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| | ACQ70352.1 | PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: ilo:IL2539 threonine aldolase putative. (352 aa) |
| | ACQ69014.1 | TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; KEGG: bha:BH3206 histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (272 aa) |
| | ACQ69015.1 | PFAM: tRNA synthetase class II (G H P and S); KEGG: bcb:BCB4264_A1457 ATP phosphoribosyltransferase, regulatory subunit. (307 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (202 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (405 aa) |
| | ACQ69018.1 | PFAM: aminotransferase class I and II; KEGG: tcx:Tcr_1194 histidinol-phosphate aminotransferase. (338 aa) |
| | hisB | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: rpd:RPD_0415 imidazoleglycerol-phosphate dehydratase. (195 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (195 aa) |
| | hisA | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: sat:SYN_00761 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (237 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (255 aa) |
| | ACQ69023.1 | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family. (110 aa) |
| | hisE | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; MazG nucleotide pyrophosphohydrolase; KEGG: bsu:BSU34860 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein. (102 aa) |
| | ACQ69027.1 | PFAM: aminotransferase class I and II; KEGG: His8; Histidinol-phosphate aminotransferase, chloroplast precursor, probable; K00817 histidinol-phosphate aminotransferase. (337 aa) |
| | ACQ69048.1 | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: bca:BCE_1254 fumarylacetoacetate hydrolase family protein. (272 aa) |
| | ACQ69051.1 | TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: bcz:BCZK0314 amidohydrolase. (362 aa) |
| | fumC | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa) |
| | ACQ69074.1 | Dihydrofolate reductase region; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (162 aa) |
| | ACQ69082.1 | PFAM: aldo/keto reductase; KEGG: bsu:BSU33400 hypothetical protein. (270 aa) |
| | ACQ69084.1 | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: bsu:BSU18450 glutamate synthase (large subunit). (1479 aa) |
| | ACQ69085.1 | TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: bsu:BSU18440 glutamate synthase subunit beta. (483 aa) |
| | ACQ69136.1 | NADPH:quinone reductase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bca:BCE_0198 alcohol dehydrogenase, zinc-containing. (308 aa) |
| | ACQ69233.1 | PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: bha:BH3867 glutamine synthetase. (431 aa) |
| | ACQ69272.1 | PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: bcb:BCB4264_A2566 regucalcin family protein. (293 aa) |
| | argG | KEGG: bcz:BCZK4375 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (403 aa) |
| | argH | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: bsu:BSU29440 argininosuccinate lyase. (462 aa) |
| | ACQ69325.1 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (904 aa) |
| | ACQ69343.1 | KEGG: bcy:Bcer98_2381 glutamine synthetase, type I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp. (446 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (547 aa) |
| | ACQ69356.1 | Pyridoxal phosphate-dependent acyltransferase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (393 aa) |
| | ACQ69427.1 | PFAM: beta-lactamase domain protein; KEGG: bha:BH3178 metal-dependent hydrolase; Belongs to the UPF0173 family. (224 aa) |
| | ACQ69437.1 | PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: bcy:Bcer98_2854 branched-chain alpha-keto acid dehydrogenase subunit E2. (439 aa) |
| | ACQ69438.1 | PFAM: Transketolase central region; Transketolase domain protein; KEGG: bcb:BCB4264_A4271 3-methyl-2-oxobutanoate dehydrogenase, beta subunit. (325 aa) |
| | ACQ69439.1 | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); PFAM: dehydrogenase E1 component; KEGG: bha:BH2763 branched-chain alpha-keto acid dehydrogenase E1. (335 aa) |
| | ACQ69442.1 | PFAM: Glu/Leu/Phe/Val dehydrogenase dimerisation region; Glu/Leu/Phe/Val dehydrogenase; KEGG: bsu:BSU24080 leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (373 aa) |
| | ACQ69443.1 | PFAM: phosphate acetyl/butaryl transferase; KEGG: bcb:BCB4264_A4276 phosphate butyryltransferase. (298 aa) |
| | argR | Arginine repressor, ArgR; Regulates arginine biosynthesis genes. (149 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (278 aa) |
