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ACQ69497.1 ACQ69497.1 murC murC ACQ69875.1 ACQ69875.1 murA murA murA-2 murA-2 ACQ70301.1 ACQ70301.1 murE murE glmM glmM glmU glmU murB murB lysA lysA ACQ71670.1 ACQ71670.1 ACQ71718.1 ACQ71718.1 ACQ71747.1 ACQ71747.1 murF murF mraY mraY murD murD murG murG ACQ71752.1 ACQ71752.1 murE-2 murE-2 ddl ddl
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ACQ69497.1PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: bce:BC4270 penicillin-binding protein. (687 aa)
murCUDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (435 aa)
ACQ69875.1PFAM: glycosyl transferase family 4; KEGG: bcb:BCB4264_A5322 glycosyl transferase, group 4 family protein. (350 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (433 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (418 aa)
ACQ70301.1TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: sat:SYN_01113 UDP-N-acetyl-D-galactosamine 6-dehydrogenase. (441 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. (485 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (452 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (451 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (306 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (430 aa)
ACQ71670.1PFAM: cell cycle protein; KEGG: bcy:Bcer98_0919 cell cycle protein; Belongs to the SEDS family. (388 aa)
ACQ71718.1PFAM: cell cycle protein; KEGG: bsu:BSU14850 cell-division protein; Belongs to the SEDS family. (411 aa)
ACQ71747.1Peptidoglycan glycosyltransferase; KEGG: bsu:BSU15160 penicillin-binding protein 2B; PFAM: penicillin-binding protein transpeptidase; PASTA domain containing protein; Penicillin-binding protein dimerisation domain; SMART: PASTA domain containing protein. (715 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (434 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (319 aa)
murDUDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (445 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (358 aa)
ACQ71752.1PFAM: Polypeptide-transport-associated domain protein FtsQ-type; KEGG: bsu:BSU15240 cell-division initiation protein. (256 aa)
murE-2UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. (492 aa)
ddlD-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (308 aa)
Your Current Organism:
Exiguobacterium sp. AT1b
NCBI taxonomy Id: 360911
Other names: E. sp. AT1b
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