31 items (Halobiforma lacisalsi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APW96372.1	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (672 aa)
	APW96726.1	Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
	APW96729.1	3-ketoacyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
	APW96913.1	acetyl-CoA acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
	APW97047.1	D-arabinose dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
	APW97342.1	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa)
	APW97647.1	acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (658 aa)
	APW97723.1	Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
	APW97787.1	methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (566 aa)
	APW98067.1	3-ketoacyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
	sucC	succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (383 aa)
	sucD	succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
	APW98701.1	methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
	APW98704.1	methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (561 aa)
	APW98782.1	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (698 aa)
	mgsA	Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (122 aa)
	APW98852.1	AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (545 aa)
	APW99176.1	acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (559 aa)
	APW99211.1	3-ketoacyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
	APW99230.1	Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)
	APW99300.1	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
	APW99583.1	2-ketoglutarate ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
	APW99584.1	2-ketoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (634 aa)
	APW99669.1	acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (662 aa)
	APW99671.1	Acetyl-coenzyme A synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (658 aa)
	APW99815.1	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa)
	APW99816.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (119 aa)
	rrf	5S ribosomal RNA; Derived by automated computational analysis using gene prediction method: cmsearch. (612 aa)
	APW99860.1	3-ketoacyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
	APW99864.1	methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
	APW99941.1	CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (897 aa)

Your Current Organism:

Halobiforma lacisalsi

NCBI taxonomy Id: 358396
Other names: H. lacisalsi AJ5, Halobiforma lacisalsi AJ5, Halobiforma lacisalsi str. AJ5, Halobiforma lacisalsi strain AJ5

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APW96372.1	APW96729.1	CHINAEXTREME_00710	CHINAEXTREME_02585	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-ketoacyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.789
APW96372.1	APW96913.1	CHINAEXTREME_00710	CHINAEXTREME_03625	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.789
APW96372.1	APW97647.1	CHINAEXTREME_00710	CHINAEXTREME_07620	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.678
APW96372.1	APW98067.1	CHINAEXTREME_00710	CHINAEXTREME_09840	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-ketoacyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.789
APW96372.1	APW98782.1	CHINAEXTREME_00710	CHINAEXTREME_13750	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.929
APW96372.1	APW98852.1	CHINAEXTREME_00710	CHINAEXTREME_14135	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.716
APW96372.1	APW99176.1	CHINAEXTREME_00710	CHINAEXTREME_15980	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.707
APW96372.1	APW99211.1	CHINAEXTREME_00710	CHINAEXTREME_16165	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-ketoacyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.789
APW96372.1	APW99300.1	CHINAEXTREME_00710	CHINAEXTREME_16650	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.789
APW96372.1	APW99583.1	CHINAEXTREME_00710	CHINAEXTREME_18210	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-ketoglutarate ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.916
APW96372.1	APW99584.1	CHINAEXTREME_00710	CHINAEXTREME_18215	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-ketoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.919
APW96372.1	APW99669.1	CHINAEXTREME_00710	CHINAEXTREME_18670	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.680
APW96372.1	APW99671.1	CHINAEXTREME_00710	CHINAEXTREME_18680	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetyl-coenzyme A synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.680
APW96372.1	APW99815.1	CHINAEXTREME_00710	CHINAEXTREME_19460	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.925
APW96372.1	APW99816.1	CHINAEXTREME_00710	CHINAEXTREME_19465	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
APW96372.1	APW99860.1	CHINAEXTREME_00710	CHINAEXTREME_19715	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-ketoacyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.789
APW96372.1	APW99941.1	CHINAEXTREME_00710	CHINAEXTREME_20165	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	CoA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.929
APW96372.1	rrf	CHINAEXTREME_00710	CHINAEXTREME_19510	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	5S ribosomal RNA; Derived by automated computational analysis using gene prediction method: cmsearch.	0.927
APW96372.1	sucC	CHINAEXTREME_00710	CHINAEXTREME_10645	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.852
APW96372.1	sucD	CHINAEXTREME_00710	CHINAEXTREME_10650	acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.841