STRINGSTRING
B4167_0191 B4167_0191 gcvH gcvH AcnA AcnA GlnA GlnA B4167_0499 B4167_0499 B4167_0706 B4167_0706 mce mce B4167_0759 B4167_0759 mdh mdh gcvT gcvT gcvPA gcvPA gcvPB gcvPB B4167_1146 B4167_1146 B4167_1163 B4167_1163 ycsA ycsA thlA thlA B4167_1289 B4167_1289 glyA glyA B4167_1847 B4167_1847 katA katA LpdA LpdA LpdA-2 LpdA-2 B4167_2824 B4167_2824 B4167_2988 B4167_2988 B4167_3481 B4167_3481 aceA aceA B4167_3644 B4167_3644 B4167_3766 B4167_3766 B4167_3767 B4167_3767 bfmBC bfmBC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
B4167_0191Glyoxylate reductase / Glyoxylate reductase / Hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
gcvHHypothetical protein; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family. (128 aa)
AcnAAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (909 aa)
GlnAGlutamine synthetase type I. (445 aa)
B4167_0499Hypothetical protein; Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases, YtcI -like protein. (527 aa)
B4167_0706Acetyl-coenzyme A carboxyl transferase alpha chain. (517 aa)
mceMethylmalonyl-CoA epimerase. (133 aa)
B4167_0759Citrate synthase (si); Belongs to the citrate synthase family. (371 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (310 aa)
gcvTAminomethyltransferase (glycine cleavage system T protein); The glycine cleavage system catalyzes the degradation of glycine. (370 aa)
gcvPAGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (449 aa)
gcvPBGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (486 aa)
B4167_1146Acetyl-coenzyme A synthetase. (571 aa)
B4167_11633-ketoacyl-CoA thiolase / Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
ycsATartrate dehydrogenase / Tartrate decarboxylase / D-malic enzyme. (362 aa)
thlA3-ketoacyl-CoA thiolase / Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
B4167_12893-ketoacyl-CoA thiolase [isoleucine degradation]; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (419 aa)
B4167_1847Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (685 aa)
katACatalase; Belongs to the catalase family. (494 aa)
LpdADihydrolipoamide dehydrogenase of acetoin dehydrogenase. (450 aa)
LpdA-2Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex. (470 aa)
B4167_2824Hypothetical protein; Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases, YtcI -like protein. (524 aa)
B4167_2988Glycerate kinase; Belongs to the glycerate kinase type-1 family. (378 aa)
B4167_3481Malate synthase; Belongs to the malate synthase family. (525 aa)
aceAIsocitrate lyase. (425 aa)
B4167_3644FIG00673147: hypothetical protein. (430 aa)
B4167_3766Methylmalonyl-CoA mutase. (731 aa)
B4167_3767Methylmalonyl-CoA mutase. (645 aa)
bfmBCDihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase. (472 aa)
Your Current Organism:
Bacillus thermoamylovorans
NCBI taxonomy Id: 35841
Other names: B. thermoamylovorans, Bacillus sp. LMG 18084, Bacillus sp. R-6546, Bacillus sp. R-7440, Bacillus sp. R-7764, LMG 18084, LMG:18084, Lactobacter thermoamylovorans, strain DKP
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