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BAB2_0485 BAB2_0485 BAB1_0307 BAB1_0307 BAB1_0226 BAB1_0226 BAB1_0224 BAB1_0224 BAB1_0212 BAB1_0212 BAB1_0166 BAB1_0166 BAB1_0156 BAB1_0156 lspA lspA BAB1_0135 BAB1_0135 cysA cysA cysW-1 cysW-1 BAB1_0072 BAB1_0072 qoxD qoxD BAB1_1670 BAB1_1670 rbsC-2 rbsC-2 potA potA BAB1_1595 BAB1_1595 BAB1_1711 BAB1_1711 BAB1_1895 BAB1_1895 BAB1_1920 BAB1_1920 ispZ ispZ argH argH BAB1_2056 BAB1_2056 BAB1_2074 BAB1_2074 BAB1_2096 BAB1_2096 lnt lnt BAB2_0008 BAB2_0008 BAB2_0057 BAB2_0057 virB3 virB3 BAB2_0071 BAB2_0071 BAB2_0072 BAB2_0072 modB modB potA-2 potA-2 gluP gluP rbsC-5 rbsC-5 rbsC-4 rbsC-4 pntA pntA pntAB pntAB pntB pntB BAB2_0273 BAB2_0273 BAB2_0314 BAB2_0314 BAB2_0321 BAB2_0321 BAB2_0376 BAB2_0376 crcB-3 crcB-3 crcB-4 crcB-4 BAB2_0429 BAB2_0429 BAB1_0645 BAB1_0645 omp2a omp2a omp2b omp2b BAB1_0702 BAB1_0702 BAB1_0708 BAB1_0708 BAB1_0709 BAB1_0709 BAB1_0758 BAB1_0758 BAB1_0768 BAB1_0768 BAB1_0804 BAB1_0804 lolD lolD yajC yajC BAB1_0942 BAB1_0942 qacH qacH BAB1_1038 BAB1_1038 folK folK BAB1_1095 BAB1_1095 BAB1_1112 BAB1_1112 BAB1_1137 BAB1_1137 BAB1_1275 BAB1_1275 BAB1_1323 BAB1_1323 cysW-2 cysW-2 BAB2_0500 BAB2_0500 BAB2_0502 BAB2_0502 fbpC fbpC BAB2_0538 BAB2_0538 ugpE ugpE BAB2_0670 BAB2_0670 BAB2_0709 BAB2_0709 BAB2_0719 BAB2_0719 BAB2_0729 BAB2_0729 BAB2_0730 BAB2_0730 BAB2_0763 BAB2_0763 BAB2_0764 BAB2_0764 BAB2_0769 BAB2_0769 BAB2_0771 BAB2_0771 BAB2_0804 BAB2_0804 BAB2_0838 BAB2_0838 BAB2_0840 BAB2_0840 BAB2_0852 BAB2_0852 BAB2_0877 BAB2_0877 potA-3 potA-3 nosY nosY BAB2_1002 BAB2_1002 uppP uppP BAB2_1064 BAB2_1064 BAB2_1065 BAB2_1065 znuC znuC BAB2_1103 BAB2_1103 BAB2_1129 BAB2_1129 BAB1_1593 BAB1_1593 lgt lgt BAB1_1539 BAB1_1539 BAB1_1519 BAB1_1519 BAB1_1701 BAB1_1701 macB macB BAB1_1683 BAB1_1683 BAB1_1680 BAB1_1680 BAB1_1364 BAB1_1364 BAB1_1366 BAB1_1366 cbiM cbiM BAB1_1387 BAB1_1387 BAB1_1388 BAB1_1388 crcB crcB BAB1_1414 BAB1_1414 hflC hflC mraY mraY BAB1_1456 BAB1_1456 rbsC-1 rbsC-1 BAB1_0535 BAB1_0535 BAB1_0515 BAB1_0515 ubiA ubiA bacA bacA mscL mscL BAB1_0323 BAB1_0323
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BAB2_0485ATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase. (264 aa)
BAB1_0307Acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1043 aa)
BAB1_0226Substrate-binding region of ABC-type glycine betaine transport system. (304 aa)
BAB1_0224ATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase. (312 aa)
BAB1_0212RNA-binding region RNP-1 (RNA recognition motif):Binding-protein-dependent transport systems inner membrane component. (258 aa)
BAB1_0166Sodium:dicarboxylate symporter:Protein of unknown function DUF540. (237 aa)
BAB1_0156ATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase. (277 aa)
lspASignal peptidase II, family A8; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (160 aa)
BAB1_0135Conserved hypothetical protein. (112 aa)
cysAATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (359 aa)
cysW-1Binding-protein-dependent transport systems inner membrane component:NADH-plastoquinone oxidoreductase, chain 5. (288 aa)
BAB1_0072Lysine exporter protein (LYSE/YGGA). (219 aa)
qoxDProkaryotic Cytochrome C oxidase subunit IV. (121 aa)
BAB1_1670Conserved hypothetical protein. (69 aa)
rbsC-2Bacterial inner-membrane translocator:Voltage-dependent potassium channel; Belongs to the binding-protein-dependent transport system permease family. (334 aa)
potABinding-protein-dependent transport systems inner membrane component; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (381 aa)
BAB1_1595ATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase. (348 aa)
BAB1_1711Biopolymer transport protein ExbD/TolR. (150 aa)
BAB1_1895ATP/GTP-binding site motif A (P-loop):Cell divisionFtsK/SpoIIIE protein:AAA ATPase; Belongs to the FtsK/SpoIIIE/SftA family. (531 aa)
BAB1_1920Lysine exporter protein (LYSE/YGGA). (212 aa)
ispZATP/GTP-binding site motif A (P-loop):Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. (220 aa)
argHFumarate lyase:Delta crystallin. (466 aa)
BAB1_2056Bacterial inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (294 aa)
BAB1_2074FxsA cytoplasmic membrane protein. (165 aa)
BAB1_2096PTS system fructose subfamily IIA component. (133 aa)
lntApolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (532 aa)
BAB2_0008ATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase. (523 aa)
