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| | rdgC-3 | Putative phage recombinase; May be involved in recombination; Belongs to the RdgC family. (300 aa) |
| | gidA | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (637 aa) |
| | gidB | Glucose inhibited division protein B; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (224 aa) |
| | nusG | Transcription antitermination protein; Participates in transcription elongation, termination and antitermination. (177 aa) |
| | rpoB | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1378 aa) |
| | rpoC | DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1413 aa) |
| | rpoA | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (328 aa) |
| | uvrA | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (952 aa) |
| | ssb | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (166 aa) |
| | BAV0087 | Putative lipopolysaccharide biosynthesis protein. (647 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (596 aa) |
| | BAV0116 | Putative endonuclease/exonuclease/phosphatase family protein. (286 aa) |
| | xerC | Tyrosine recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (325 aa) |
| | cca | tRNA nucleotidyltransferase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (355 aa) |
| | rhlE | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (592 aa) |
| | ung | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (252 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (311 aa) |
| | BAV0208 | Putative radical SAM protein; Start codon not provided. (442 aa) |
| | rsmB | Ribosomal RNA small subunit methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (442 aa) |
| | trmL | Putative RNA methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. (156 aa) |
| | BAV0267 | Conserved hypothetical protein. (158 aa) |
| | BAV0358 | Putative restriction endonuclease (partial). (105 aa) |
| | BAV0360 | Putative type I restriction-modification system specificity determinant (partial). (48 aa) |
| | BAV0365 | Conserved hypothetical phage protein. (258 aa) |
| | BAV0368 | Conserved hypothetical phage protein; Start codon not provided. (522 aa) |
| | traR | Putative nickase. (331 aa) |
| | BAV0381 | Putative plasmid-related protein (pseudogene). (336 aa) |
| | BAV0384 | Transposase. (104 aa) |
| | BAV0385 | Restriction-modification system, endonuclease subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1044 aa) |
| | BAV0386 | Restriction modification system, specificity subunit. (412 aa) |
| | BAV0387 | Restriction-modification system, modification (methylase) subunit; Start codon not provided. (924 aa) |
| | BAV0391 | Putative integrase (pseudogene); Prophage 1. Shares few genes (on the right arm) with the Bordetella phage that undergoes tropism switching; Belongs to the 'phage' integrase family. (344 aa) |
| | rdgC-2 | Putative phage-related recombination associated protein; May be involved in recombination; Belongs to the RdgC family. (300 aa) |
| | recT | Phage recombination protein. (343 aa) |
| | BAV0399 | Phage-related exonuclease; Also similar to the C-terminal region of Escherichia coli exodeoxyribonuclease VIII, recE; length 866 aa; id=37.4; ungapped id=41.1; E()=1.5e-25; 278 aa overlap; query 14-280 aa; subject 597-860 aa. (284 aa) |
| | BAV0403 | Phage-related protein. (87 aa) |
| | BAV0414 | Hypothetical phage protein. (232 aa) |
| | BAV0415 | Phage-related protein. (123 aa) |
| | yggH | tRNA(guanine-n(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (256 aa) |
| | BAV0471 | Rhodanese-like protein; Belongs to the UPF0176 family. (242 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (691 aa) |
| | mutM | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (275 aa) |
| | hsdR | Type I restriction enzyme EcoR124II R protein; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1033 aa) |
| | hsdS | Type i restriction enzyme EcoR124II specificity protein. (406 aa) |
| | hsdM | Type i restriction enzyme EcoR124II M protein. (519 aa) |
| | BAV0547 | Putative phage-related protein. (76 aa) |
| | BAV0564 | Conserved hypothetical protein. (206 aa) |
| | nusB | N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (156 aa) |
| | fecI | Probable RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (231 aa) |
| | dbpA | ATP-independent RNA helicase; Start codon not provided; Belongs to the DEAD box helicase family. (462 aa) |
| | ksgA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (262 aa) |
| | glyS | glycyl-tRNA synthetase beta chain. (711 aa) |
| | glyQ | glycyl-tRNA synthetase alpha chain. (301 aa) |
| | pcnB | poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (452 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (312 aa) |
| | mutL | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (621 aa) |
| | BAV0732 | Conserved hypothetical protein. (177 aa) |
| | BAV0806 | Putative ECF sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (174 aa) |
| | miaB | Putative nucleic acid binding protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (475 aa) |
| | ybeY | Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (161 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (378 aa) |
| | BAV0862 | Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (244 aa) |
| | BAV0893 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (341 aa) |
