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| | cmk | TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: bsu:BSU22890 cytidylate kinase. (224 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (387 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (351 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (416 aa) |
| | dinG | DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease. (936 aa) |
| | ACQ71937.1 | TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region; KEGG: bcy:Bcer98_1269 primosome, DnaD subunit. (194 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (172 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (381 aa) |
| | queA | S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (352 aa) |
| | nadA | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (359 aa) |
| | ACQ71605.1 | KEGG: bsu:BSU27860 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. (289 aa) |
| | ACQ71604.1 | PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: bsu:BSU27870 L-aspartate oxidase. (477 aa) |
| | ACQ71568.1 | FolC bifunctional protein; KEGG: bsu:BSU28080 folyl-polyglutamate synthetase; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein. (400 aa) |
| | hemL2 | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bca:BCE_4552 glutamate-1-semialdehyde aminotransferase. (434 aa) |
| | ACQ71561.1 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bcy:Bcer98_3178 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (326 aa) |
| | ACQ71560.1 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (210 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (305 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (448 aa) |
| | ACQ71490.1 | PFAM: PHP domain protein; SMART: DNA polymerase X; phosphoesterase PHP domain protein; Helix-hairpin-helix DNA-binding class 1; KEGG: bcz:BCZK4297 hypothetical protein. (564 aa) |
| | ACQ71443.1 | PFAM: 3-demethylubiquinone-9 3-methyltransferase; Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bcr:BCAH187_A4779 hypothetical protein. (137 aa) |
| | ACQ71440.1 | Metal dependent phosphohydrolase; KEGG: bsu:BSU25630 hypothetical protein; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region. (185 aa) |
| | nadD | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (189 aa) |
| | ACQ71617.1 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (729 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (261 aa) |
| | ACQ71386.1 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (464 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (309 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (349 aa) |
| | dinB | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (363 aa) |
| | ACQ71347.1 | TIGRFAM: iron-sulfur cluster binding protein; PFAM: domain of unknown function DUF1730; KEGG: bce:BC0544 iron-sulfur cluster-binding protein. (382 aa) |
| | hemL1 | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bcr:BCAH187_A0587 glutamate-1-semialdehyde-2,1-aminomutase. (432 aa) |
| | ACQ71296.1 | TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: bsu:BSU30830 menaquinone-specific isochorismate synthase. (462 aa) |
| | ACQ71264.1 | KEGG: bha:BH0320 uridine kinase. (196 aa) |
| | ACQ71222.1 | NAD-dependent epimerase/dehydratase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (249 aa) |
| | ACQ71181.1 | PFAM: GCN5-related N-acetyltransferase; KEGG: csa:Csal_2448 GCN5-related N-acetyltransferase. (142 aa) |
| | ACQ71171.1 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (454 aa) |
| | purD | KEGG: bcu:BCAH820_0331 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; ATP-grasp domain protein; Belongs to the GARS family. (417 aa) |
| | purH | KEGG: bha:BH0633 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; SMART: AICARFT/IMPCHase bienzyme formylation region. (506 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (192 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: bha:BH0631 phosphoribosylaminoimidazole synthetase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. (344 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (469 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (739 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (226 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (80 aa) |
| | purC | KEGG: bcy:Bcer98_0270 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. (234 aa) |
| | ACQ71147.1 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: bha:BH0625 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (430 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (364 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (162 aa) |
| | guaA | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (513 aa) |
| | ACQ71005.1 | KEGG: bcy:Bcer98_1933 phosphoribulokinase/uridine kinase. (213 aa) |
| | ACQ71001.1 | RNA polymerase, sigma 28 subunit, Sig B/F/G subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (266 aa) |
| | ACQ70992.1 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: bsu:BSU11240 carbamoyl phosphate synthase large subunit. (1006 aa) |
| | carA | KEGG: bha:BH2896 carbamoyl phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (350 aa) |
