STRINGSTRING
ALE17723.1 ALE17723.1 ALE18085.1 ALE18085.1 ALE18058.1 ALE18058.1 prs prs gpmA gpmA ALE17920.1 ALE17920.1 ALE17890.1 ALE17890.1 ALE17814.1 ALE17814.1 coaE coaE ALE17795.1 ALE17795.1 ALE17792.1 ALE17792.1 ALE17758.1 ALE17758.1 ALE17745.1 ALE17745.1 ALE17647.1 ALE17647.1 ALE17637.1 ALE17637.1 ALE17635.1 ALE17635.1 ALE17616.1 ALE17616.1 ALE17594.1 ALE17594.1 argB argB ALE17502.1 ALE17502.1 ALE17500.1 ALE17500.1 ALE17491.1 ALE17491.1 ALE17454.1 ALE17454.1 ALE17443.1 ALE17443.1 ALE17440.1 ALE17440.1 ALE17396.1 ALE17396.1 ALE17391.1 ALE17391.1 ALE17358.1 ALE17358.1 ALE17353.1 ALE17353.1 ALE17333.1 ALE17333.1 ALE17329.1 ALE17329.1 glk glk proB-2 proB-2 ALE17277.1 ALE17277.1 ALE17224.1 ALE17224.1 thrB thrB proB proB ALE17125.1 ALE17125.1 ALE17071.1 ALE17071.1 ALE17069.1 ALE17069.1 ALE17068.1 ALE17068.1 ALE17011.1 ALE17011.1 ppk ppk ALE16968.1 ALE16968.1 adk adk ALE16799.1 ALE16799.1 ALE16760.1 ALE16760.1 cmk cmk ispE ispE nnrE nnrE ALE16557.1 ALE16557.1 coaX coaX ALE16534.1 ALE16534.1 ALE16531.1 ALE16531.1 tpiA tpiA pdhA pdhA ALE16504.1 ALE16504.1 ALE16486.1 ALE16486.1 ALE16484.1 ALE16484.1 tmk tmk ALE16469.1 ALE16469.1 ALE16467.1 ALE16467.1 ALE16434.1 ALE16434.1 ALE16412.1 ALE16412.1 eno eno ALE16327.1 ALE16327.1 ALE16303.1 ALE16303.1 ALE16285.1 ALE16285.1 pgk pgk ALE16282.1 ALE16282.1 ALE16281.1 ALE16281.1 ALE16274.1 ALE16274.1 nadK nadK ALE16251.1 ALE16251.1 ALE16249.1 ALE16249.1 aroK aroK pgi pgi cysN cysN ALE16181.1 ALE16181.1 ndk ndk tdk tdk pyrH pyrH ALE15970.1 ALE15970.1 ALE15949.1 ALE15949.1 ALE15844.1 ALE15844.1 ALE15822.1 ALE15822.1 ALE15817.1 ALE15817.1 ALE15801.1 ALE15801.1 ALE15789.1 ALE15789.1 ALE15748.1 ALE15748.1 ALE15741.1 ALE15741.1 gmk gmk ALE15617.1 ALE15617.1 ALE15615.1 ALE15615.1 ALE15496.1 ALE15496.1 ALE15482.1 ALE15482.1 ALE15480.1 ALE15480.1 ALE15428.1 ALE15428.1 ALE15377.1 ALE15377.1 ALE15327.1 ALE15327.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALE17723.1DAG-kinase catalytic domain. (341 aa)
ALE18085.1Pyruvate kinase; Belongs to the pyruvate kinase family. (489 aa)
ALE18058.1Signal transduction histidine kinase. (425 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (311 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (232 aa)
ALE17920.1Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. (313 aa)
ALE17890.1Tyrosine-protein kinase EpsD. (720 aa)
ALE17814.1ATP /GTP-binding protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (282 aa)
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (198 aa)
ALE17795.1Two-component signal transduction histidine kinase. (400 aa)
ALE17792.1Hypothetical protein. (284 aa)
ALE17758.1Fructokinase. (331 aa)
ALE17745.1Autolysin sensor kinase. (405 aa)
ALE17647.13-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
ALE17637.1Transcriptional regulator. (261 aa)
ALE17635.1Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (410 aa)
ALE17616.1Sensor histidine kinase. (483 aa)
ALE17594.1GGDEF domain. (480 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (299 aa)
ALE17502.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (167 aa)
ALE17500.1Chemotaxis protein methyltransferase CheR. (1129 aa)
ALE17491.1Sensor histidine kinase /response regulator. (908 aa)
ALE17454.13-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (420 aa)
ALE17443.1HipA protein. (423 aa)
ALE17440.1DNA helicase, putative. (1840 aa)
ALE17396.1Diguanylate cyclase /phosphodiesterase (GGDEF & EAL domains) with PAS /PAC sensor(s). (769 aa)
ALE17391.1Two-component hybrid sensor and regulator. (710 aa)
ALE17358.1Hypothetical protein. (490 aa)
ALE17353.1Signal transduction histidine kinase CheA. (787 aa)
ALE17333.1Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (489 aa)
ALE17329.1Phosphocarrier protein kinase /phosphorylase, nitrogen regulation associated; Belongs to the PEP-utilizing enzyme family. (739 aa)
glkGlucokinase; Belongs to the bacterial glucokinase family. (330 aa)
proB-2Glutamate 5-kinase / RNA-binding C-terminal domain PUA; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (379 aa)
ALE17277.1Hypothetical protein. (199 aa)
ALE17224.13-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
thrBHomoserine kinase; Belongs to the pseudomonas-type ThrB family. (326 aa)
