STRINGSTRING
SFR96468.1 SFR96468.1 glgC glgC glgD glgD SFR85063.1 SFR85063.1 SFR87055.1 SFR87055.1 mutS2 mutS2 gyrB gyrB SFR87936.1 SFR87936.1 SFR88350.1 SFR88350.1 SFR92768.1 SFR92768.1 SFR92776.1 SFR92776.1 SFR93219.1 SFR93219.1 murQ murQ SFR94227.1 SFR94227.1 SFR94327.1 SFR94327.1 topB topB SFS01647.1 SFS01647.1 SFS02071.1 SFS02071.1 SFS03746.1 SFS03746.1 rpsF rpsF rpsR rpsR SFS06643.1 SFS06643.1 rplK rplK rplA rplA rplJ rplJ rplL rplL SFS01498.1 SFS01498.1 SFS11953.1 SFS11953.1 recO recO SFS12308.1 SFS12308.1 SFS12995.1 SFS12995.1 dnaG dnaG SFS15717.1 SFS15717.1 priA priA topA topA rpsB rpsB SFS16861.1 SFS16861.1 SFS16866.1 SFS16866.1 SFS16881.1 SFS16881.1 SFS16938.1 SFS16938.1 rpmF rpmF SFS15191.1 SFS15191.1 SFS18862.1 SFS18862.1 SFS18885.1 SFS18885.1 SFS18924.1 SFS18924.1 SFS18928.1 SFS18928.1 SFS18966.1 SFS18966.1 SFS18990.1 SFS18990.1 SFS19162.1 SFS19162.1 SFS19193.1 SFS19193.1 SFS19417.1 SFS19417.1 SFS19420.1 SFS19420.1 SFS18320.1 SFS18320.1 rplS rplS SFS20466.1 SFS20466.1 rpmB rpmB rplU rplU rpmA rpmA nadD nadD kptA kptA SFS20770.1 SFS20770.1 SFS20018.1 SFS20018.1 ispH ispH SFS21032.1 SFS21032.1 rpsT rpsT SFS21048.1 SFS21048.1 SFS21523.1 SFS21523.1 SFS21689.1 SFS21689.1 rplT rplT rpmI rpmI rpsO rpsO SFS22539.1 SFS22539.1 SFS22540.1 SFS22540.1 miaA miaA rimM rimM rpsP rpsP SFS22543.1 SFS22543.1 pduL pduL smc smc SFS22531.1 SFS22531.1 eutP eutP pduB pduB SFS22607.1 SFS22607.1 SFS22537.1 SFS22537.1 SFS22931.1 SFS22931.1 SFS22932.1 SFS22932.1 SFS22933.1 SFS22933.1 SFS22936.1 SFS22936.1 SFS22939.1 SFS22939.1 SFS22942.1 SFS22942.1 SFS22943.1 SFS22943.1 SFS22944.1 SFS22944.1 SFS22796.1 SFS22796.1 eutM eutM pduL-2 pduL-2 SFS22839.1 SFS22839.1 SFS22840.1 SFS22840.1 SFS22841.1 SFS22841.1 SFS22842.1 SFS22842.1 SFS22844.1 SFS22844.1 SFS22846.1 SFS22846.1 SFS22847.1 SFS22847.1 SFS22851.1 SFS22851.1 SFS22852.1 SFS22852.1 eutM-2 eutM-2 SFS23108.1 SFS23108.1 recR recR rpsE rpsE rpmD rpmD rplO rplO SFS23217.1 SFS23217.1 rpsM rpsM rpsK rpsK rpsD rpsD rplQ rplQ rplM rplM rpsI rpsI rpsJ rpsJ rplC rplC rplD rplD rplW rplW rplB rplB rpsS rpsS rplV rplV rpsC rpsC rplP rplP rpmC rpmC rpsQ rpsQ rplN rplN rplX rplX rplE rplE rpsZ rpsZ rpsH rpsH rplF rplF rplR rplR SFS23444.1 SFS23444.1 nfo nfo rpmH rpmH SFS23679.1 SFS23679.1 gyrB-2 gyrB-2 gyrA gyrA SFS23680.1 SFS23680.1 nfo-2 nfo-2 SFS23752.1 SFS23752.1 ispE ispE rplI rplI SFR83713.1 SFR83713.1 rpsL rpsL rpsG rpsG recQ recQ ubiX ubiX SFR94915.1 SFR94915.1 SFR95449.1 SFR95449.1 SFR96147.1 SFR96147.1 recN recN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SFR96468.1Hypothetical protein. (174 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (424 aa)
glgDGlucose-1-phosphate adenylyltransferase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (373 aa)
SFR85063.1Nitrogenase iron protein NifH; Belongs to the NifH/BchL/ChlL family. (259 aa)
SFR87055.1Hypothetical protein. (706 aa)
mutS2DNA mismatch repair protein MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (812 aa)
gyrBDNA gyrase subunit B. (655 aa)
SFR87936.1ATP-dependent RNA helicase SUPV3L1/SUV3. (668 aa)
SFR88350.1Putative ATPase. (439 aa)
SFR92768.1DnaD and phage-associated domain-containing protein. (483 aa)
SFR92776.1DNA replication protein DnaC. (326 aa)
SFR93219.1MgsA AAA+ ATPase C terminal. (195 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (310 aa)
SFR94227.1MutS domain V; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (649 aa)
SFR94327.1Nitrogenase iron protein NifH; Belongs to the NifH/BchL/ChlL family. (251 aa)
topBDNA topoisomerase-3; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (735 aa)
SFS01647.1Hypothetical protein. (992 aa)
SFS02071.1Phosphoenolpyruvate phosphomutase. (305 aa)
SFS03746.1Small subunit ribosomal protein S1. (269 aa)
rpsFSSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA. (95 aa)
rpsRSSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (89 aa)
SFS06643.1dCMP deaminase. (164 aa)
rplKLSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (141 aa)
rplALarge subunit ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (231 aa)
rplJLSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (166 aa)
rplLLarge subunit ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (124 aa)
SFS01498.1Putative SOS response-associated peptidase YedK; Belongs to the SOS response-associated peptidase family. (218 aa)