| | xerD | Tyrosine recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (314 aa) |
| | BAV0905 | Putative regulatory protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (162 aa) |
| | BAV0912 | Conserved hypothetical protein. (883 aa) |
| | BAV0913 | Putative nuclease/helicase; Belongs to the helicase family. UvrD subfamily. (1107 aa) |
| | dnaX | DNA polymerase III subunit Tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (646 aa) |
| | recR | Recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (202 aa) |
| | BAV0929 | Conserved hypothetical protein. (197 aa) |
| | rrmJ | Ribosomal RNA large subunit methyltransferase j; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (219 aa) |
| | mfd | Transcription-repair coupling factor; Start codon not provided. (1145 aa) |
| | BAV1067 | Putative acetyltransferase. (423 aa) |
| | smc | Putative chromosome partition protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1198 aa) |
| | ligA | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (695 aa) |
| | BAV1074 | BolA-like protein; Also similar to BAV3311 (37.6 38d); Belongs to the BolA/IbaG family. (89 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (211 aa) |
| | rne | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1015 aa) |
| | rluC | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (319 aa) |
| | BAV1110 | Probable hydrolase. (218 aa) |
| | rpoE | RNA polymerase sigma-E factor; Belongs to the sigma-70 factor family. ECF subfamily. (199 aa) |
| | rnc | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (251 aa) |
| | recO | DNA repair protein; Involved in DNA repair and RecF pathway recombination. (195 aa) |
| | holC | DNA polymerase III, chi subunit. (145 aa) |
| | BAV1176 | Putative methylase; Belongs to the methyltransferase superfamily. (535 aa) |
| | fecI-2 | RNA polymerase ECF-family sigma factor; Start codon not provided; Belongs to the sigma-70 factor family. ECF subfamily. (169 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (440 aa) |
| | rluD | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (320 aa) |
| | BAV1258 | Putative O-antigen acetylase (pseudogene). (149 aa) |
| | BAV1280 | Putative phage integrase; Belongs to the 'phage' integrase family. (415 aa) |
| | BAV1283 | Putative phage methyltransferase. (344 aa) |
| | BAV1306 | Putative phage protein; No significant database matches. (232 aa) |
| | BAV1307 | Putative phage endonuclease. (123 aa) |
| | BAV1312A | Putative phage protein. (84 aa) |
| | gyrA | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (883 aa) |
| | ihfB | Integration host factor beta-subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (119 aa) |
| | BAV1360 | Putative exported protein. (129 aa) |
| | BAV1370 | Putative radical SAM protein. (528 aa) |
| | orn | Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (181 aa) |
| | paaX | Phenylacetic acid degradation operon negative regulatory protein. (307 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (650 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (953 aa) |
| | BAV1414 | Putative S-adenosyl-l-methionine transferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (483 aa) |
| | uvrD | DNA helicase II. (750 aa) |
| | BAV1418 | ABC transporter ATP-binding protein; Start codon not provided. (640 aa) |
| | prmB | Putative adenine-specific methylase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. (296 aa) |
| | BAV1423 | Putative phage integrase; Start codon not provided; Belongs to the 'phage' integrase family. (372 aa) |
| | recT-2 | Phage recombination protein. (343 aa) |
| | BAV1425 | Phage protein. (284 aa) |
| | BAV1429 | Putative phage protein; Hypothetical gene not on same strand as others in the region. (87 aa) |
| | BAV1447 | Phage protein. (217 aa) |
| | BAV1457 | Phage protein. (127 aa) |
| | BAV1460 | Putative terminase, large subunit. (575 aa) |
| | BAV1487 | Conserved hypothetical protein. (99 aa) |
| | lexA | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (213 aa) |
| | uvrB | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (676 aa) |
| | lysS | lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (504 aa) |
| | recJ | single-stranded-DNA-specific exonuclease; Start codon not provided. (568 aa) |
| | BAV1524 | Putative deoxyribonuclease. (266 aa) |
| | BAV1526 | Putative membrane protein. (192 aa) |
| | BAV1540 | Radical SAM protein; Belongs to the radical SAM superfamily. RlmN family. (351 aa) |
| | BAV1590 | Putative DNA photolyase; Start codon not provided. (538 aa) |
| | cho | Excinuclease; Start codon not provided. (301 aa) |
| | BAV1607 | Putative phage excisionase. (138 aa) |
| | BAV1612 | Conserved hypothetical protein. (244 aa) |
| | BAV1618 | Conserved hypothetical protein. (283 aa) |
| | BAV1629 | Conserved hypothetical protein. (168 aa) |
| | xthA | Exodeoxyribonuclease III. (261 aa) |
| | rluF | Ribosomal large subunit pseudouridine synthase F (pseudouridylate synthase); Belongs to the pseudouridine synthase RsuA family. (243 aa) |
| | fliA | RNA polymerase sigma factor for flagellar operon; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (244 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (202 aa) |
| | BAV1749 | Putative RNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (257 aa) |
| | holB | DNA polymerase III, delta' subunit. (347 aa) |
| | BAV1766 | Putative deoxyribonuclease. (256 aa) |
