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ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa) | ||||
LSL_1141 | Copper homeostasis protein cutC. (187 aa) | ||||
hpf | Ribosome-associated factor Y; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (184 aa) | ||||
LSL_1191 | Phage transcriptional regulator, Cro/CI family; COG0640 [K] Predicted transcriptional regulators. (165 aa) | ||||
LSL_1193 | Phage immunity repressor. (126 aa) | ||||
LSL_1201 | Hypothetical protein, phage associated. (256 aa) | ||||
LSL_1202 | DNA primase; COG0433 [R] Predicted ATPase. (516 aa) | ||||
LSL_1210 | COG0474 [P] Cation transport ATPase. (800 aa) | ||||
LSL_1225 | Conserved hypothetical protein. (79 aa) | ||||
recR | Recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (199 aa) | ||||
LSL_1227 | Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (104 aa) | ||||
tadA | Cytosine/adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (166 aa) | ||||
rplL | LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (122 aa) | ||||
rplJ | LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (167 aa) | ||||
rplA | LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (230 aa) | ||||
rplK | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (141 aa) | ||||
rpmG-2 | COG0267 [J] Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (50 aa) | ||||
mrnC | Conserved hypothetical protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. (135 aa) | ||||
wecD-7 | Acetyltransferase. (92 aa) | ||||
LSL_1273 | COG2423 [E] Predicted ornithine cyclodeaminase, mu-crystallin homolog. (328 aa) | ||||
srmB-4 | COG0513 [LKJ] Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. (426 aa) | ||||
LSL_1296 | Conserved hypothetical protein. (347 aa) | ||||
mgtE | Mg2+ transporter; Acts as a magnesium transporter. (455 aa) | ||||
topB | DNA topoisomerase III; COG0550 [L] Topoisomerase IA. (691 aa) | ||||
ackA-2 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa) | ||||
wecD-11 | Acetyltransferase; COG2388 [R] Predicted acetyltransferase. (207 aa) | ||||
LSL_1352 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (330 aa) | ||||
LSL_1356 | S1-type RNA-binding domain; COG1098 [J] Predicted RNA binding protein (contains ribosomal protein S1 domain). (154 aa) | ||||
LSL_1363 | Conserved hypothetical protein; COG1787 [V] Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes. (757 aa) | ||||
tyrS | Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (416 aa) | ||||
sbcD | Exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (371 aa) | ||||
LSL_1387 | Conserved hypothetical protein; COG2020 [O] Putative protein-S-isoprenylcysteine methyltransferase. (187 aa) | ||||
rnmV2 | Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step; Belongs to the ribonuclease M5 family. (189 aa) | ||||
rpsI | COG0103 [J] Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (130 aa) | ||||
rplM | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (147 aa) | ||||
truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (256 aa) | ||||
rplQ | COG0203 [J] Ribosomal protein L17. (127 aa) | ||||
rpsK | SSU ribosomal protein S11P; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (128 aa) | ||||
rpsM | SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (121 aa) | ||||
rpmJ | COG0257 [J] Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (37 aa) | ||||
adk | Adenylate kinase / Nucleoside-diphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (219 aa) | ||||
rplO | LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (144 aa) | ||||
rpmD | COG1841 [J] Ribosomal protein L30/L7E. (60 aa) | ||||
rpsE | SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (166 aa) | ||||
rplR | LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (118 aa) | ||||
rplF | LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa) | ||||
rpsH | SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa) | ||||
rpsN | SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa) | ||||
rplE | LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (180 aa) | ||||
rplX | LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (101 aa) | ||||
rplN | LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa) | ||||
rpsQ | SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (88 aa) | ||||
rpmC | COG0255 [J] Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (64 aa) | ||||
rplP | LSU ribosomal protein L16P; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (144 aa) | ||||
rpsC | SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (218 aa) | ||||
rplV | LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (115 aa) | ||||
rpsS | SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (93 aa) | ||||
rplB | LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (277 aa) | ||||
rplW | LSU ribosomal protein L23P; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (94 aa) | ||||
rplD | LSU ribosomal protein L1E; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (207 aa) | ||||
rplC | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (207 aa) | ||||
rpsJ | SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) | ||||
