STRINGSTRING
ALE15432.1 ALE15432.1 aroC aroC ALE15610.1 ALE15610.1 ALE15883.1 ALE15883.1 ALE15972.1 ALE15972.1 ALE16005.1 ALE16005.1 ALE16192.1 ALE16192.1 aroB aroB aroK aroK leuA leuA ilvC ilvC ALE16344.1 ALE16344.1 ALE16345.1 ALE16345.1 ALE16347.1 ALE16347.1 ALE16518.1 ALE16518.1 ALE16521.1 ALE16521.1 trpD trpD trpC trpC ilvD ilvD aroA aroA trpF trpF trpB trpB trpA trpA leuB leuB ALE16882.1 ALE16882.1 leuC leuC leuD leuD ALE17099.1 ALE17099.1 ALE17100.1 ALE17100.1 ALE17101.1 ALE17101.1 ALE17192.1 ALE17192.1 thrB thrB hisC hisC ALE17527.1 ALE17527.1 ALE17618.1 ALE17618.1 aroE aroE ALE17931.1 ALE17931.1 ALE17957.1 ALE17957.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ALE15432.1Dihydroxy-acid dehydratase. (156 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (373 aa)
ALE15610.1Prephenate dehydratase. (297 aa)
ALE15883.1Threonine synthase. (466 aa)
ALE15972.1Chorismate mutase I. (113 aa)
ALE16005.1Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (354 aa)
ALE16192.1Threonine dehydratase, catabolic. (318 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (369 aa)
aroKShikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (189 aa)
leuAHypothetical protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (557 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
ALE16344.1Acetolactate synthase small subunit. (171 aa)
ALE16345.1Acetolactate synthase large subunit. (581 aa)
ALE16347.1Phosphoserine phosphatase. (282 aa)
ALE16518.1Anthranilate synthase, aminase component. (403 aa)
ALE16521.1Anthranilate synthase, amidotransferase component. (194 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (330 aa)
trpCIndole-3-glycerol phosphate synthase; Belongs to the TrpC family. (261 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (619 aa)
aroA5-Enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (437 aa)
trpFPhosphoribosylanthranilate isomerase; Belongs to the TrpF family. (210 aa)
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (404 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (259 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (356 aa)
ALE16882.1Branched-chain amino acid aminotransferase. (359 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (477 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (204 aa)
ALE17099.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa)
ALE17100.1Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (385 aa)
ALE17101.1Glycosyltransferase. (396 aa)
ALE17192.1Threonine dehydratase. (417 aa)
thrBHomoserine kinase; Belongs to the pseudomonas-type ThrB family. (326 aa)
hisCHomoserine O-acetyltransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (394 aa)
ALE17527.1Cyclohexadienyl dehydrogenase. (305 aa)
ALE17618.1Para-aminobenzoate synthase, aminase component / Aminodeoxychorismate lyase. (608 aa)
aroEShikimate 5-dehydrogenase I alpha; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (285 aa)
ALE17931.1Low-specificity L-threonine aldolase. (335 aa)
ALE17957.1Homoserine dehydrogenase. (436 aa)
Your Current Organism:
Altererythrobacter epoxidivorans
NCBI taxonomy Id: 361183
Other names: A. epoxidivorans, Altererythrobacter epoxidivorans Kwon et al. 2007, JCM 13815, KCCM 42314, strain JCS350
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