| | ACQ69456.1 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) |
| | ACQ69457.1 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (149 aa) |
| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (145 aa) |
| | gcvPB | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (491 aa) |
| | gcvPA | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (448 aa) |
| | gcvT | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (362 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (162 aa) |
| | ldh | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (318 aa) |
| | ispG | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (373 aa) |
| | ispH | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (317 aa) |
| | glyS | KEGG: bha:BH1371 glycyl-tRNA synthetase subunit beta; TIGRFAM: glycyl-tRNA synthetase, beta subunit. (684 aa) |
| | glyQ | KEGG: bha:BH1370 glycyl-tRNA synthetase subunit alpha; TIGRFAM: glycyl-tRNA synthetase, alpha subunit; PFAM: glycyl-tRNA synthetase alpha subunit. (300 aa) |
| | ACQ69539.1 | Cystathionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: bcb:BCB4264_A4491 Cys/Met metabolism PLP-dependent enzyme. (385 aa) |
| | ACQ69540.1 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bcb:BCB4264_A4492 O-acetylserine lyase. (312 aa) |
| | ACQ69553.1 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: bcy:Bcer98_2085 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding. (387 aa) |
| | serC | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (356 aa) |
| | pheT | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: bha:BH3110 phenylalanyl-tRNA synthetase subunit beta. (791 aa) |
| | pheS | KEGG: bsu:BSU28640 phenylalanyl-tRNA synthetase subunit alpha; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (340 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (647 aa) |
| | mdh | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (310 aa) |
| | ACQ69597.1 | KEGG: bsu:BSU29130 isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase. (423 aa) |
| | ACQ69600.1 | TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; PEP-utilising protein mobile region; Pyruvate kinase alpha/beta; KEGG: bcy:Bcer98_3282 pyruvate kinase; Belongs to the pyruvate kinase family. (580 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (322 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (311 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (284 aa) |
| | ACQ69619.1 | PFAM: Amidohydrolase 3; KEGG: bcz:BCZK4387 metal-dependent hydrolase. (523 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (415 aa) |
| | ACQ69631.1 | TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; chorismate mutase; PFAM: DAHP synthetase I/KDSA; Chorismate mutase; KEGG: bcy:Bcer98_3343 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase. (363 aa) |
| | ACQ69638.1 | PFAM: t-RNA-binding domain protein; KEGG: bha:BH3251 phenylalanyl-tRNA synthetase (beta subunit). (204 aa) |
| | ACQ69661.1 | PFAM: HI0933 family protein; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; KEGG: bha:BH3279 hypothetical protein. (421 aa) |
| | leuS | TIGRFAM: leucyl-tRNA synthetase; KEGG: bha:BH3281 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (801 aa) |
| | pgi | PFAM: phosphoglucose isomerase (PGI); KEGG: bcz:BCZK4630 glucose-6-phosphate isomerase; Belongs to the GPI family. (450 aa) |
| | ACQ69696.1 | PFAM: aldo/keto reductase; KEGG: bsu:BSU29050 hypothetical protein. (277 aa) |
| | ldh-2 | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (327 aa) |
| | ACQ69733.1 | Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (406 aa) |
| | gcvH | Glycine cleavage system H protein; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family. (127 aa) |
| | ACQ69745.1 | PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: bha:BH3486 butyryl-CoA dehydrogenase. (594 aa) |
| | ACQ69746.1 | KEGG: bcy:Bcer98_3596 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa) |
| | ACQ69747.1 | PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: bca:BCE_5144 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein. (803 aa) |
| | ACQ69752.1 | PFAM: Proline dehydrogenase; KEGG: bcb:BCB4264_A5153 proline dehydrogenase family protein. (305 aa) |
| | ACQ69788.1 | PFAM: aminoglycoside phosphotransferase; KEGG: bce:BC1129 trifolitoxin immunity protein. (265 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa) |
