STRINGSTRING
loaP loaP SFR95374.1 SFR95374.1 nusB nusB nadK nadK SFR96387.1 SFR96387.1 SFR96456.1 SFR96456.1 SFR84712.1 SFR84712.1 SFR84782.1 SFR84782.1 SFR84794.1 SFR84794.1 SFR85222.1 SFR85222.1 SFR85339.1 SFR85339.1 SFR83393.1 SFR83393.1 SFR83414.1 SFR83414.1 atpA atpA SFR86323.1 SFR86323.1 atpB atpB atpD atpD rpoN rpoN SFR86741.1 SFR86741.1 xpt xpt hpt hpt rho rho SFR88611.1 SFR88611.1 rfbD rfbD SFR89159.1 SFR89159.1 rfbC rfbC rpoB rpoB rpoC rpoC SFR83713.1 SFR83713.1 SFR90818.1 SFR90818.1 SFR92271.1 SFR92271.1 SFR92381.1 SFR92381.1 SFR92393.1 SFR92393.1 SFR92525.1 SFR92525.1 SFR92785.1 SFR92785.1 SFR83956.1 SFR83956.1 SFR93575.1 SFR93575.1 rfbD-2 rfbD-2 add add SFR94156.1 SFR94156.1 SFR94165.1 SFR94165.1 SFS02457.1 SFS02457.1 apt apt SFS02746.1 SFS02746.1 SFS03759.1 SFS03759.1 pyrC pyrC SFS04180.1 SFS04180.1 SFS04563.1 SFS04563.1 SFS04709.1 SFS04709.1 SFS04716.1 SFS04716.1 SFS04749.1 SFS04749.1 atpE atpE SFS06145.1 SFS06145.1 atpA-2 atpA-2 atpB-2 atpB-2 atpD-2 atpD-2 SFS06675.1 SFS06675.1 nusG nusG murA murA SFS10166.1 SFS10166.1 guaB guaB SFS10939.1 SFS10939.1 carB carB carA carA SFS11270.1 SFS11270.1 nrdG nrdG SFS11640.1 SFS11640.1 pyrG pyrG SFS12437.1 SFS12437.1 SFS09530.1 SFS09530.1 SFS12975.1 SFS12975.1 guaA guaA folD folD thyA thyA SFS09650.1 SFS09650.1 SFS14573.1 SFS14573.1 SFS15272.1 SFS15272.1 dnaG dnaG rpoD rpoD SFS15401.1 SFS15401.1 SFS15497.1 SFS15497.1 SFS15717.1 SFS15717.1 SFS15895.1 SFS15895.1 dacA dacA priA priA SFS16242.1 SFS16242.1 SFS16260.1 SFS16260.1 pyrB pyrB SFS16334.1 SFS16334.1 SFS16340.1 SFS16340.1 sigK sigK SFS16449.1 SFS16449.1 pyrH pyrH polC polC SFS16885.1 SFS16885.1 upp upp polA polA coaE coaE SFS17032.1 SFS17032.1 ackA ackA selA selA SFS14967.1 SFS14967.1 purD purD purN purN purM purM purE purE SFS18899.1 SFS18899.1 SFS19028.1 SFS19028.1 SFS19041.1 SFS19041.1 SFS19162.1 SFS19162.1 sigI sigI pyrE pyrE pyrD pyrD pyrK pyrK pyrF pyrF SFS18286.1 SFS18286.1 SFS20187.1 SFS20187.1 SFS20268.1 SFS20268.1 purC purC purF purF SFS20306.1 SFS20306.1 purA purA SFS20378.1 SFS20378.1 SFS20420.1 SFS20420.1 gmk gmk SFS20491.1 SFS20491.1 cinA cinA SFS20551.1 SFS20551.1 coaD coaD nadD nadD SFS20676.1 SFS20676.1 atpB-3 atpB-3 atpE-2 atpE-2 atpF atpF atpH atpH atpA-3 atpA-3 atpG atpG atpD-3 atpD-3 atpC atpC ackA-2 ackA-2 SFS20068.1 SFS20068.1 SFS20114.1 SFS20114.1 cmk cmk SFS21032.1 SFS21032.1 nadE nadE SFS21477.1 SFS21477.1 SFS21484.1 SFS21484.1 SFS21506.1 SFS21506.1 SFS21523.1 SFS21523.1 nusA nusA SFS21589.1 SFS21589.1 SFS21861.1 SFS21861.1 SFS21255.1 SFS21255.1 queH queH rpoD-2 rpoD-2 asrB asrB queA queA dinB dinB ackA-3 ackA-3 SFS22505.1 SFS22505.1 coaBC coaBC coaX coaX sigG sigG SFS22078.1 SFS22078.1 sigE sigE murA-2 murA-2 SFS22710.1 SFS22710.1 SFS22714.1 SFS22714.1 loaP-2 loaP-2 SFS22625.1 SFS22625.1 SFS22952.1 SFS22952.1 SFS22953.1 SFS22953.1 SFS22965.1 SFS22965.1 SFS23071.1 SFS23071.1 accD accD dnaX dnaX SFS22985.1 SFS22985.1 SFS23028.1 SFS23028.1 holB holB adk adk rpoA rpoA SFS23129.1 SFS23129.1 SFS23166.1 SFS23166.1 tgt tgt SFS23362.1 SFS23362.1 udp udp larB larB SFS23490.1 SFS23490.1 SFS23484.1 SFS23484.1 SFS23694.1 SFS23694.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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co-expression
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loaPTranscriptional antiterminator NusG. (170 aa)
SFR95374.1UDPglucose 6-dehydrogenase. (416 aa)
nusBNusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (144 aa)
nadKNAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (280 aa)
SFR96387.1RNA polymerase, sigma subunit, ECF family; Belongs to the sigma-70 factor family. ECF subfamily. (282 aa)
SFR96456.1Putative hydrolases of HD superfamily. (188 aa)
SFR84712.1Uridine phosphorylase. (254 aa)
SFR84782.1Uridine phosphorylase. (265 aa)
SFR84794.1Uridine phosphorylase. (252 aa)
SFR85222.1Flagellum-specific ATP synthase. (434 aa)
SFR85339.1RNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; Belongs to the sigma-70 factor family. (258 aa)
SFR83393.1V/A-type H+-transporting ATPase subunit K. (142 aa)