SFS11953.1Protein of unknown function. (433 aa)
recODNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. (216 aa)
SFS12308.1Hypothetical protein. (989 aa)
SFS12995.1Hypothetical protein. (588 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (629 aa)
SFS15717.16-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase. (188 aa)
priAReplication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (752 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (695 aa)
rpsBSSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (248 aa)
SFS16861.1DNA gyrase subunit B. (639 aa)
SFS16866.1DNA gyrase subunit A. (744 aa)
SFS16881.1DNA topoisomerase-3. (705 aa)
SFS16938.12''-aminoglycoside nucleotidyltransferase. (172 aa)
rpmFLarge subunit ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (60 aa)
SFS15191.1Uncharacterized conserved protein, DUF362 family. (364 aa)
SFS18862.1Hypothetical protein. (381 aa)
SFS18885.1Maff2 family protein. (46 aa)
SFS18924.1Replication initiator protein A (RepA) N-terminus. (283 aa)
SFS18928.1Phage DNA replication protein (predicted replicative helicase loader). (280 aa)
SFS18966.1DNA (cytosine-5)-methyltransferase 1. (303 aa)
SFS18990.1DNA topoisomerase-3. (696 aa)
SFS19162.1CHC2 zinc finger. (229 aa)
SFS19193.1DNA (cytosine-5)-methyltransferase 1. (513 aa)
SFS19417.1Protein of unknown function. (101 aa)
SFS19420.1Protein of unknown function. (455 aa)
SFS18320.1Beta-L-arabinofuranosidase, GH127. (629 aa)
rplSLarge subunit ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (115 aa)
SFS20466.1Metallo-beta-lactamase family protein. (535 aa)
rpmBLarge subunit ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (61 aa)
rplULSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (102 aa)
rpmALSU ribosomal protein L27P; Belongs to the bacterial ribosomal protein bL27 family. (96 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (215 aa)
kptAPutative RNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (179 aa)
SFS20770.1Carboxysome shell and ethanolamine utilization microcompartment protein CcmL/EutN. (181 aa)
SFS20018.1dCMP deaminase. (160 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (663 aa)
SFS21032.1Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. (316 aa)
rpsTSSU ribosomal protein S20P; Binds directly to 16S ribosomal RNA. (87 aa)
SFS21048.1Ribosomal protein L7Ae. (111 aa)
SFS21523.1CHC2 zinc finger. (214 aa)
SFS21689.1Uncharacterized conserved protein YqgV, UPF0045/DUF77 family. (98 aa)
rplTLSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa)
rpmILSU ribosomal protein L35P; Belongs to the bacterial ribosomal protein bL35 family. (65 aa)
rpsOSSU ribosomal protein S15P; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (88 aa)
SFS22539.1Carboxysome shell and ethanolamine utilization microcompartment protein CcmL/EutN. (223 aa)
SFS22540.1Ethanolamine utilization protein EutN. (87 aa)
miaAtRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (327 aa)
rimM16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (170 aa)
rpsPSSU ribosomal protein S16P; Belongs to the bacterial ribosomal protein bS16 family. (80 aa)
SFS22543.1BMC domain-containing protein. (92 aa)
pduLPutative phosphotransacetylase; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (212 aa)
smcCondensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1186 aa)
SFS22531.1Ethanolamine utilization protein EutS. (113 aa)
eutPEthanolamine utilization protein EutP; Belongs to the EutP/PduV family. (163 aa)
pduBMicrocompartment protein PduB. (264 aa)
SFS22607.1Hypothetical protein. (187 aa)
SFS22537.1BMC domain-containing protein. (92 aa)
SFS22931.1Ethanolamine utilization protein EutP. (156 aa)
SFS22932.1Ethanolamine utilization protein EutS. (130 aa)
SFS22933.1Ethanolamine utilization protein EutN. (96 aa)
SFS22936.1BMC domain-containing protein. (215 aa)
SFS22939.1BMC domain-containing protein. (105 aa)
SFS22942.1Putative phosphotransacetylase. (213 aa)
SFS22943.1Microcompartment protein PduB. (266 aa)
SFS22944.1BMC domain-containing protein. (93 aa)
SFS22796.1Hypothetical protein. (647 aa)
eutMBMC domain-containing protein. (94 aa)
pduL-2Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (228 aa)