| | gpmI | Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (512 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa) |
| | pgk | PFAM: phosphoglycerate kinase; KEGG: bcy:Bcer98_3681 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (394 aa) |
| | ACQ69890.1 | PFAM: aldo/keto reductase; KEGG: aldehyde reductase; oxidoreductase. (297 aa) |
| | ACQ69909.1 | PFAM: regulatory protein TetR; KEGG: glo:Glov_3431 transcriptional regulator, TetR family. (204 aa) |
| | ACQ69974.1 | KEGG: vvy:VVA1509 tagatose-bisphosphate aldolase; TIGRFAM: class II aldolase, tagatose bisphosphate family; ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II. (289 aa) |
| | ACQ69992.1 | Nucleotide sugar dehydrogenase; KEGG: bat:BAS5120 UDP-N-acetyl-D-mannosamine dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (429 aa) |
| | ACQ70001.1 | PFAM: Heparinase II/III family protein; KEGG: bcz:BCZK4968 hypothetical protein. (697 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (443 aa) |
| | ACQ70073.1 | KEGG: bcb:BCB4264_A2871 hypothetical protein. (186 aa) |
| | ACQ70102.1 | Nucleotide sugar dehydrogenase; KEGG: bsu:BSU36230 hypothetical protein; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase. (413 aa) |
| | ACQ70117.1 | KEGG: maq:Maqu_2595 putative carbamoyl-phosphate-synthetase. (408 aa) |
| | ACQ70133.1 | TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein; KEGG: bha:BH2674 6-phosphogluconate dehydrogenase-like protein. (294 aa) |
| | ACQ70143.1 | PFAM: ferredoxin-dependent glutamate synthase; KEGG: bsu:BSU06590 hypothetical protein. (524 aa) |
| | ACQ70148.1 | TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein; KEGG: bha:BH2674 6-phosphogluconate dehydrogenase-like protein. (293 aa) |
| | nanE | N-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (231 aa) |
| | fabZ | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (140 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa) |
| | ACQ70258.1 | PFAM: ThiJ/PfpI domain protein; KEGG: mlo:mlr4512 hypothetical protein. (235 aa) |
| | ACQ70276.1 | Fructose-1,6-bisphosphate aldolase, class II; KEGG: bcy:Bcer98_3856 fructose-bisphosphate aldolase; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II. (284 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (531 aa) |
| | ACQ70302.1 | Coenzyme F390 synthetase-like protein; KEGG: aba:Acid345_3795 CapK protein, putative. (450 aa) |
| | ACQ70303.1 | Coenzyme F390 synthetase-like protein; KEGG: vch:VC0924 CapK protein, putative. (447 aa) |
| | ACQ70309.1 | TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: bsu:BSU37490 agmatinase; Belongs to the arginase family. (293 aa) |
| | murQ | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (294 aa) |
| | lipL | Biotin/lipoate A/B protein ligase; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes; Belongs to the octanoyltransferase LipL family. (280 aa) |
| | lipA | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (298 aa) |
| | lipM | Biotin/lipoate A/B protein ligase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation. (276 aa) |
| | ACQ70332.1 | PFAM: fatty acid desaturase; KEGG: bcb:BCB4264_A3000 fatty acid desaturase. (337 aa) |
| | ACQ70353.1 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: smd:Smed_2447 alcohol dehydrogenase zinc-binding domain protein. (326 aa) |
| | mtnA | Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (344 aa) |
| | mtnK | 5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (383 aa) |
| | ACQ70363.1 | PFAM: ribulose bisphosphate carboxylase large chain; KEGG: bcr:BCAH187_A4167 2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Belongs to the RuBisCO large chain family. (384 aa) |
| | mtnX | 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene). (216 aa) |
| | mtnB | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (205 aa) |
| | mtnD | Acireductone dioxygenase ARD; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (177 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (255 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (394 aa) |
| | trpF | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: bcr:BCAH187_A1397 N-(5'phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (184 aa) |
| | trpC | PFAM: Indole-3-glycerol phosphate synthase; KEGG: bcz:BCZK1133 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (253 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (329 aa) |
