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coq3 coq3 coq7 coq7 DLAC_08131 DLAC_08131 DLAC_08310 DLAC_08310 DLAC_08335 DLAC_08335 DLAC_07521 DLAC_07521 DLAC_07522 DLAC_07522 DLAC_07519 DLAC_07519 coq5 coq5 DLAC_06918 DLAC_06918 DLAC_11658 DLAC_11658 coq6 coq6 DLAC_11662 DLAC_11662 DLAC_05846 DLAC_05846 DLAC_06004 DLAC_06004 coq2 coq2 DLAC_05142 DLAC_05142 DLAC_04747 DLAC_04747 DLAC_03568 DLAC_03568 DLAC_03219 DLAC_03219 DLAC_03149 DLAC_03149 DLAC_02386 DLAC_02386 DLAC_00539 DLAC_00539
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
coq3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (295 aa)
coq75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (238 aa)
DLAC_08131Uncharacterized protein. (591 aa)
DLAC_08310Putative SAM dependent methyltransferase. (280 aa)
DLAC_08335NADPH:adrenodoxin oxidoreductase, mitochondrial. (506 aa)
DLAC_07521Uncharacterized protein. (601 aa)
DLAC_07522MADS-box domain-containing protein. (535 aa)
DLAC_07519Putative polyketide synthase. (2688 aa)
coq52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (305 aa)
DLAC_06918Uncharacterized protein. (603 aa)
DLAC_11658Methyltransf_11 domain-containing protein. (298 aa)
coq6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (465 aa)
DLAC_11662Polyketide_cyc domain-containing protein. (215 aa)
DLAC_05846Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (292 aa)
DLAC_06004Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (764 aa)
coq24-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (384 aa)
DLAC_05142Methyltranfer_dom domain-containing protein. (296 aa)
DLAC_04747ABC1 family protein kinase. (543 aa)
DLAC_03568Putative SAM dependent methyltransferase. (282 aa)
DLAC_03219Uncharacterized protein. (295 aa)
DLAC_03149Trans-prenyltransferase; Belongs to the FPP/GGPP synthase family. (458 aa)
DLAC_02386NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9. (362 aa)
DLAC_00539UbiA prenyltransferase family protein. (317 aa)
Your Current Organism:
Tieghemostelium lacteum
NCBI taxonomy Id: 361077
Other names: Dictyostelium lacteum, T. lacteum
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