| | ACQ70984.1 | PFAM: transcriptional coactivator/pterin dehydratase; KEGG: aba:Acid345_2331 pterin-4-alpha-carbinolamine dehydratase. (91 aa) |
| | ACQ70982.1 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (481 aa) |
| | ACQ70952.1 | Putative transcriptional regulator, PucR family; KEGG: bha:BH1072 hypothetical protein. (407 aa) |
| | ACQ70925.1 | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: bcy:Bcer98_3927 pyridoxal kinase. (274 aa) |
| | queC | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). (214 aa) |
| | ACQ70916.1 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: bcb:BCB4264_A1395 putative 6-pyruvoyl tetrahydrobiopterin synthase. (152 aa) |
| | queE | 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (236 aa) |
| | queF | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (162 aa) |
| | xpt | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (193 aa) |
| | ACQ70866.1 | Flavodoxin-like protein; KEGG: pmu:PM1499 protoporphyrinogen oxidase. (168 aa) |
| | ACQ70756.1 | PFAM: FAD dependent oxidoreductase; KEGG: bcb:BCB4264_A3172 oxidoreductase. (400 aa) |
| | ACQ70694.1 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: bha:BH0620 RNA polymerase ECF-type sigma factor. (173 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa) |
| | ACQ70676.1 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (450 aa) |
| | ACQ70655.1 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (379 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (487 aa) |
| | pdxS | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (296 aa) |
| | pdxT | SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (192 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (427 aa) |
| | ACQ70640.1 | PFAM: deoxynucleoside kinase; KEGG: bcy:Bcer98_0014 deoxynucleoside kinase. (223 aa) |
| | ACQ70639.1 | PFAM: deoxynucleoside kinase; KEGG: bce:BC0021 deoxyguanosine kinase. (211 aa) |
| | dnaX | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (558 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (212 aa) |
| | ACQ70630.1 | KEGG: bha:BH0044 DNA polymerase III subunit delta'. (330 aa) |
| | glmU | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (451 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (318 aa) |
| | ACQ70603.1 | KEGG: bcb:BCB4264_A0071 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (181 aa) |
| | coaX | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (254 aa) |
| | ACQ70598.1 | Anthranilate synthase; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; KEGG: bcr:BCAH187_A0080 para-aminobenzoate synthase, component I. (459 aa) |
| | ACQ70595.1 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (261 aa) |
| | ACQ70594.1 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (121 aa) |
| | ACQ70593.1 | KEGG: dar:Daro_3183 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. (165 aa) |
| | ACQ70576.1 | Transcriptional regulator, LuxR family; TIGRFAM: RNA polymerase sigma-H factor; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; regulatory protein LuxR; KEGG: bcu:BCAH820_0104 RNA polymerase sigma-30 factor. (213 aa) |
| | nusG | NusG antitermination factor; Participates in transcription elongation, termination and antitermination. (183 aa) |
| | rpoB | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1182 aa) |
| | rpoC | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1199 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (216 aa) |
| | rpoA | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (314 aa) |
| | ACQ70521.1 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-W factor; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: bha:BH0263 RNA polymerase sigma factor SigW; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa) |
| | dacA | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (286 aa) |
| | ACQ70475.1 | PFAM: protein of unknown function UPF0157; KEGG: bsu:BSU23670 hypothetical protein. (174 aa) |
| | ACQ70456.1 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. (224 aa) |
| | thiM | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (263 aa) |
| | ACQ70454.1 | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: msu:MS0677 phosphomethylpyrimidine kinase. (279 aa) |
| | thiE | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (213 aa) |
| | kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (424 aa) |
| | ACQ70421.1 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 4 domain protein; KEGG: aba:Acid345_0545 sigma-24, ECF subfamily. (186 aa) |
| | ACQ70418.1 | KEGG: spl:Spea_3171 ECF subfamily RNA polymerase sigma-24 factor; Belongs to the sigma-70 factor family. (101 aa) |
| | ACQ70415.1 | KEGG: bcz:BCZK1040 hypothetical protein. (66 aa) |
| | ACQ70409.1 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bsu:BSU31840 short chain dehydrogenase. (235 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (329 aa) |
| | trpC | PFAM: Indole-3-glycerol phosphate synthase; KEGG: bcz:BCZK1133 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (253 aa) |