SFR83414.1H+-ATPase subunit E/Vma4. (193 aa)
atpAV/A-type H+-transporting ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (588 aa)
SFR86323.1RNA polymerase, sigma subunit, ECF family; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa)
atpBV/A-type H+-transporting ATPase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (463 aa)
atpDV/A-type H+-transporting ATPase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (205 aa)
rpoNRNA polymerase, sigma 54 subunit, RpoN/SigL. (461 aa)
SFR86741.1Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (347 aa)
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (194 aa)
hptHypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (175 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (590 aa)
SFR88611.1RNA polymerase sigma-70 factor, ECF subfamily. (159 aa)
rfbDdTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (286 aa)
SFR89159.1Carbamoyl-phosphate synthase large subunit. (337 aa)
rfbCdTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (184 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1292 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1233 aa)
SFR83713.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (452 aa)
SFR90818.1Acetyl-CoA carboxylase, carboxyltransferase component. (483 aa)
SFR92271.1Hypothetical protein. (470 aa)
SFR92381.1Biotin carboxylase. (399 aa)
SFR92393.1Biotin carboxylase. (435 aa)
SFR92525.1UDPglucose 6-dehydrogenase. (398 aa)
SFR92785.1Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (389 aa)
SFR83956.1RNA polymerase sigma-70 factor, ECF subfamily. (178 aa)
SFR93575.1Putative GTP pyrophosphokinase. (198 aa)
rfbD-2dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (297 aa)
addAdenosine deaminase. (331 aa)
SFR94156.1ppGpp synthetase catalytic domain-containing protein (RelA/SpoT-type nucleotidyltranferase). (275 aa)
SFR94165.1GrpB domain, predicted nucleotidyltransferase, UPF0157 family. (225 aa)
SFS02457.1Cytidylate kinase. (220 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (174 aa)
SFS02746.1GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (761 aa)
SFS03759.1Putative GTP pyrophosphokinase. (226 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (435 aa)
SFS04180.1HD domain-containing protein. (192 aa)
SFS04563.1Replication restart DNA helicase PriA. (357 aa)
SFS04709.1Cytidylate kinase. (201 aa)
SFS04716.1GMP synthase (glutamine-hydrolysing). (432 aa)
SFS04749.1RNA polymerase sigma factor, sigma-70 family. (140 aa)
atpEV/A-type H+-transporting ATPase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (197 aa)
SFS06145.1V/A-type H+-transporting ATPase subunit F. (106 aa)
atpA-2V/A-type H+-transporting ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (591 aa)
atpB-2V/A-type H+-transporting ATPase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (457 aa)
atpD-2V/A-type H+-transporting ATPase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (227 aa)
SFS06675.1DNA polymerase-3 subunit alpha. (240 aa)
nusGTranscription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. (172 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (430 aa)
SFS10166.1RNA polymerase sigma-70 factor, ECF subfamily. (221 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (484 aa)
SFS10939.1Uridine phosphorylase. (250 aa)
carBCarbamoyl-phosphate synthase large subunit. (1072 aa)
carACarbamoyl-phosphate synthase small subunit; Belongs to the CarA family. (368 aa)
SFS11270.1Cytidylate kinase. (211 aa)
nrdGAnaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (172 aa)
SFS11640.1Orotate phosphoribosyltransferase. (212 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (533 aa)
SFS12437.1Aspartate dehydrogenase. (261 aa)
SFS09530.1ferredoxin--NADP+ reductase. (296 aa)
SFS12975.1RNA polymerase, sigma subunit, ECF family; Belongs to the sigma-70 factor family. ECF subfamily. (265 aa)
guaAGMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. (513 aa)
folDMethylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (283 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (276 aa)