BAB2_0057Outer membrane protein OprF; The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice. This protein is essential for pathogenesis in mice but is not required for intracellular survival. (172 aa)
virB3Type IV secretory pathway, VirB3-like; The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice. (116 aa)
BAB2_0071Conserved hypothetical protein. (512 aa)
BAB2_0072CBS domain:Cytochrome b5:Sugar isomerase (SIS):KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. (333 aa)
modBBinding-protein-dependent transport systems inner membrane component:Molybdate porter; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (228 aa)
potA-2Spermidine/putrescine import ATP-binding protein PotA; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (353 aa)
gluPBacterial glucose/galactose transporter; Intake of glucose and galactose; Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family. (412 aa)
rbsC-5Bacterial inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (319 aa)
rbsC-4Bacterial inner-membrane translocator:Glucose/ribitol dehydrogenase; Belongs to the binding-protein-dependent transport system permease family. (317 aa)
pntARecA bacterial DNA recombination protein:Alanine dehydrogenase/PNT, C-terminal:Alanine dehydrogenase/PNT, N-terminal. (425 aa)
pntABAntifreeze protein, type I:Pollen allergen Poa pIX/Phl pVI, C-terminal. (139 aa)
pntBNAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (466 aa)
BAB2_0273Binding-protein-dependent transport systems inner membrane component. (221 aa)
BAB2_0314Heat resistant agglutinin 1 precursor; Belongs to the surface antigen msp4 family. (284 aa)
BAB2_0321Secretion protein, putative; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1024 aa)
BAB2_0376Bacterial inner-membrane translocator:Sodium:dicarboxylate symporter; Belongs to the binding-protein-dependent transport system permease family. (346 aa)
crcB-3Camphor resistance CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (137 aa)
crcB-4Camphor resistance CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (133 aa)
BAB2_0429Binding-protein-dependent transport systems inner membrane component:Tumour necrosis factor c/lymphotoxin-beta. (299 aa)
BAB1_0645Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (563 aa)
omp2aATP/GTP-binding site motif A (P-loop):Porin, alpha proteobacteria type; Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane. (321 aa)
omp2bATP/GTP-binding site motif A (P-loop):Porin, alpha proteobacteria type; Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane. (375 aa)
BAB1_0702Protein of unknown function DUF6:RarD protein. (306 aa)
BAB1_0708Predicted permease YjgP/YjgQ family. (362 aa)
BAB1_0709Predicted permease YjgP/YjgQ family. (402 aa)
BAB1_0758Gly-zipper_YMGG domain-containing protein; Unnamed protein product. (82 aa)
BAB1_0768Binding-protein-dependent transport systems inner membrane component:Tetracycline resistance protein. (343 aa)
BAB1_0804Polysaccharide export protein. (195 aa)
lolDATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (227 aa)
yajCYajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (113 aa)
BAB1_0942RNA-binding region RNP-1 (RNA recognition motif). (1146 aa)
qacHSmall multidrug resistance protein. (110 aa)
BAB1_1038Sulfate transporter/antisigma-factor antagonist STAS:Protein of unknown function DUF140. (391 aa)
folK7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK. (177 aa)
BAB1_1095Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. (123 aa)
BAB1_1112Acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1029 aa)
BAB1_1137Conserved hypothetical protein. (458 aa)
BAB1_1275Rhomboid-like protein. (253 aa)
BAB1_1323Protein of unknown function DUF81. (261 aa)
cysW-2Binding-protein-dependent transport systems inner membrane component. (276 aa)
BAB2_0500ATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase:Glycine betaine/L-proline transport ATP-binding subunit. (377 aa)
BAB2_0502ATP/GTP-binding site motif A (P-loop):Substrate-binding region of ABC-type glycine betaine transport system. (288 aa)
fbpCUridine kinase:ATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system. (353 aa)
BAB2_0538NAD binding site; Belongs to the ABC transporter superfamily. (367 aa)
ugpEBinding-protein-dependent transport systems inner membrane component:Aromatic amino acid permease; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Probably responsible for the translocation of the substrate across the membrane (By similarity). (282 aa)
