(48 nodes) Negative regulation of organelle organization network (Trichuris trichiura)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	A0A077Z6U1	Centromere. (825 aa)
	A0A077Z591	Uncharacterized protein. (184 aa)
	A0A077Z401	Tropomodulin family protein. (433 aa)
	A0A077Z314	Calmodulin regulated spectrin associated protein. (1041 aa)
	A0A077Z2A7	Vacuole membrane protein transmembrane protein. (483 aa)
	A0A077Z1R9	Ank 2 and ZU5 and Ank domain containing protein. (1630 aa)
	A0A077Z1B7	DNA helicase; Belongs to the MCM family. (904 aa)
	A0A077Z183	Ank 2 and KN motif domain containing protein. (1694 aa)
	A0A077Z0N8	POT1PC domain-containing protein. (457 aa)
	A0A077Z0D8	LsmAD domain-containing protein. (926 aa)
	A0A077YZ14	Protein flightless 1. (1283 aa)
	A0A077YYX8	Fasciculation and elongation protein zeta 2. (429 aa)
	KATNA1	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (500 aa)
	A0A077YYE8	Ras C3 botulinum toxin substrate 1. (206 aa)
	A0A077YYE4	Growth hormone inducible transmembrane protein. (369 aa)
	A0A077YX52	Profilin; Belongs to the profilin family. (135 aa)
	A0A077YX40	Protein sma d protein sma c protein sma b. (4090 aa)
	A0A077YX39	26S proteasome non-ATPase regulatory subunit 10. (229 aa)
	A0A077YWX6	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (276 aa)
	A0A077YWV9	Serine:threonine protein kinase MAK. (538 aa)
	A0A077YWC5	Pkinase domain containing protein. (827 aa)
	A0A077YVX9	Unc protein. (627 aa)
	A0A077YVU9	Twinfilin 1. (381 aa)
	A0A077Z645	Adducin protein 1. (547 aa)
	A0A077Z6Z1	Spectrin beta chain; Belongs to the spectrin family. (2252 aa)
	A0A077Z7Z8	Netrin receptor UNC5B. (792 aa)
	A0A077Z9E1	Uncharacterized protein. (252 aa)
	A0A077Z9N3	F box:WD repeat containing protein 1A. (444 aa)
	A0A077ZAI3	Transmembrane protein C2orf18. (395 aa)
	A0A077ZAP9	WAPL domain containing protein. (359 aa)
	A0A077ZB52	Protein phosphatase 1 regulatory subunit 7. (321 aa)
	A0A077ZBA4	Mitotic checkpoint protein BUB3. (755 aa)
	A0A077ZBH6	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (279 aa)
	A0A077ZD25	DNA repair protein XRCC1. (380 aa)
	A0A077ZD85	Transmembrane protein 39A. (407 aa)
	A0A077ZEG5	Mitotic spindle assembly checkpoint protein MAD2A. (157 aa)
	A0A077ZF35	Poly [ADP-ribose] polymerase. (1196 aa)
	A0A077ZFV4	DEK C and DSPc domain containing protein. (351 aa)
	A0A077ZGF5	5' 3' exoribonuclease 1. (592 aa)
	A0A077ZGT9	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (630 aa)
	A0A077ZHH2	VHP and Gelsolin domain containing protein. (559 aa)
	A0A077ZHZ7	F box:WD repeat containing protein 7. (510 aa)
	A0A077ZID8	Uncharacterized protein. (495 aa)
	A0A077ZKN5	Cofilin ADF domain containing protein; Belongs to the actin-binding proteins ADF family. GMF subfamily. (109 aa)
	A0A077ZKV6	DSPc domain containing protein. (455 aa)
	A0A077ZMJ2	Smith Magenis syndrome chromosomal region. (607 aa)
	A0A077ZMW9	Adenomatous polyposis coli protein. (1026 aa)
	A0A077ZRC8	WAPL domain containing protein. (116 aa)

Your Current Organism:

Trichuris trichiura

NCBI taxonomy Id: 36087
Other names: T. trichiura, human whipworm

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A077YVU9	A0A077YWX6	A0A077YVU9	A0A077YWX6	Twinfilin 1.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.942
A0A077YVU9	A0A077YX39	A0A077YVU9	A0A077YX39	Twinfilin 1.	26S proteasome non-ATPase regulatory subunit 10.	0.433
A0A077YVU9	A0A077YX52	A0A077YVU9	A0A077YX52	Twinfilin 1.	Profilin; Belongs to the profilin family.	0.606
A0A077YVU9	A0A077YYE8	A0A077YVU9	A0A077YYE8	Twinfilin 1.	Ras C3 botulinum toxin substrate 1.	0.684
A0A077YVU9	A0A077Z183	A0A077YVU9	A0A077Z183	Twinfilin 1.	Ank 2 and KN motif domain containing protein.	0.556
A0A077YVU9	A0A077Z1R9	A0A077YVU9	A0A077Z1R9	Twinfilin 1.	Ank 2 and ZU5 and Ank domain containing protein.	0.402
A0A077YVU9	A0A077Z401	A0A077YVU9	A0A077Z401	Twinfilin 1.	Tropomodulin family protein.	0.760
A0A077YVU9	A0A077Z9E1	A0A077YVU9	A0A077Z9E1	Twinfilin 1.	Uncharacterized protein.	0.622
A0A077YVU9	A0A077ZBH6	A0A077YVU9	A0A077ZBH6	Twinfilin 1.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.976
A0A077YVU9	A0A077ZF35	A0A077YVU9	A0A077ZF35	Twinfilin 1.	Poly [ADP-ribose] polymerase.	0.402
A0A077YVU9	A0A077ZHH2	A0A077YVU9	A0A077ZHH2	Twinfilin 1.	VHP and Gelsolin domain containing protein.	0.803
A0A077YVU9	A0A077ZKN5	A0A077YVU9	A0A077ZKN5	Twinfilin 1.	Cofilin ADF domain containing protein; Belongs to the actin-binding proteins ADF family. GMF subfamily.	0.567
A0A077YVX9	A0A077YYE8	A0A077YVX9	A0A077YYE8	Unc protein.	Ras C3 botulinum toxin substrate 1.	0.519
A0A077YVX9	A0A077YZ14	A0A077YVX9	A0A077YZ14	Unc protein.	Protein flightless 1.	0.615
A0A077YVX9	A0A077Z7Z8	A0A077YVX9	A0A077Z7Z8	Unc protein.	Netrin receptor UNC5B.	0.893
A0A077YVX9	A0A077ZB52	A0A077YVX9	A0A077ZB52	Unc protein.	Protein phosphatase 1 regulatory subunit 7.	0.615
A0A077YWC5	A0A077Z1B7	A0A077YWC5	A0A077Z1B7	Pkinase domain containing protein.	DNA helicase; Belongs to the MCM family.	0.620
A0A077YWC5	A0A077ZBA4	A0A077YWC5	A0A077ZBA4	Pkinase domain containing protein.	Mitotic checkpoint protein BUB3.	0.503
A0A077YWC5	A0A077ZEG5	A0A077YWC5	A0A077ZEG5	Pkinase domain containing protein.	Mitotic spindle assembly checkpoint protein MAD2A.	0.989
A0A077YWC5	A0A077ZGT9	A0A077YWC5	A0A077ZGT9	Pkinase domain containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.788