| | ACQ70400.1 | TIGRFAM: carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase; KEGG: bcy:Bcer98_0351 carbamate kinase; Belongs to the carbamate kinase family. (320 aa) |
| | ACQ70402.1 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (342 aa) |
| | arcA | KEGG: bcb:BCB4264_A0420 arginine deiminase; TIGRFAM: arginine deiminase; PFAM: amidinotransferase. (423 aa) |
| | ACQ70412.1 | TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pnu:Pnuc_1984 alcohol dehydrogenase. (330 aa) |
| | kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (424 aa) |
| | kynA | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (279 aa) |
| | kynB | Arylformamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. (207 aa) |
| | ACQ70486.1 | PFAM: GCN5-related N-acetyltransferase; KEGG: sus:Acid_5607 acetyltransferase. (264 aa) |
| | glmS | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (598 aa) |
| | ACQ70522.1 | Arginase; TIGRFAM: arginase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: bha:BH3948 arginase; Belongs to the arginase family. (300 aa) |
| | cysS | KEGG: bsu:BSU00940 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Belongs to the class-I aminoacyl-tRNA synthetase family. (465 aa) |
| | ACQ70581.1 | TIGRFAM: serine O-acetyltransferase; KEGG: bsu:BSU00930 serine acetyltransferase. (229 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (484 aa) |
| | ispF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (157 aa) |
| | lysS | TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: bsu:BSU00820 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (496 aa) |
| | ACQ70593.1 | KEGG: dar:Daro_3183 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. (165 aa) |
| | ACQ70594.1 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (121 aa) |
| | ACQ70595.1 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (261 aa) |
| | ACQ70596.1 | PFAM: aminotransferase class IV; KEGG: bcy:Bcer98_0066 4-amino-4-deoxychorismate lyase. (272 aa) |
| | ACQ70598.1 | Anthranilate synthase; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; KEGG: bcr:BCAH187_A0080 para-aminobenzoate synthase, component I. (459 aa) |
| | ACQ70599.1 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bcr:BCAH187_A0079 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. (317 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (293 aa) |
| | metG-2 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (653 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (427 aa) |
| | pdxT | SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (192 aa) |
| | ACQ70688.1 | KEGG: esa:ESA_01293 hypothetical protein. (81 aa) |
| | ACQ70731.1 | PFAM: aldo/keto reductase; KEGG: zmo:ZMO1344 2,5-diketo-D-gluconate reductase. (278 aa) |
| | ACQ70732.1 | KEGG: bcr:BCAH187_A2858 hypothetical protein. (320 aa) |
| | ACQ70750.1 | PFAM: GCN5-related N-acetyltransferase; KEGG: vha:VIBHAR_05434 acetyltransferase. (144 aa) |
| | ACQ70769.1 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: bha:BH3314 glycerate dehydrogenase. (320 aa) |
| | ACQ70785.1 | PFAM: ThiJ/PfpI domain protein; KEGG: bca:BCE_4593 ThiJ/PfpI family protein. (219 aa) |
| | ACQ70790.1 | Amidohydrolase; KEGG: bha:BH1613 N-acyl-L-amino acid amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein. (394 aa) |
| | glcB | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (727 aa) |
| | ACQ70822.1 | TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: bcr:BCAH187_A1287 isocitrate lyase. (425 aa) |
| | ACQ70828.1 | TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: sus:Acid_2928 assimilatory nitrate reductase (NADH) alpha subunit apoprotein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (748 aa) |
| | lutC | Protein of unknown function DUF162; Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. (230 aa) |
| | lutB | Iron-sulfur cluster binding protein; Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. (468 aa) |
| | lutA | Protein of unknown function DUF224 cysteine-rich region domain protein; Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. (245 aa) |
| | ACQ70893.1 | PFAM: GCN5-related N-acetyltransferase; KEGG: bcb:BCB4264_A2704 acetyltransferase. (143 aa) |
| | ACQ70933.1 | PFAM: aromatic amino acid hydroxylase; KEGG: bcy:Bcer98_3076 phenylalanine 4-monooxygenase. (519 aa) |
| | ACQ70951.1 | TIGRFAM: alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; KEGG: bsu:BSU31930 L-alanine dehydrogenase. (376 aa) |