| | trpF | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: bcr:BCAH187_A1397 N-(5'phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (184 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (394 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (255 aa) |
| | ACQ70372.1 | PFAM: Chlorite dismutase; KEGG: bha:BH3825 putative heme peroxidase. (258 aa) |
| | ACQ70371.1 | TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; KEGG: bcb:BCB4264_A5510 phosphate acetyltransferase. (329 aa) |
| | folE2 | Protein of unknown function DUF198; Converts GTP to 7,8-dihydroneopterin triphosphate. (303 aa) |
| | ACQ70336.1 | KEGG: mca:MCA0827 hypothetical protein. (375 aa) |
| | ACQ70296.1 | PFAM: GCN5-related N-acetyltransferase; KEGG: bsu:BSU06920 hypothetical protein. (154 aa) |
| | ACQ70285.1 | DNA-directed RNA polymerase delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. (159 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (531 aa) |
| | murA-2 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (418 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (445 aa) |
| | tdk | PFAM: thymidine kinase; KEGG: bha:BH3779 thymidine kinase. (203 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa) |
| | atpB | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (245 aa) |
| | atpE | ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (73 aa) |
| | atpF | ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (175 aa) |
| | atpH | ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (177 aa) |
| | atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (502 aa) |
| | atpG | ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (285 aa) |
| | atpD | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (472 aa) |
| | atpC | ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (136 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (433 aa) |
| | ACQ70117.1 | KEGG: maq:Maqu_2595 putative carbamoyl-phosphate-synthetase. (408 aa) |
| | ACQ70116.1 | PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: gur:Gura_1693 NAD-dependent epimerase/dehydratase. (370 aa) |
| | ACQ70110.1 | PFAM: WbqC-like family protein; KEGG: bch:Bcen2424_0233 hypothetical protein. (232 aa) |
| | ACQ70102.1 | Nucleotide sugar dehydrogenase; KEGG: bsu:BSU36230 hypothetical protein; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase. (413 aa) |
| | ACQ70073.1 | KEGG: bcb:BCB4264_A2871 hypothetical protein. (186 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (443 aa) |
| | ACQ69992.1 | Nucleotide sugar dehydrogenase; KEGG: bat:BAS5120 UDP-N-acetyl-D-mannosamine dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (429 aa) |
| | ACQ69903.1 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: pol:Bpro_3390 RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (180 aa) |
| | ACQ69796.1 | PFAM: sigma-54 DNA-binding domain protein; KEGG: dno:DNO_0532 RNA polymerase sigma-54 factor. (381 aa) |
| | ACQ69758.1 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: bsu:BSU21500 UV-damage repair protein. (431 aa) |
| | ACQ69730.1 | Putative RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: xca:xccb100_3976 conserved sigma factor-like protein. (423 aa) |
| | ACQ69689.1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (346 aa) |
| | ACQ69631.1 | TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase; KEGG: bcy:Bcer98_3343 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase. (363 aa) |
| | ACQ69623.1 | PFAM: RelA/SpoT domain protein; KEGG: bsu:BSU38480 hypothetical protein. (208 aa) |
| | nadK | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (269 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (403 aa) |
| | ACQ69605.1 | DNA polymerase III, alpha subunit; KEGG: bcy:Bcer98_3288 DNA polymerase III DnaE; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; nucleic acid binding OB-fold tRNA/helicase-type; SMART: phosphoesterase PHP domain protein. (1055 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (284 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (311 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (864 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (201 aa) |
| | ACQ69585.1 | PFAM: replication initiation and membrane attachment family protein; KEGG: bha:BH3145 chromosome replication initiation/membrane attachment protein. (450 aa) |
| | ACQ69558.1 | TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: bcy:Bcer98_3050 DNA polymerase III subunit delta. (339 aa) |
| | ACQ69557.1 | KEGG: bba:Bd0335 acetyltransferase. (145 aa) |
| | ACQ69551.1 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (384 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (603 aa) |
| | sigA | RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (364 aa) |
| | ACQ69491.1 | KEGG: bha:BH1414 hypothetical protein. (249 aa) |
| | ACQ69488.1 | TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: bca:BCE_4345 5-formyltetrahydrofolate cyclo-ligase family protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (184 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (162 aa) |
| | ACQ69463.1 | KEGG: bcb:BCB4264_A4942 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (175 aa) |
| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (145 aa) |
