STRINGSTRING
pyrG pyrG carA carA tmk tmk APW96634.1 APW96634.1 APW96651.1 APW96651.1 APW96899.1 APW96899.1 upp upp APW97424.1 APW97424.1 pyrH pyrH pyrE pyrE APW98106.1 APW98106.1 APW98248.1 APW98248.1 ndk ndk pyrI pyrI pyrB pyrB APW98548.1 APW98548.1 APW98550.1 APW98550.1 pyrF pyrF APW98931.1 APW98931.1 cmk cmk APW99299.1 APW99299.1 dcd dcd surE surE udk udk carB carB APW99743.1 APW99743.1 surE-2 surE-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (563 aa)
carACarbamoyl-phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (358 aa)
tmkdTMP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
APW96634.1Uridine phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
APW96651.1Bifunctional metallophosphatase/5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (670 aa)
APW96899.1Dihydroorotase; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (225 aa)
APW97424.1Deoxyuridine 5'-triphosphate nucleotidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (248 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (178 aa)
APW98106.1Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
APW98248.1Orotate phosphoribosyltransferase-like protein; Purine/pyrimidine phosphoribosyltransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (154 aa)
pyrIAspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (156 aa)
pyrBAspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
APW98548.1Uridine phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
APW98550.1Cytidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily. (265 aa)
APW98931.1Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1044 aa)
cmkCytidylate kinase; Catalyzes the formation of (d)CDP from ATP and (d)CMP; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
APW99299.1Dihydroorotate dehydrogenase (quinone); Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
dcdDeoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (198 aa)
surE5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (275 aa)
udkUridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
carBCarbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1057 aa)
APW99743.1Zn-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
surE-25'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (327 aa)
Your Current Organism:
Halobiforma lacisalsi
NCBI taxonomy Id: 358396
Other names: H. lacisalsi AJ5, Halobiforma lacisalsi AJ5, Halobiforma lacisalsi str. AJ5, Halobiforma lacisalsi strain AJ5
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.