SFS22839.1Carboxysome shell and ethanolamine utilization microcompartment protein CcmL/EutN. (229 aa)
SFS22840.1Transcriptional regulator. (213 aa)
SFS22841.1Ethanolamine utilization protein EutN. (91 aa)
SFS22842.1BMC domain-containing protein. (101 aa)
SFS22844.1Hypothetical protein. (209 aa)
SFS22846.1Ethanolamine utilization protein EutP. (165 aa)
SFS22847.1Ethanolamine utilization protein EutS. (117 aa)
SFS22851.1BMC domain-containing protein. (106 aa)
SFS22852.1BMC domain-containing protein. (98 aa)
eutM-2BMC domain-containing protein. (95 aa)
SFS23108.1Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (118 aa)
recRDNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (198 aa)
rpsESmall subunit ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (169 aa)
rpmDLarge subunit ribosomal protein L30. (60 aa)
rplOLSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (146 aa)
SFS23217.1Hypothetical protein. (87 aa)
rpsMSmall subunit ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (122 aa)
rpsKSmall subunit ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (133 aa)
rpsDSSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (197 aa)
rplQLSU ribosomal protein L17P. (178 aa)
rplMLSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa)
rpsISmall subunit ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (130 aa)
rpsJSSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (105 aa)
rplCLarge subunit ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (211 aa)
rplDLarge subunit ribosomal protein L4; Forms part of the polypeptide exit tunnel. (206 aa)
rplWLarge subunit ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (99 aa)
rplBLSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (281 aa)
rpsSSmall subunit ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (94 aa)
rplVLSU ribosomal protein L22P; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (128 aa)
rpsCSSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (218 aa)
rplPLarge subunit ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (145 aa)
rpmCLSU ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (67 aa)
rpsQSmall subunit ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (92 aa)
rplNLSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rplXLSU ribosomal protein L24P; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (101 aa)
rplELarge subunit ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa)
rpsZSmall subunit ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa)
rpsHSmall subunit ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (133 aa)
rplFLarge subunit ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (180 aa)
rplRLSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (122 aa)
SFS23444.1DNA (cytosine-5)-methyltransferase 1. (367 aa)
nfoEndonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (327 aa)
rpmHLSU ribosomal protein L34P; Belongs to the bacterial ribosomal protein bL34 family. (44 aa)
SFS23679.1Protein of unknown function. (170 aa)
gyrB-2DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (637 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (848 aa)
SFS23680.1Chromosome partitioning protein, ParB family; Belongs to the ParB family. (307 aa)
nfo-2Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (277 aa)
SFS23752.1Hypothetical protein. (407 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (298 aa)
rplILarge subunit ribosomal protein L9; Binds to the 23S rRNA. (148 aa)
SFR83713.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (452 aa)
rpsLSSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (139 aa)
rpsGSmall subunit ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
recQATP-dependent DNA helicase RecQ. (787 aa)
ubiX4-hydroxy-3-polyprenylbenzoate decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (186 aa)
SFR94915.1Recombination protein MgsA. (439 aa)
SFR95449.1DNA replication protein DnaC. (258 aa)
SFR96147.1tRNA(His) 5'-end guanylyltransferase. (254 aa)
recNDNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. (552 aa)
Your Current Organism:
Clostridium citroniae
NCBI taxonomy Id: 358743
Other names: CCUG 52203, Clostridium citroniae Warren et al. 2007, DSM 19261, [. citroniae, [Clostridium] citroniae, strain RMA 16102
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