| | argS | KEGG: bcr:BCAH187_A2318 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. (560 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (341 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (405 aa) |
| | ACQ70989.1 | TIGRFAM: acetylglutamate kinase; PFAM: aspartate/glutamate/uridylate kinase; KEGG: bha:BH2898 N-acetylglutamate 5-phosphotransferase. (259 aa) |
| | argD | TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: bca:BCE_4200 acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (381 aa) |
| | carA | KEGG: bha:BH2896 carbamoyl phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (350 aa) |
| | ACQ70992.1 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: bsu:BSU11240 carbamoyl phosphate synthase large subunit. (1006 aa) |
| | ACQ70993.1 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (308 aa) |
| | acpS | Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (122 aa) |
| | ACQ70996.1 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (358 aa) |
| | ACQ71013.1 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: smd:Smed_2447 alcohol dehydrogenase zinc-binding domain protein. (327 aa) |
| | ACQ71017.1 | PFAM: ThiJ/PfpI domain protein; KEGG: abo:ABO_2639 hypothetical protein. (220 aa) |
| | ACQ71067.1 | PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: vsa:VSAL_II0981 putative flavin containing amine oxidoreductase. (343 aa) |
| | ACQ71108.1 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bcr:BCAH187_A3512 oxidoreductase, zinc-binding dehydrogenase family. (320 aa) |
| | glmS-2 | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (598 aa) |
| | guaA | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (513 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (226 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (469 aa) |
| | glsA | PFAM: Glutaminase, core; KEGG: bha:BH2627 glutaminase; Belongs to the glutaminase family. (313 aa) |
| | nagB | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (254 aa) |
| | ACQ71180.1 | PFAM: Threonyl/alanyl tRNA synthetase SAD; KEGG: bcb:BCB4264_A3732 alanyl-tRNA synthetase family protein. (386 aa) |
| | ACQ71182.1 | KEGG: cha:CHAB381_0999 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (405 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (331 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (293 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (249 aa) |
| | dapH | Tetrahydrodipicolinate succinyltransferase domain protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (235 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (308 aa) |
| | ACQ71188.1 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (362 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (430 aa) |
| | rocD | Ornithine aminotransferase; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (400 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (263 aa) |
| | ACQ71221.1 | PFAM: cytochrome P450; KEGG: mes:Meso_4213 fatty acid alpha hydroxylase, cytochrome P450. (413 aa) |
| | ACQ71227.1 | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bcb:BCB4264_A1916 glyoxalase family protein. (137 aa) |
| | ACQ71238.1 | PFAM: beta-lactamase domain protein; KEGG: oca:OCAR_5178 beta lactamase. (266 aa) |
| | asnA | Aspartate/ammonia ligase; KEGG: bcy:Bcer98_1427 asparagine synthetase AsnA; TIGRFAM: aspartate/ammonia ligase; PFAM: aspartate--ammonia ligase. (326 aa) |
| | ACQ71249.1 | Nitrous oxidase accessory protein-like protein; KEGG: afw:Anae109_0246 carbohydrate-binding and sugar hydrolysis. (394 aa) |
| | ACQ71281.1 | PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: alcohol dehydrogenase GroES domain protein. (309 aa) |
| | ACQ71296.1 | TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: bsu:BSU30830 menaquinone-specific isochorismate synthase. (462 aa) |
| | ACQ71300.1 | PFAM: NUDIX hydrolase; KEGG: bcb:BCB4264_A3651 MutT/NUDIX family protein. (145 aa) |
| | ACQ71307.1 | PFAM: YfkB-like domain protein; Radical SAM domain protein; KEGG: bcu:BCAH820_0467 hypothetical protein. (368 aa) |
| | ACQ71316.1 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: bcu:BCAH820_0495 chlorohydrolase family protein. (384 aa) |
| | ACQ71358.1 | PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: bcb:BCB4264_A1634 rhodanese-like domain protein. (271 aa) |
| | ACQ71420.1 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: bha:BH0202 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (244 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (261 aa) |
