STRINGSTRING
lipA lipA lipL lipL ACQ70117.1 ACQ70117.1 metK metK ackA ackA accD accD accA accA ACQ69540.1 ACQ69540.1 ACQ69456.1 ACQ69456.1 folD folD dxs dxs ACQ69356.1 ACQ69356.1 ACQ69078.1 ACQ69078.1 ACQ70456.1 ACQ70456.1 thiM thiM ACQ70454.1 ACQ70454.1 mtnD mtnD thiE thiE ACQ70371.1 ACQ70371.1 mtnK mtnK ACQ70363.1 ACQ70363.1 mtnX mtnX mtnB mtnB gshAB gshAB mtnA mtnA lipM lipM ACQ71925.1 ACQ71925.1 ACQ71789.1 ACQ71789.1 mtnN mtnN ACQ71508.1 ACQ71508.1 ACQ71443.1 ACQ71443.1 asd asd ACQ70925.1 ACQ70925.1 ACQ70924.1 ACQ70924.1 ACQ70923.1 ACQ70923.1 ACQ70756.1 ACQ70756.1 ACQ70599.1 ACQ70599.1 ACQ70581.1 ACQ70581.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
lipALipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (298 aa)
lipLBiotin/lipoate A/B protein ligase; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes; Belongs to the octanoyltransferase LipL family. (280 aa)
ACQ70117.1KEGG: maq:Maqu_2595 putative carbamoyl-phosphate-synthetase. (408 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (402 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (403 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (284 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (311 aa)
ACQ69540.1PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bcb:BCB4264_A4492 O-acetylserine lyase. (312 aa)
ACQ69456.1acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
folDMethylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (278 aa)
dxsDeoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (633 aa)
ACQ69356.1Pyridoxal phosphate-dependent acyltransferase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (393 aa)
ACQ69078.1PFAM: FAD dependent oxidoreductase; KEGG: bcy:Bcer98_1848 FAD dependent oxidoreductase. (370 aa)
ACQ70456.1Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. (224 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (263 aa)
ACQ70454.1TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: msu:MS0677 phosphomethylpyrimidine kinase. (279 aa)
mtnDAcireductone dioxygenase ARD; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (177 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (213 aa)
ACQ70371.1TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; KEGG: bcb:BCB4264_A5510 phosphate acetyltransferase. (329 aa)
mtnK5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (383 aa)
ACQ70363.1PFAM: ribulose bisphosphate carboxylase large chain; KEGG: bcr:BCAH187_A4167 2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Belongs to the RuBisCO large chain family. (384 aa)
mtnX2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene). (216 aa)
mtnBMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (205 aa)
gshABGlutamate/cysteine ligase, /amino acid ligase; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily. (763 aa)
mtnATranslation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (344 aa)
lipMBiotin/lipoate A/B protein ligase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation. (276 aa)
ACQ71925.1PFAM: LmbE family protein; KEGG: bcb:BCB4264_A1590 hypothetical protein. (227 aa)
ACQ71789.1TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase catalytic region; KEGG: bcy:Bcer98_2511 thiamine pyrophosphokinase. (195 aa)
mtnNAdenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (233 aa)
ACQ71508.1TIGRFAM: sulfurtransferase DndC; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: bcz:BCZK0833 hypothetical protein. (551 aa)
ACQ71443.1PFAM: 3-demethylubiquinone-9 3-methyltransferase; Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bcr:BCAH187_A4779 hypothetical protein. (137 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (331 aa)
ACQ70925.1TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: bcy:Bcer98_3927 pyridoxal kinase. (274 aa)
ACQ70924.1KEGG: bha:BH3319 hypothetical protein. (123 aa)
ACQ70923.1PFAM: LmbE family protein; KEGG: bha:BH3320 hypothetical protein. (216 aa)
ACQ70756.1PFAM: FAD dependent oxidoreductase; KEGG: bcb:BCB4264_A3172 oxidoreductase. (400 aa)
ACQ70599.1TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bcr:BCAH187_A0079 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. (317 aa)
ACQ70581.1TIGRFAM: serine O-acetyltransferase; KEGG: bsu:BSU00930 serine acetyltransferase. (229 aa)
Your Current Organism:
Exiguobacterium sp. AT1b
NCBI taxonomy Id: 360911
Other names: E. sp. AT1b
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