: Protein Homology. (656 aa)
APW97664.1Nitrous oxide reductase accessory protein NosL; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
APW97661.1Nitrous oxide reductase accessory protein NosL/NosD; Derived by automated computational analysis using gene prediction method: Protein Homology. (658 aa)
APW97657.1tRNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa)
APW97638.1RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
APW97601.1Ribosome biogenesis/translation initiation ATPase RLI; Derived by automated computational analysis using gene prediction method: Protein Homology. (604 aa)
hisShistidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (432 aa)
rps19e30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (151 aa)
lysK-2lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (566 aa)
spt4DNA-directed RNA polymerase subunit E'; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. (65 aa)
APW97552.1DNA-directed RNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
eif2gTranslation initiation factor IF-2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (410 aa)
APW97540.1Translation initiation factor; In yeast this protein is involved in start site selection during the initiation of translation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SUI1 family. (97 aa)
APW97527.1Initiation factor 2B; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eIF-2B alpha/beta/delta subunits family. (480 aa)
rpl40e50S ribosomal protein L40e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family. (49 aa)
tfxRNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
APW97481.1DNA mismatch repair protein MutT; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
prf1Peptide chain release factor 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (419 aa)
rps6e30S ribosomal protein S6e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS6 family. (131 aa)
trpStryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). (535 aa)
pheSphenylalanyl--tRNA ligase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (504 aa)
pheTphenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (587 aa)
leuSleucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (915 aa)
ileSisoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1070 aa)
eif1aTranslation initiation factor eIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (96 aa)
tbpTATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (186 aa)
rpl39e50S ribosomal protein L39e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL39 family. (50 aa)
rpl31e50S ribosomal protein L31e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribosomal protein L31e family. (92 aa)
eif6Translation initiation factor IF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (221 aa)
rplX50S ribosomal protein L18a; Derived by automated computational analysis using gene prediction method: Protein Homology. (58 aa)
APW97147.1Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
APW97146.1Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
APW97138.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
APW97136.1Nucleotide sugar dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (477 aa)
glmSGlutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (602 aa)
tfb-3Transcription initiation factor IIB 3; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (321 aa)
polBDNA polymerase II; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (519 aa)
tufTranslation elongation factor EF-1 subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (422 aa)
alaSalanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (928 aa)
APW97001.1glycine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (590 aa)
polCDNA polymerase II large subunit, intein-containing; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1709 aa)
priLDNA primase; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (370 aa)
rrmJ23S rRNA (uridine(2552)-2'-O)-methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (258 aa)
APW96925.1Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
APW96891.1Translation initiation factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SUI1 family. (99 aa)
APW96871.1tryptophan--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (415 aa)
tfb-2Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (307 aa)
rpl10e50S ribosomal protein L16; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL16 family. (176 aa)
APW96834.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
APW96771.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
APW96770.1Capsule biosynthesis protein CapD; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
APW96767.1Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
APW96751.1Copper-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
APW96748.1Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
APW96732.1Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
APW96715.1Phenylacetic acid degradation protein PaaD; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
serSserine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (459 aa)
fusAElongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (728 aa)
rps730S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (202 aa)
rps12P30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (142 aa)
nusATranscription elongation factor NusA; Participates in transcription termination. Belongs to the NusA family. (168 aa)
rpoA2DNA-directed RNA polymerase subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (404 aa)
APW96675.1DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (974 aa)
APW96674.1DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (609 aa)
APW96673.1DNA-directed RNA polymerase subunit B'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (525 aa)
rpoHDNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (75 aa)
APW96666.1DNA-directed RNA polymerase subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
gatDglutamyl-tRNA(Gln) amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (414 aa)
APW96614.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
tfbTranscription initiation factor IIB 2; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (328 aa)
rps1030S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (111 aa)
APW96469.1proline--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
APW96467.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa)
APW96464.1Transcription factor S; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (102 aa)
infBTranslation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (611 aa)
gatBaspartyl/glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (497 aa)
metGmethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (707 aa)
APW96308.1Deoxyribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa)
APW96302.1Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
APW96301.1DUF368 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
APW96273.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
proSproline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (493 aa)
Your Current Organism:
Halobiforma lacisalsi
NCBI taxonomy Id: 358396
Other names: H. lacisalsi AJ5, Halobiforma lacisalsi AJ5, Halobiforma lacisalsi str. AJ5, Halobiforma lacisalsi strain AJ5
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