(74 nodes) Peptidyl-histidine phosphorylation network (Clostridium citroniae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SFS05410.1	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (585 aa)
	SFS10343.1	Diguanylate cyclase (GGDEF) domain-containing protein. (636 aa)
	SFS11241.1	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (608 aa)
	SFS11794.1	GHKL domain-containing protein. (61 aa)
	SFS11868.1	His Kinase A (phospho-acceptor) domain-containing protein. (852 aa)
	SFS11928.1	Two-component system, sensor histidine kinase YesM. (597 aa)
	SFS12113.1	GHKL domain-containing protein. (435 aa)
	SFS12193.1	PAS domain-containing protein. (560 aa)
	SFS12255.1	Signal transduction histidine kinase. (512 aa)
	SFS09781.1	Two-component system, sensor histidine kinase YesM. (575 aa)
	SFS09845.1	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (564 aa)
	SFS09995.1	Two-component system, sensor histidine kinase YesM. (585 aa)
	hprK	Hpr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] (310 aa)
	SFS16080.1	Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR. (466 aa)
	SFS16275.1	Two-component system, sensor histidine kinase YesM. (602 aa)
	SFS17129.1	Signal transduction histidine kinase. (367 aa)
	SFS17277.1	Signal transduction histidine kinase. (492 aa)
	SFS14559.1	Two-component system, sensor histidine kinase YesM. (583 aa)
	SFS18726.1	HAMP domain-containing protein. (584 aa)
	SFS19212.1	Diguanylate cyclase (GGDEF) domain-containing protein. (331 aa)
	SFS20194.1	Two-component system, sensor histidine kinase YesM. (594 aa)
	SFS20005.1	Hypothetical protein. (345 aa)
	SFS20143.1	GHKL domain-containing protein. (445 aa)
	SFS21002.1	HAMP domain-containing protein. (507 aa)
	SFS21550.1	Signal transduction histidine kinase. (489 aa)
	SFS21719.1	Two-component system, sensor histidine kinase YesM. (628 aa)
	SFS21740.1	Signal transduction histidine kinase. (354 aa)
	SFS21744.1	Signal transduction histidine kinase. (447 aa)
	SFS21800.1	Two-component system, sensor histidine kinase YesM. (577 aa)
	SFS21837.1	Two-component system, sensor histidine kinase YesM. (513 aa)
	SFS21955.1	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (421 aa)
	SFS21211.1	Two-component system, sensor histidine kinase YesM. (601 aa)
	SFS22305.1	His Kinase A (phospho-acceptor) domain-containing protein. (440 aa)
	SFS22323.1	Two-component system, sensor histidine kinase YesM. (604 aa)
	SFS22330.1	Signal transduction histidine kinase. (462 aa)
	SFS22369.1	Serine/threonine protein kinase. (1199 aa)
	SFS22399.1	Signal transduction histidine kinase. (483 aa)
	SFS22464.1	Two-component system, OmpR family, sensor histidine kinase VanS. (382 aa)
	SFS22116.1	Two-component system, LytT family, sensor histidine kinase LytS. (567 aa)
	SFS22548.1	Ligand-binding sensor domain-containing protein. (443 aa)
	SFS22862.1	GHKL domain-containing protein. (627 aa)
	SFS22866.1	Signal transduction histidine kinase. (467 aa)
	SFS22947.1	Histidine kinase. (453 aa)
	SFS22793.1	Signal transduction histidine kinase. (348 aa)
	SFS22802.1	Two-component system, sensor histidine kinase YesM. (603 aa)
	SFS22822.1	Signal transduction histidine kinase. (839 aa)
	SFS23004.1	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (561 aa)
	SFS23026.1	Protein of unknown function. (520 aa)
	SFS23376.1	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (599 aa)
	SFS23579.1	Signal transduction histidine kinase. (912 aa)
	SFS23543.1	Two-component system, sensor histidine kinase YesM. (594 aa)
	SFS23563.1	Signal transduction histidine kinase. (471 aa)
	SFS23574.1	Two-component system, chemotaxis family, sensor kinase CheA. (720 aa)
	SFS23659.1	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (611 aa)
	SFR95277.1	His Kinase A (phospho-acceptor) domain-containing protein. (519 aa)
	SFR95927.1	HAMP domain-containing protein. (490 aa)
	SFR83290.1	Two-component system, OmpR family, sensor histidine kinase KdpD. (369 aa)
	SFR84530.1	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (504 aa)
	SFR84941.1	Two-component system, sensor histidine kinase YesM. (601 aa)
	SFR86982.1	Two-component system, sensor histidine kinase YesM. (595 aa)
	SFR87141.1	Signal transduction histidine kinase. (468 aa)
	SFR87617.1	Two-component system, OmpR family, sensor histidine kinase KdpD. (663 aa)
	SFR87672.1	Two-component system, OmpR family, sensor histidine kinase KdpD. (493 aa)
	SFR88067.1	Two-component system, sensor histidine kinase YesM. (600 aa)
	SFR83759.1	Signal transduction histidine kinase. (819 aa)
	SFR93387.1	Two-component system, sensor histidine kinase YesM. (611 aa)
	SFR93845.1	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (496 aa)
	SFR94077.1	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (497 aa)
	SFR94571.1	HAMP domain-containing protein. (579 aa)
	SFS01538.1	GHKL domain-containing protein. (230 aa)
	SFS03823.1	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (565 aa)
	SFS04128.1	HAMP domain-containing protein. (521 aa)
	SFS04521.1	Signal transduction histidine kinase. (378 aa)
	SFS04644.1	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (588 aa)

