(26 nodes) Pentose phosphate pathway network (Tieghemostelium lacteum)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Your Input:
	DLAC_07995	Uncharacterized protein. (248 aa)
	DLAC_11161	Ribose-5-phosphate isomerase. (238 aa)
	DLAC_09897	Senescence marker protein-30 family protein. (313 aa)
	DLAC_09877	Gluconokinase; Belongs to the gluconokinase GntK/GntV family. (182 aa)
	DLAC_10375	Phosphoglucomutase A; Belongs to the phosphohexose mutase family. (565 aa)
	DLAC_10096	Phosphoglucomutase; Belongs to the phosphohexose mutase family. (590 aa)
	DLAC_09662	RNA recognition motif-containing protein RRM. (590 aa)
	DLAC_09845	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (321 aa)
	DLAC_08561	Gluconate 2-dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (467 aa)
	DLAC_08702	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (319 aa)
	DLAC_08752	Phosphoribosyl pyrophosphate synthetase. (341 aa)
	DLAC_09321	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (231 aa)
	DLAC_07753	Phosphoribosyl pyrophosphate synthetase. (319 aa)
	DLAC_07801	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (493 aa)
	DLAC_00074	Uncharacterized protein. (424 aa)
	DLAC_00824	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (512 aa)
	DLAC_01742	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (360 aa)
	DLAC_11522	Str_synth domain-containing protein. (415 aa)
	DLAC_03431	D-fructose-1; Belongs to the FBPase class 1 family. (339 aa)
	DLAC_04203	Glucose-6-phosphate isomerase; Belongs to the GPI family. (556 aa)
	DLAC_04568	Uncharacterized protein. (832 aa)
	DLAC_04428	Phosphoribosyl pyrophosphate synthetase. (319 aa)
	DLAC_04320	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (250 aa)
	DLAC_06461	6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. (789 aa)
	DLAC_06896	Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (661 aa)
	DLAC_11707	Uncharacterized protein. (354 aa)

Your Current Organism:

Tieghemostelium lacteum

NCBI taxonomy Id: 361077
Other names: Dictyostelium lacteum, T. lacteum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLAC_00074	DLAC_00824	A0A152A8R6	A0A152A725	Uncharacterized protein.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.867
DLAC_00074	DLAC_01742	A0A152A8R6	A0A152A6H7	Uncharacterized protein.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.698
DLAC_00074	DLAC_03431	A0A152A8R6	A0A152A1Z9	Uncharacterized protein.	D-fructose-1; Belongs to the FBPase class 1 family.	0.837
DLAC_00074	DLAC_04203	A0A152A8R6	A0A151ZSI1	Uncharacterized protein.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.844
DLAC_00074	DLAC_04320	A0A152A8R6	A0A151ZJF6	Uncharacterized protein.	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.	0.692
DLAC_00074	DLAC_04568	A0A152A8R6	A0A151ZJU4	Uncharacterized protein.	Uncharacterized protein.	0.776
DLAC_00074	DLAC_06461	A0A152A8R6	A0A151ZEY1	Uncharacterized protein.	6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.	0.813
DLAC_00074	DLAC_06896	A0A152A8R6	A0A151ZDR2	Uncharacterized protein.	Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.	0.965
DLAC_00074	DLAC_07801	A0A152A8R6	A0A151ZAG2	Uncharacterized protein.	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.776
DLAC_00074	DLAC_07995	A0A152A8R6	A0A151ZAX7	Uncharacterized protein.	Uncharacterized protein.	0.600
DLAC_00074	DLAC_08561	A0A152A8R6	A0A151Z7Q8	Uncharacterized protein.	Gluconate 2-dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.714
DLAC_00074	DLAC_08702	A0A152A8R6	A0A151Z859	Uncharacterized protein.	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	0.500
DLAC_00074	DLAC_09321	A0A152A8R6	A0A151Z9S8	Uncharacterized protein.	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.	0.828
DLAC_00074	DLAC_09877	A0A152A8R6	A0A151Z5L1	Uncharacterized protein.	Gluconokinase; Belongs to the gluconokinase GntK/GntV family.	0.438
DLAC_00074	DLAC_10096	A0A152A8R6	A0A151Z647	Uncharacterized protein.	Phosphoglucomutase; Belongs to the phosphohexose mutase family.	0.477
DLAC_00074	DLAC_10375	A0A152A8R6	A0A151Z5Q4	Uncharacterized protein.	Phosphoglucomutase A; Belongs to the phosphohexose mutase family.	0.802
DLAC_00074	DLAC_11161	A0A152A8R6	A0A151Z3B4	Uncharacterized protein.	Ribose-5-phosphate isomerase.	0.815
DLAC_00824	DLAC_00074	A0A152A725	A0A152A8R6	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	Uncharacterized protein.	0.867
DLAC_00824	DLAC_01742	A0A152A725	A0A152A6H7	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.951
DLAC_00824	DLAC_03431	A0A152A725	A0A152A1Z9	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	D-fructose-1; Belongs to the FBPase class 1 family.	0.710