SFS09650.1Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (171 aa)
SFS14573.1Cytidylate kinase-like family protein. (194 aa)
SFS15272.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (290 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (629 aa)
rpoDRNA polymerase primary sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (374 aa)
SFS15401.1Uridine kinase. (550 aa)
SFS15497.1Cytidylate kinase-like family protein. (211 aa)
SFS15717.16-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase. (188 aa)
SFS15895.1DNA polymerase III catalytic subunit, DnaE type. (1161 aa)
dacADiadenylate cyclase; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (289 aa)
priAReplication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (752 aa)
SFS16242.1seryl-tRNA synthetase. (429 aa)
SFS16260.1Aspartate carbamoyltransferase regulatory subunit. (142 aa)
pyrBAspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (307 aa)
SFS16334.1IMP cyclohydrolase-like protein. (237 aa)
SFS16340.1Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. (392 aa)
sigKRNA polymerase, sigma 27/28 subunit, RpsK/SigK; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (210 aa)
SFS16449.1YARHG domain-containing protein. (505 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (233 aa)
polCDNA polymerase III catalytic subunit, PolC type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1539 aa)
SFS16885.1Transferase hexapeptide (six repeat-containing protein). (245 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (928 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (212 aa)
SFS17032.1ACT domain-containing protein; Belongs to the UPF0237 family. (90 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
selAL-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (467 aa)
SFS14967.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (485 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (424 aa)
purNFormyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (197 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase. (344 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (171 aa)
SFS18899.1Hypothetical protein. (140 aa)
SFS19028.1UDPglucose 6-dehydrogenase. (395 aa)
SFS19041.1RNA polymerase sigma factor, sigma-70 family. (147 aa)
SFS19162.1CHC2 zinc finger. (229 aa)
sigIRNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; Belongs to the sigma-70 factor family. SigI subfamily. (243 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (226 aa)
pyrDDihydroorotate dehydrogenase (NAD+) catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (300 aa)
pyrKDihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (271 aa)
pyrFOrotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (305 aa)
SFS18286.1Putative GTP pyrophosphokinase. (239 aa)
SFS20187.1Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (468 aa)
SFS20268.1RNA polymerase sporulation-specific sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (239 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (235 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (482 aa)
SFS20306.1Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (478 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (425 aa)
SFS20378.1DNA polymerase-4; Belongs to the DNA polymerase type-Y family. (427 aa)
SFS20420.1Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (402 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (209 aa)
SFS20491.1DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (91 aa)
cinANicotinamide-nucleotide amidase; Belongs to the CinA family. (417 aa)
SFS20551.1Reverse transcriptase (RNA-dependent DNA polymerase). (331 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (163 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (215 aa)
SFS20676.1Putative HD superfamily hydrolase of NAD metabolism. (203 aa)
atpB-3ATP synthase F0 subcomplex A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (229 aa)
atpE-2ATP synthase F0 subcomplex C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (74 aa)