BAB2_0670Rhodopsin-like GPCR superfamily:ATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase. (520 aa)
BAB2_0709ATP/GTP-binding site motif A (P-loop):Cell divisionFtsK/SpoIIIE protein:Proline-rich extensin:AAA ATPase; Belongs to the FtsK/SpoIIIE/SftA family. (819 aa)
BAB2_0719CD9/CD37/CD63 antigen:Binding-protein-dependent transport systems inner membrane component:Delayed-early response protein/equ. (279 aa)
BAB2_0729Bacterial regulatory protein LysR, HTH motif:ABC transporter, transmembrane region:ATP/GTP-binding site motif A (P-loop):Bloo. (560 aa)
BAB2_0730ABC transporter, transmembrane region:ATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase. (541 aa)
BAB2_0763ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal:Bacterial sensor protein, C-term. (474 aa)
BAB2_0764Gram-negative bacterial RTX secretion protein D:Secretion protein HlyD. (349 aa)
BAB2_0769Binding-protein-dependent transport systems inner membrane component. (272 aa)
BAB2_0771ABC transporter, family 2:Polycystic kidney disease type 1 protein. (377 aa)
BAB2_0804Fucose synthetase family protein. (415 aa)
BAB2_0838Iron permease FTR1. (278 aa)
BAB2_0840Membrane antigen, putative; Belongs to the UPF0423 family. (182 aa)
BAB2_0852Cl-channel, voltage gated:Sodium:dicarboxylate symporter. (451 aa)
BAB2_0877Binding-protein-dependent transport systems inner membrane component. (412 aa)
potA-3Spermidine/putrescine import ATP-binding protein PotA; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (355 aa)
nosYNitrous-oxide reductase, nosY component. (276 aa)
BAB2_1002NADH-ubiquinone oxidoreductase 39 kd subunit. (328 aa)
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (268 aa)
BAB2_1064Binding-protein-dependent transport systems inner membrane component:Prenyl group binding site (CAAX box):Bacterial general s. (271 aa)
BAB2_1065ATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase:TOBE domain. (358 aa)
znuCATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (298 aa)
BAB2_1103OmpA/MotB domain. (366 aa)
BAB2_1129Basic helix-loop-helix dimerization domain bHLH:DNA topoisomerase II:Amino acid/polyamine transporter, family I. (497 aa)
BAB1_1593Substrate-binding region of ABC-type glycine betaine transport system. (322 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (281 aa)
BAB1_1539ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal:Bacterial sensor protein, C-term. (432 aa)
BAB1_1519Pyrokinin:Potassium channel TASK:Cation transporter; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family. (466 aa)
BAB1_1701Heat resistant agglutinin 1 precursor. (274 aa)
macBATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase:Phosphoribulokinase; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (381 aa)
BAB1_1683Conserved hypothetical protein. (266 aa)
BAB1_1680Biopolymer transport protein ExbD/TolR. (164 aa)
BAB1_1364ATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase. (258 aa)
BAB1_1366Periplasmic binding protein. (279 aa)
cbiMCobalamin (vitamin B12) biosynthesis CbiM protein. (211 aa)
BAB1_1387Cobalt transport protein. (254 aa)
BAB1_1388ATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase; Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity). (239 aa)
crcBCamphor resistance CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (129 aa)
BAB1_1414Conserved hypothetical protein. (61 aa)
hflCBand 7 protein; HflC and HflK could regulate a protease. (300 aa)
mraYGlycosyl transferase, family 4:Phospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa)
BAB1_1456Beta-lactamase, class A:Penicillin-binding protein, transpeptidase domain:ATP/GTP-binding site motif A (P-loop):Penicillin-bi. (607 aa)
rbsC-1Tetracycline resistance protein TetB:Bacterial inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family. (333 aa)
BAB1_0535Glycosyl transferase, family 4. (335 aa)
BAB1_0515Cl-channel, voltage gated. (568 aa)
ubiAUbiA prenyltransferase:4-hydroxybenzoate polyprenyl transferase, proteobacterial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (333 aa)
bacABacteroid development protein BacA. (415 aa)
mscLLarge-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (138 aa)
BAB1_0323Acriflavin resistance protein:Hydrophobe/amphiphile efflux-1 HAE1. (1051 aa)
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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