Your Current Organism:

Clostridium citroniae

NCBI taxonomy Id: 358743
Other names: CCUG 52203, Clostridium citroniae Warren et al. 2007, DSM 19261, [. citroniae, [Clostridium] citroniae, strain RMA 16102

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFR83290.1	SFR87141.1	SAMN05216568_10113	SAMN05216568_101332	Two-component system, OmpR family, sensor histidine kinase KdpD.	Signal transduction histidine kinase.	0.426
SFR83290.1	SFR87617.1	SAMN05216568_10113	SAMN05216568_101366	Two-component system, OmpR family, sensor histidine kinase KdpD.	Two-component system, OmpR family, sensor histidine kinase KdpD.	0.923
SFR83290.1	SFS04521.1	SAMN05216568_10113	SAMN05216568_102355	Two-component system, OmpR family, sensor histidine kinase KdpD.	Signal transduction histidine kinase.	0.441
SFR83290.1	SFS11868.1	SAMN05216568_10113	SAMN05216568_103313	Two-component system, OmpR family, sensor histidine kinase KdpD.	His Kinase A (phospho-acceptor) domain-containing protein.	0.799
SFR83290.1	SFS12255.1	SAMN05216568_10113	SAMN05216568_103357	Two-component system, OmpR family, sensor histidine kinase KdpD.	Signal transduction histidine kinase.	0.417
SFR83290.1	SFS16080.1	SAMN05216568_10113	SAMN05216568_104264	Two-component system, OmpR family, sensor histidine kinase KdpD.	Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR.	0.421
SFR83290.1	SFS17129.1	SAMN05216568_10113	SAMN05216568_104453	Two-component system, OmpR family, sensor histidine kinase KdpD.	Signal transduction histidine kinase.	0.438
SFR83290.1	SFS21002.1	SAMN05216568_10113	SAMN05216568_1071	Two-component system, OmpR family, sensor histidine kinase KdpD.	HAMP domain-containing protein.	0.411
SFR83290.1	SFS21550.1	SAMN05216568_10113	SAMN05216568_107170	Two-component system, OmpR family, sensor histidine kinase KdpD.	Signal transduction histidine kinase.	0.403
SFR83290.1	SFS21740.1	SAMN05216568_10113	SAMN05216568_107225	Two-component system, OmpR family, sensor histidine kinase KdpD.	Signal transduction histidine kinase.	0.416
SFR83290.1	SFS22305.1	SAMN05216568_10113	SAMN05216568_108138	Two-component system, OmpR family, sensor histidine kinase KdpD.	His Kinase A (phospho-acceptor) domain-containing protein.	0.417
SFR83290.1	SFS22330.1	SAMN05216568_10113	SAMN05216568_108149	Two-component system, OmpR family, sensor histidine kinase KdpD.	Signal transduction histidine kinase.	0.693
SFR83290.1	SFS22369.1	SAMN05216568_10113	SAMN05216568_108166	Two-component system, OmpR family, sensor histidine kinase KdpD.	Serine/threonine protein kinase.	0.575
SFR83290.1	SFS22399.1	SAMN05216568_10113	SAMN05216568_108180	Two-component system, OmpR family, sensor histidine kinase KdpD.	Signal transduction histidine kinase.	0.483
SFR83290.1	SFS22464.1	SAMN05216568_10113	SAMN05216568_108209	Two-component system, OmpR family, sensor histidine kinase KdpD.	Two-component system, OmpR family, sensor histidine kinase VanS.	0.466
SFR83290.1	SFS22793.1	SAMN05216568_10113	SAMN05216568_11032	Two-component system, OmpR family, sensor histidine kinase KdpD.	Signal transduction histidine kinase.	0.422
SFR83290.1	SFS22822.1	SAMN05216568_10113	SAMN05216568_11061	Two-component system, OmpR family, sensor histidine kinase KdpD.	Signal transduction histidine kinase.	0.802
SFR83290.1	SFS22866.1	SAMN05216568_10113	SAMN05216568_110106	Two-component system, OmpR family, sensor histidine kinase KdpD.	Signal transduction histidine kinase.	0.485
SFR83290.1	SFS23563.1	SAMN05216568_10113	SAMN05216568_11585	Two-component system, OmpR family, sensor histidine kinase KdpD.	Signal transduction histidine kinase.	0.571
SFR83290.1	SFS23574.1	SAMN05216568_10113	SAMN05216568_11596	Two-component system, OmpR family, sensor histidine kinase KdpD.	Two-component system, chemotaxis family, sensor kinase CheA.	0.422