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B4167_0499 B4167_0499 mgsA mgsA B4167_0706 B4167_0706 mce mce accD accD accA accA B4167_0889 B4167_0889 B4167_1146 B4167_1146 B4167_1163 B4167_1163 thlA thlA lpsJ lpsJ Pta Pta B4167_1289 B4167_1289 B4167_1292 B4167_1292 B4167_1798 B4167_1798 B4167_1901 B4167_1901 B4167_1932 B4167_1932 B4167_1933 B4167_1933 LpdA LpdA ldh ldh LpdA-2 LpdA-2 B4167_2656 B4167_2656 B4167_2824 B4167_2824 sucC sucC sucD sucD B4167_3766 B4167_3766 B4167_3767 B4167_3767 B4167_3768 B4167_3768 bfmBAB bfmBAB bfmBAA bfmBAA bfmBC bfmBC accC1 accC1 AccB AccB B4167_3802 B4167_3802
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
B4167_0499Hypothetical protein; Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases, YtcI -like protein. (527 aa)
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (135 aa)
B4167_0706Acetyl-coenzyme A carboxyl transferase alpha chain. (517 aa)
mceMethylmalonyl-CoA epimerase. (133 aa)
accDAcetyl-coenzyme A carboxyl transferase beta chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (287 aa)
accAAcetyl-coenzyme A carboxyl transferase alpha chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)
B4167_0889Hypothetical protein; Threonine dehydrogenase and related Zn-dependent dehydrogenases. (106 aa)
B4167_1146Acetyl-coenzyme A synthetase. (571 aa)
B4167_11633-ketoacyl-CoA thiolase / Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
thlA3-ketoacyl-CoA thiolase / Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
lpsJ3-oxoadipate CoA-transferase subunit B. (216 aa)
PtaPhosphate acetyltransferase. (323 aa)
B4167_12893-ketoacyl-CoA thiolase [isoleucine degradation]; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
B4167_1292Butyryl-CoA dehydrogenase. (377 aa)
B4167_1798Hypothetical protein; Oxidoreductase of aldo/keto reductase family, subgroup 1. (276 aa)
B4167_1901Glycerol dehydrogenase. (373 aa)
B4167_1932Biotin carboxyl carrier protein of methylcrotonyl-CoA carboxylase. (70 aa)
B4167_1933Biotin carboxylase of methylcrotonyl-CoA carboxylase. (454 aa)
LpdADihydrolipoamide dehydrogenase of acetoin dehydrogenase. (450 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (316 aa)
LpdA-2Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex. (470 aa)
B4167_2656Alcohol dehydrogenase. (330 aa)
B4167_2824Hypothetical protein; Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases, YtcI -like protein. (524 aa)
sucCSuccinyl-CoA ligase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (387 aa)
sucDSuccinyl-CoA ligase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa)
B4167_3766Methylmalonyl-CoA mutase. (731 aa)
B4167_3767Methylmalonyl-CoA mutase. (645 aa)
B4167_3768Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. (417 aa)
bfmBABBranched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit. (327 aa)
bfmBAABranched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit. (330 aa)
bfmBCDihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase. (472 aa)
accC1Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (452 aa)
AccBHypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (172 aa)
B4167_3802Pyruvate formate-lyase. (743 aa)
Your Current Organism:
Bacillus thermoamylovorans
NCBI taxonomy Id: 35841
Other names: B. thermoamylovorans, Bacillus sp. LMG 18084, Bacillus sp. R-6546, Bacillus sp. R-7440, Bacillus sp. R-7764, LMG 18084, LMG:18084, Lactobacter thermoamylovorans, strain DKP
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