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tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (213 aa) | ||||
BAH41348.1 | Conserved hypothetical protein; Belongs to the carbohydrate kinase PfkB family. (362 aa) | ||||
psuG | Conserved hypothetical protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (308 aa) | ||||
BAH41634.1 | Hypothetical protein. (191 aa) | ||||
BAH41914.1 | Conserved hypothetical protein. (234 aa) | ||||
BAH42362.1 | Conserved hypothetical protein. (753 aa) | ||||
BAH42589.1 | Conserved hypothetical protein. (297 aa) | ||||
ushA | Probable 5'-nucleotidase precursor; Belongs to the 5'-nucleotidase family. (625 aa) | ||||
BAH42837.1 | Probable 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Belongs to the 5'-nucleotidase family. (662 aa) | ||||
udk | Uridine kinase. (214 aa) | ||||
cdd | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (132 aa) | ||||
dck | Deoxyadenosine/deoxycytidine kinase. (230 aa) | ||||
punA | Purine nucleoside phosphorylase I; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (269 aa) | ||||
pdp | Probable pyrimidine-nucleoside phosphorylase. (435 aa) | ||||
cmk | Cytidylate kinase. (223 aa) | ||||
ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (147 aa) | ||||
dut | Putative deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (176 aa) | ||||
deoD | Purine nucleoside phosphorylase II. (235 aa) | ||||
nrdF | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (316 aa) | ||||
nrdE | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (694 aa) | ||||
BAH44147.1 | Conserved hypothetical protein. (381 aa) | ||||
pydC | Beta-alanine synthase. (296 aa) | ||||
pydB | Dihydropyrimidinase. (461 aa) | ||||
BAH44214.1 | Conserved hypothetical protein. (425 aa) | ||||
gltB | Probable glutamate synthase small chain. (448 aa) | ||||
pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa) | ||||
pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (209 aa) | ||||
pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (245 aa) | ||||
pyrAB | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1070 aa) | ||||
pyrAA | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (365 aa) | ||||
pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (426 aa) | ||||
pyrB | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (313 aa) | ||||
pyrR | Pyrimidine operon regulatory protein/uracil phosphoribosyltransferase; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (179 aa) | ||||
surE | Putative nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (265 aa) | ||||
BAH45043.1 | Conserved hypothetical protein. (317 aa) | ||||
BAH45221.1 | Conserved hypothetical protein. (319 aa) | ||||
tysY | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa) | ||||
yunD | Putative nucleotidase; Belongs to the 5'-nucleotidase family. (484 aa) | ||||
pyrD | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (363 aa) | ||||
carB | Arginine-specific carbamoyl-phosphate synthase large chain. (1080 aa) | ||||
carA | Arginine-specific carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (368 aa) | ||||
upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa) | ||||
tdk | Thymidine kinase. (191 aa) | ||||
pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (531 aa) | ||||
BAH46543.1 | Putative purine nucleoside phosphorylase. (240 aa) | ||||
BAH46650.1 | Putative 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor; Belongs to the 5'-nucleotidase family. (662 aa) |