| | BAV1790 | Putative cointegrate resolution protein. (354 aa) |
| | BAV1791 | Integrase; Belongs to the 'phage' integrase family. (370 aa) |
| | BAV1804 | Putative lipoprotein; No significant database matches. (659 aa) |
| | BAV1810 | Conserved hypothetical protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (537 aa) |
| | BAV1825 | Conserved hypothetical protein. (379 aa) |
| | BAV1842 | RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (163 aa) |
| | BAV1857 | Putative signaling protein (pseudogene). (74 aa) |
| | recG | ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (684 aa) |
| | rph | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (244 aa) |
| | BAV1937 | Conserved hypothetical protein. (310 aa) |
| | BAV1948 | SapC-related protein. (258 aa) |
| | rpoZ | DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (67 aa) |
| | BAV1971 | Conserved hypothetical protein; Start codon not provided. (287 aa) |
| | rumA | 23s rRNA (uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (476 aa) |
| | BAV1978 | Conserved hypothetical protein. (259 aa) |
| | gcp | Probable O-sialoglycoprotein endopeptidase (glycoprotease); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (345 aa) |
| | BAV1992 | ABC transporter, ATP-binding protein; Start codon not provided. (534 aa) |
| | BAV1994 | Putative zinc-binding cytidine/deoxycytidylate deaminase; Start codon not provided. (157 aa) |
| | BAV2004 | Putative exonuclease. (371 aa) |
| | BAV2012 | Conserved hypothetical protein. (173 aa) |
| | BAV2028 | Conserved hypothetical protein. (432 aa) |
| | dnaE2 | Putative DNA polymerase III alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1048 aa) |
| | dinB | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (360 aa) |
| | BAV2058 | Putative endonuclease; Start codon not provided. (243 aa) |
| | ihfA | Integration host factor alpha-subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (116 aa) |
| | pheT | phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (804 aa) |
| | pheS | phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (340 aa) |
| | xseA | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (452 aa) |
| | rlmB | Putative tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. (246 aa) |
| | rnr | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (823 aa) |
| | BAV2125 | Conserved hypothetical protein. (201 aa) |
| | trmU | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (370 aa) |
| | dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (457 aa) |
| | priB | Putative primosomal replication protein; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family. (107 aa) |
| | xseB | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (78 aa) |
| | rlmH | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (156 aa) |
| | BAV2215 | DNA-3-methyladenine glycosylase. (208 aa) |
| | BAV2217 | Putative methylated-DNA--protein-cysteine methyltransferase; Similar to the C-terminal region of Escherichia coli AdA regulatory protein; similar to the C-terminal region of BAV3120, Ada,(45.399 38d.). (184 aa) |
| | BAV2223 | Conserved hypothetical protein (pseudogene). (245 aa) |
| | cafA | Ribonuclease G. (487 aa) |
| | dnaE | DNA polymerase III alpha subunit; Similar to BAV2029 (30.755 38d.). (1163 aa) |
| | hrpA | ATP-dependent helicase. (1292 aa) |
| | BAV2247 | Conserved hypothetical protein; Start codon not provided. (414 aa) |
| | BAV2249 | Putative DNA-3-methyladenine glycosylase; Belongs to the DNA glycosylase MPG family. (230 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (267 aa) |
| | dusA | tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (327 aa) |
| | recA | RecA protein (recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (353 aa) |
| | rdgC | Recombination associated protein; May be involved in recombination; Belongs to the RdgC family. (300 aa) |
| | rpoD | RNA polymerase sigma factor 70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (726 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (674 aa) |
| | hisS | histidyl-tRNA synthetase. (428 aa) |
| | rlmN | Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (382 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (961 aa) |
| | trmD | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (270 aa) |
| | rimM | 16S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (190 aa) |
| | BAV2355 | Conserved hypothetical protein; Belongs to the sulfur carrier protein TusA family. (83 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (873 aa) |
| | parC | Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (772 aa) |
| | parE | Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (670 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (418 aa) |
| | queH | Conserved hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (224 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (904 aa) |
| | truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (244 aa) |
| | rbfA | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (132 aa) |
| | nusA | Transcription elongation protein (N utilization substance protein); Participates in both transcription termination and antitermination. (492 aa) |
| | rluB | Ribosomal large subunit pseudouridine synthase B; This CDS is extended at the C-terminus end relative to its Escherichia coli orthologue; Belongs to the pseudouridine synthase RsuA family. (457 aa) |