atpFATP synthase F0 subcomplex B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (163 aa)
atpHF-type H+-transporting ATPase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (171 aa)
atpA-3F-type H+-transporting ATPase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (502 aa)
atpGF-type H+-transporting ATPase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (298 aa)
atpD-3ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (466 aa)
atpCATP synthase F1 subcomplex epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (137 aa)
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
SFS20068.1RNA polymerase primary sigma factor. (199 aa)
SFS20114.1Phosphoribosylformylglycinamidine synthase. (1258 aa)
cmkCytidylate kinase. (225 aa)
SFS21032.1Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. (316 aa)
nadENAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (659 aa)
SFS21477.1Cytidylate kinase. (194 aa)
SFS21484.1DNA polymerase III, delta subunit. (325 aa)
SFS21506.1Chloramphenicol phosphotransferase-like protein. (152 aa)
SFS21523.1CHC2 zinc finger. (214 aa)
nusANusA antitermination factor; Participates in both transcription termination and antitermination. (390 aa)
SFS21589.1RNA polymerase, sigma subunit, SigV; Belongs to the sigma-70 factor family. ECF subfamily. (167 aa)
SFS21861.1Uridine phosphorylase. (280 aa)
SFS21255.1RNA polymerase primary sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (408 aa)
queHHypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (256 aa)
rpoD-2RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (381 aa)
asrBAnaerobic sulfite reductase subunit B. (263 aa)
queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (349 aa)
dinBDNA polymerase-4; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (421 aa)
ackA-3Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (410 aa)
SFS22505.1RNA polymerase sigma-70 factor, ECF subfamily. (176 aa)
coaBCPhosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (394 aa)
coaXType III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (258 aa)
sigGRNA polymerase, sigma subunit, RpsG/SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (258 aa)
SFS22078.1ppGpp synthetase catalytic domain-containing protein (RelA/SpoT-type nucleotidyltranferase). (430 aa)
sigERNA polymerase, sigma 29 subunit, SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (246 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (421 aa)
SFS22710.1Thymidylate kinase. (211 aa)
SFS22714.1Carbamoyl-phosphate synthase large subunit. (332 aa)
loaP-2Transcriptional antiterminator NusG. (170 aa)
SFS22625.1Cytidylate kinase. (212 aa)
SFS22952.1RNA polymerase, sigma subunit, SigV; Belongs to the sigma-70 factor family. ECF subfamily. (163 aa)
SFS22953.1Cytidylate kinase. (200 aa)
SFS22965.1DNA polymerase V. (508 aa)
SFS23071.1acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
accDacetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (572 aa)
dnaXDNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (539 aa)
SFS22985.1Glycosyl transferase family 2. (696 aa)
SFS23028.1Adenylate kinase. (180 aa)
holBDNA polymerase-3 subunit delta'. (329 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (320 aa)
SFS23129.1WbqC-like protein family protein. (239 aa)
SFS23166.1Cytidylate kinase. (201 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (381 aa)
SFS23362.1AAA domain-containing protein, putative AbiEii toxin, Type IV TA system. (487 aa)
udpUridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. (258 aa)
larBHypothetical protein. (247 aa)
SFS23490.1PucR C-terminal helix-turn-helix domain-containing protein. (516 aa)
SFS23484.1PucR C-terminal helix-turn-helix domain-containing protein. (524 aa)
SFS23694.1DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] (372 aa)
Your Current Organism:
Clostridium citroniae
NCBI taxonomy Id: 358743
Other names: CCUG 52203, Clostridium citroniae Warren et al. 2007, DSM 19261, [. citroniae, [Clostridium] citroniae, strain RMA 16102
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