STRINGSTRING
CUN53618.1 CUN53618.1 CUO50963.1 CUO50963.1 CUO48850.1 CUO48850.1 hisH1 hisH1 hisF hisF CUO36763.1 CUO36763.1 hisA hisA CUO33939.1 CUO33939.1 CUO23724.1 CUO23724.1 CUO11121.1 CUO11121.1 hisK_2 hisK_2 CUO03763.1 CUO03763.1 hisC hisC hisE hisE hisB hisB hisD hisD hisG hisG hisZ hisZ CUN80028.1 CUN80028.1 CUN72971.1 CUN72971.1 hisK_1 hisK_1 pat pat calB calB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CUN53618.1Predicted P-loop ATPase. (744 aa)
CUO50963.1Transposase IS116/IS110/IS902 family. (402 aa)
CUO48850.1Transposase IS116/IS110/IS902 family. (391 aa)
hisH1Imidazole glycerol phosphate synthase subunit HisH 1; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (201 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (253 aa)
CUO36763.1Flavodoxin. (156 aa)
hisA1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)m ethylideneamino] imidazole-4-carboxamide isomerase; Belongs to the HisA/HisF family. (258 aa)
CUO33939.1Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (275 aa)
CUO23724.1Transposase. (221 aa)
CUO11121.1PEGA domain. (411 aa)
hisK_2Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (263 aa)
CUO03763.1Regulator of competence-specific genes. (105 aa)
hisCHistidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (352 aa)
hisEPhosphoribosyl-ATP pyrophosphatase; In the C-terminal section; belongs to the PRA-PH family. (431 aa)
hisBHistidine biosynthesis bifunctional protein hisB. (195 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (222 aa)
hisZATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (396 aa)
CUN80028.1Uncharacterised protein. (202 aa)
CUN72971.1Transposase IS116/IS110/IS902 family. (392 aa)
hisK_1Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (278 aa)
patPutative phenylalanine aminotransferase. (359 aa)
calBConiferyl aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (459 aa)
Your Current Organism:
Roseburia inulinivorans
NCBI taxonomy Id: 360807
Other names: DSM 16841, NCIMB 14030, R. inulinivorans, Roseburia inulinivorans Duncan et al. 2006, butyrate-producing bacterium A2-194, butyrate-producing bacterium L1-83, strain A2-194
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