| | odhA | 2-oxoglutarate dehydrogenase, E1 subunit; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). (951 aa) |
| | ACQ71458.1 | 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (424 aa) |
| | ACQ71463.1 | KEGG: bce:BC2695 outer membrane protein RomA. (364 aa) |
| | ACQ71472.1 | PFAM: aldo/keto reductase; KEGG: bcy:Bcer98_2796 2,5-didehydrogluconate reductase. (277 aa) |
| | ACQ71473.1 | KEGG: sus:Acid_7368 hypothetical protein. (302 aa) |
| | ACQ71528.1 | PFAM: Tetracycline transcriptional regulator YsiA domain protein; regulatory protein TetR; KEGG: bha:BH3102 TetR/AcrR family transcriptional regulator. (192 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (883 aa) |
| | nadA | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (359 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (147 aa) |
| | hisS | KEGG: bcr:BCAH187_A4536 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein. (427 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (590 aa) |
| | ACQ71623.1 | PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SM_b20422 putative oxidoreductase protein. (346 aa) |
| | ACQ71624.1 | PFAM: protein of unknown function DUF161; KEGG: bha:BH1258 hypothetical protein. (215 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (880 aa) |
| | mtnN | Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (233 aa) |
| | fabH | 3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (319 aa) |
| | ACQ71646.1 | 3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (410 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (333 aa) |
| | ACQ71671.1 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bha:BH2843 enoyl-(acyl carrier protein) reductase. (257 aa) |
| | ACQ71690.1 | Amidohydrolase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. (373 aa) |
| | pdhA | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (361 aa) |
| | ACQ71700.1 | PFAM: Transketolase central region; Transketolase domain protein; KEGG: bha:BH2654 pyruvate dehydrogenase E1 (lipoamide) beta subunit. (325 aa) |
| | ACQ71701.1 | PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: bha:BH2653 branched-chain alpha-keto acid dehydrogenase subunit E2. (429 aa) |
| | ACQ71719.1 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1144 aa) |
| | ACQ71742.1 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (280 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (908 aa) |
| | pyrB | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; KEGG: bsu:BSU15490 aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (304 aa) |
| | carA-2 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: bcy:Bcer98_2536 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. (360 aa) |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: bha:BH2536 carbamoyl phosphate synthase large subunit. (1067 aa) |
| | ACQ71779.1 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (396 aa) |
| | fapR | Fatty acid biosynthesis transcriptional regulator; Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism. (189 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (329 aa) |
| | ACQ71798.1 | TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: bsu:BSU15900 acyl-carrier-protein S-malonyltransferase. (306 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (79 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (385 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (569 aa) |
| | ACQ71894.1 | PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: bcb:BCB4264_A1546 glutamate dehydrogenase, NAD-specific; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (422 aa) |
| | ACQ71896.1 | PFAM: Asparaginase/glutaminase; KEGG: bcz:BCZK1377 L-asparaginase. (323 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (387 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (351 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (416 aa) |
| | ACQ71925.1 | PFAM: LmbE family protein; KEGG: bcb:BCB4264_A1590 hypothetical protein. (227 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (277 aa) |
| | panC | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (276 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (127 aa) |
| | asnS | TIGRFAM: asparaginyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); tRNA synthetase class II (G H P and S); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: bsu:BSU22360 asparaginyl-tRNA synthetase. (435 aa) |