| | radA | DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (435 aa) |
| | BAV2431 | Conserved hypothetical protein. (79 aa) |
| | uvrC | Excinuclease ABC, subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (577 aa) |
| | leuS | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (885 aa) |
| | holA | DNA polymerase III, delta subunit. (349 aa) |
| | BAV2508 | Putative exonuclease. (193 aa) |
| | BAV2543 | Nuclease. (182 aa) |
| | BAV2545 | DNA helicase. (685 aa) |
| | mesJ | tRNAIle-lysidine synthetase (putative cell cycle protein); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. (341 aa) |
| | alkA | DNA-3-methyladenine glycosylase. (214 aa) |
| | cysS | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (483 aa) |
| | lasT | Putative tRNA/rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (267 aa) |
| | mutS | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (875 aa) |
| | BAV2596 | Conserved hypothetical protein; Belongs to the SUA5 family. (208 aa) |
| | BAV2663 | Conserved hypothetical protein. (194 aa) |
| | pnp | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (718 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (449 aa) |
| | BAV2692 | Putative ATPase. (459 aa) |
| | BAV2697 | Conserved hypothetical protein. (222 aa) |
| | dnaJ | Chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK a [...] (373 aa) |
| | recN | DNA repair protein; May be involved in recombinational repair of damaged DNA. (550 aa) |
| | rhlE-2 | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (477 aa) |
| | dusB | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. (341 aa) |
| | ruvC | Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (181 aa) |
| | ruvA | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (190 aa) |
| | ruvB | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (357 aa) |
| | recQ | ATP-dependent DNA helicase. (606 aa) |
| | glnS | glutaminyl-tRNA synthetase. (586 aa) |
| | BAV2808 | Putative excinuclease ABC subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (1900 aa) |
| | BAV2811 | Conserved hypothetical protein. (269 aa) |
| | tag | DNA-3-methyladenine glycosylase. (200 aa) |
| | mnmC | Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family. (614 aa) |
| | mraW | S-adenosyl-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (355 aa) |
| | uup | ABC transporter, ATP-binding protein. (597 aa) |
| | BAV2891 | Conserved hypothetical protein. (92 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (576 aa) |
| | dnaQ | DNA polymerase III, epsilon chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (243 aa) |
| | rnhA | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (153 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (409 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (467 aa) |
| | nrdA | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (970 aa) |
| | nrdB | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (394 aa) |
| | BAV3002 | Putative ribonuclease. (628 aa) |
| | apaH | Diadenosine-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (278 aa) |
| | yqgF | Putative holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (131 aa) |
| | BAV3038 | Putative NUDIX hydrolase; Belongs to the Nudix hydrolase family. (321 aa) |
| | mutY | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (355 aa) |
| | ada | Ada regulatory protein (methylated-dna--protein-cysteine methyltransferase); Similar over its C-terminal region to BAV2217 (45.399 38d.). (358 aa) |
| | alkB | Alkylated DNA repair protein. (213 aa) |
| | hurI | Heme uptake RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily. (171 aa) |
| | selA | selenocysteinyl-tRNA(SeC) synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (467 aa) |
| | ogt | methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (185 aa) |
| | BAV3162 | Conserved hypothetical protein; Belongs to the UPF0102 family. (145 aa) |
| | crc | Catabolite repression control protein. (260 aa) |
| | rep | ATP-dependent DNA helicase; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (684 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (682 aa) |
| | ttcA | Conserved hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (315 aa) |
| | apaG | Conserved hypothetical protein. (124 aa) |
| | rpoH | RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (307 aa) |
| | BAV3290 | Conserved hypothetical protein. (241 aa) |
| | BAV3327 | Conserved hypothetical protein. (258 aa) |
| | BAV3336 | Conserved hypothetical protein. (464 aa) |
| | rhlE-3 | Putative ATP-dependent RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (477 aa) |
| | rpoN | RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (473 aa) |
| | argS | arginyl-tRNA synthetase. (561 aa) |
| | gluQ | Putative glutamyl-tRNA synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (291 aa) |
| | topB | DNA topoisomerase III. (878 aa) |
| | rtcB | Conserved hypothetical protein. (408 aa) |
| | gyrB | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (817 aa) |
| | dnaN | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] (371 aa) |
| | dnaA | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (483 aa) |
| | rnpA | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (120 aa) |
| | trmE | Probable tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (450 aa) |