proBGlutamate 5-kinase / RNA-binding C-terminal domain PUA; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (371 aa)
ALE17125.1Hedgehog-like protein. (222 aa)
ALE17071.1PTS system permease (IIAMan), nitrogen regulatory IIA protein. (141 aa)
ALE17069.1HPr kinase / phosphorylase. (143 aa)
ALE17068.1Sensor histidine kinase ChvG. (518 aa)
ALE17011.1Hypothetical protein. (293 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (718 aa)
ALE16968.1Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit. (737 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa)
ALE16799.12-oxoglutarate dehydrogenase E1 component. (948 aa)
ALE16760.1Sensory box histidine kinase /response regulator. (820 aa)
cmkCytidylate kinase. (208 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (270 aa)
nnrENAD(P)HX epimerase / NAD(P)HX dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] (463 aa)
ALE16557.13-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
coaXPantothenate kinase type III, CoaX-like; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (257 aa)
ALE16534.1Hypothetical protein. (91 aa)
ALE16531.1Two-component signal transduction histidine kinase. (459 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (253 aa)
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (361 aa)
ALE16504.1Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (466 aa)
ALE16486.1Nitrogen regulation protein NtrB. (357 aa)
ALE16484.1Nitrogen regulation protein NtrY. (737 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (214 aa)
ALE16469.1Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex. (470 aa)
ALE16467.1Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (432 aa)
ALE16434.1Hypothetical protein. (295 aa)
ALE16412.1Pyruvate,phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (886 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
ALE16327.1Phosphate regulon sensor protein PhoR (SphS). (399 aa)
ALE16303.1Sensory transduction histidine kinase. (705 aa)
ALE16285.1Fructose-bisphosphate aldolase class I. (294 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa)
ALE16282.1NAD-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
ALE16281.1Transketolase; Belongs to the transketolase family. (666 aa)
ALE16274.1Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit. (435 aa)
nadKNAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (277 aa)
ALE16251.1Putative phosphotransferase related to Ser /Thr protein kinase. (334 aa)
ALE16249.1Sensor. (779 aa)
aroKShikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (189 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (513 aa)
cysNSulfate adenylyltransferase subunit 1 / Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (639 aa)
ALE16181.1Hypothetical protein. (73 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
tdkThymidine kinase. (192 aa)
pyrHUridine monophosphate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa)
ALE15970.1Signal transduction histidine kinase. (495 aa)
ALE15949.1Hypothetical protein. (600 aa)
ALE15844.1Thiamine-monophosphate kinase. (248 aa)
ALE15822.1Sensor histidine kinase. (1119 aa)
ALE15817.1Hypothetical protein. (116 aa)
ALE15801.12-dehydro-3-deoxygluconate kinase. (341 aa)
ALE15789.13-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
ALE15748.1Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical). (127 aa)
ALE15741.1Hypothetical protein. (188 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (211 aa)
ALE15617.1Hydroxymethylpyrimidine phosphate kinase ThiD. (269 aa)
ALE15615.1Hypothetical protein. (356 aa)
ALE15496.1Tyrosine-protein kinase EpsD. (736 aa)
ALE15482.1Hypothetical protein. (89 aa)
ALE15480.1Serine kinase of the HPr protein, regulates carbohydrate metabolism. (283 aa)
ALE15428.1Two-component sensor histidine kinase. (427 aa)
ALE15377.1HIPA protein. (432 aa)
ALE15327.1Aspartokinase; Belongs to the aspartokinase family. (438 aa)
Your Current Organism:
Altererythrobacter epoxidivorans
NCBI taxonomy Id: 361183
Other names: A. epoxidivorans, Altererythrobacter epoxidivorans Kwon et al. 2007, JCM 13815, KCCM 42314, strain JCS350
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