| | ACQ69456.1 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) |
| | nusB | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (128 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (278 aa) |
| | dxs | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (633 aa) |
| | ACQ69433.1 | KEGG: sbp:Sbal223_3821 hypothetical protein. (394 aa) |
| | ACQ69369.1 | TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: bat:BAS1388 ATP:cob(I)alamin adenosyltransferase, putative; Belongs to the Cob(I)alamin adenosyltransferase family. (183 aa) |
| | cinA | TIGRFAM: competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; KEGG: bha:BH2385 competence damage-inducible protein A; Belongs to the CinA family. (408 aa) |
| | ACQ69294.1 | PFAM: GCN5-related N-acetyltransferase; KEGG: sbp:Sbal223_1009 GCN5-related N-acetyltransferase. (141 aa) |
| | ACQ69291.1 | Guanosine polyphosphate pyrophosphohydrolase/synthetase-like protein; KEGG: sat:SYN_03611 GTP pyrophosphokinase / guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase. (282 aa) |
| | ACQ69270.1 | PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: bca:BCE_1836 cobalamin synthesis protein, putative. (399 aa) |
| | ACQ69237.1 | PFAM: RelA/SpoT domain protein; KEGG: ecz:ECS88_2201 hypothetical protein from phage origin. (352 aa) |
| | ACQ69116.1 | Conserved hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (231 aa) |
| | ACQ69107.1 | PFAM: GCN5-related N-acetyltransferase; KEGG: bsu:BSU06920 hypothetical protein. (162 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (251 aa) |
| | ACQ69078.1 | PFAM: FAD dependent oxidoreductase; KEGG: bcy:Bcer98_1848 FAD dependent oxidoreductase. (370 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa) |
| | ACQ69074.1 | Dihydrofolate reductase region; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (162 aa) |
| | ACQ69069.1 | PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: gbe:GbCGDNIH1_0170 GTP-dependent regulatory protein. (316 aa) |
| | ACQ69047.1 | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (152 aa) |
| | ACQ69035.1 | PFAM: GCN5-related N-acetyltransferase; KEGG: asu:Asuc_1059 GCN5-related N-acetyltransferase. (152 aa) |
| | ACQ69032.1 | KEGG: bcr:BCAH187_A2848 topology modulation protein. (184 aa) |
| | ACQ68944.1 | KEGG: bce:BC1864 DNA polymerase I; PFAM: DNA-directed DNA polymerase; SMART: DNA-directed DNA polymerase. (853 aa) |
| | udk | KEGG: bha:BH1275 uridine kinase; TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; SMART: AAA ATPase. (211 aa) |
| | ACQ71667.1 | PFAM: RelA/SpoT domain protein; KEGG: bar:GBAA1212 hypothetical protein. (214 aa) |
| | nadK-2 | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (265 aa) |
| | nadE | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (271 aa) |
| | ctaA | Cytochrome oxidase assembly; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 1 subfamily. (301 aa) |
| | ctaB | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. (307 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (164 aa) |
| | pyrR | Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (177 aa) |
| | pyrB | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; KEGG: bsu:BSU15490 aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (304 aa) |
| | pyrC | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (426 aa) |
| | carA-2 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: bcy:Bcer98_2536 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. (360 aa) |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: bha:BH2536 carbamoyl phosphate synthase large subunit. (1067 aa) |
| | pyrK | Oxidoreductase FAD/NAD(P)-binding domain protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (239 aa) |
| | pyrD | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. (308 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (234 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (208 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa) |
| | rpoZ | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (69 aa) |
| | ACQ71779.1 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (396 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (774 aa) |
| | ACQ71789.1 | TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase catalytic region; KEGG: bcy:Bcer98_2511 thiamine pyrophosphokinase. (195 aa) |
| | ACQ71831.1 | ATPase, FliI/YscN family; KEGG: bha:BH2455 flagellum-specific ATP synthase; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase. (439 aa) |
| | ACQ71854.1 | TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma-70 region 3 domain protein; KEGG: bsu:BSU16470 RNA polymerase sigma factor SigD. (256 aa) |
| | pyrH-2 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa) |
| | polC | DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1430 aa) |
| | nusA | NusA antitermination factor; Participates in both transcription termination and antitermination. (387 aa) |
| | ACQ71873.1 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; KEGG: bcb:BCB4264_A3907 riboflavin biosynthesis protein RibF; Belongs to the ribF family. (308 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa) |