LSL_1441 | Hypothetical protein. (130 aa) | ||||
LSL_1460 | Conserved hypothetical protein; COG0845 [M] Membrane-fusion protein. (357 aa) | ||||
LSL_1467 | COG0624 [E] Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (378 aa) | ||||
trxA-3 | Thioredoxin; COG0526 [OC] Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. (107 aa) | ||||
treB | PTS system, trehalose-specific IIBC component; COG1263 [G] Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. (640 aa) | ||||
LSL_1529 | Hypothetical membrane spanning protein. (186 aa) | ||||
rfbB | COG1088 [M] dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (343 aa) | ||||
ychF | GTP-binding protein, probable translation factor; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (366 aa) | ||||
parB | Chromosome partitioning protein, DNA-binding protein; COG0640 [K] Predicted transcriptional regulators; Belongs to the ParB family. (291 aa) | ||||
LSL_1602 | COG0474 [P] Cation transport ATPase. (881 aa) | ||||
LSL_1642 | COG1428 [F] Deoxynucleoside kinases. (245 aa) | ||||
LSL_1649 | Transcriptional regulator, Cro/CI family; COG0583 [K] Transcriptional regulator. (267 aa) | ||||
LSL_1657 | Hypothetical protein, phage associated. (256 aa) | ||||
LSL_1658 | DNA primase; COG0433 [R] Predicted ATPase. (464 aa) | ||||
LSL_1721 | COG1607 [I] Acyl-CoA hydrolase. (169 aa) | ||||
rpmH | COG0230 [J] Ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (44 aa) | ||||
dnaB-2 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (463 aa) | ||||
recF | DNA replication and repair protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (379 aa) | ||||
gyrB | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (652 aa) | ||||
rpsF | SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA. (96 aa) | ||||
rpsR | SSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (78 aa) | ||||
gldA | COG0371 [C] Glycerol dehydrogenase and related enzymes. (363 aa) | ||||
phnP | COG1235 [R] Metal-dependent hydrolases of the beta-lactamase superfamily I. (267 aa) | ||||
LSL_0046 | Short chain dehydrogenase; COG1028 [IQR] Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (282 aa) | ||||
scrA | PTS system, sucrose-specific IIABC component; COG1263 [G] Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific. (644 aa) | ||||
serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (363 aa) | ||||
LSL_0128 | COG1791 [S] Uncharacterized conserved protein, contains double-stranded beta-helix domain. (136 aa) | ||||
LSL_0133 | COG0624 [E] Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (382 aa) | ||||
LSL_0136 | COG1250 [I] 3-hydroxyacyl-CoA dehydrogenase. (293 aa) | ||||
acoB | COG0022 [C] Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (325 aa) | ||||
LSL_0179 | COG4690 [E] Dipeptidase. (472 aa) | ||||
rpsL | SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. (137 aa) | ||||
rpsG | SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) | ||||
sir2 | SIR2 family protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. (243 aa) | ||||
czcD | Cobalt-zinc-cadmium resistance protein; COG0053 [P] Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (341 aa) | ||||
LSL_0224 | COG1257 [I] Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (421 aa) | ||||
rnmV1 | Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step; Belongs to the ribonuclease M5 family. (185 aa) | ||||
ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (289 aa) | ||||
LSL_0257 | Replisome organizer, phage associated. (327 aa) | ||||
mcrA | COG1403 [V] Restriction endonuclease. (176 aa) | ||||
LSL_0324 | Metallo-beta-lactamase family protein; COG2220 [R] Predicted Zn-dependent hydrolases of the beta-lactamase fold; Belongs to the UPF0173 family. (219 aa) | ||||
LSL_0338 | Hydrolase; COG1078 [R] HD superfamily phosphohydrolases. (451 aa) | ||||
rpmE | COG0254 [J] Ribosomal protein L31. (82 aa) | ||||
srmB | Superfamily II DNA and RNA helicase; COG1199 [KL] Rad3-related DNA helicases. (788 aa) | ||||
srmB-2 | ATP-dependent RNA helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. (492 aa) | ||||
LSL_0409 | COG0700 [S] Uncharacterized membrane protein. (230 aa) | ||||
LSL_0410 | COG0700 [S] Uncharacterized membrane protein. (229 aa) | ||||
LSL_0440 | Polyribonucleotide nucleotidyltransferase; COG1098 [J] Predicted RNA binding protein (contains ribosomal protein S1 domain). (136 aa) | ||||
fabB | 3-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa) | ||||
LSL_0469 | N-acetyldiaminopimelate deacetylase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. (381 aa) | ||||
trxA | Thioredoxin; COG0526 [OC] Thiol-disulfide isomerase and thioredoxins. (105 aa) | ||||
dnaB | COG3611 [L] Replication initiation/membrane attachment protein. (448 aa) | ||||
dnaI | COG1484 [L] DNA replication protein. (309 aa) | ||||
rpmI | COG0291 [J] Ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (66 aa) | ||||
rplT | LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (120 aa) | ||||
LSL_0500 | GTP-binding protein; COG1160 [R] Predicted GTPases. (373 aa) | ||||
nadD | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (210 aa) | ||||
rpmF | COG0333 [J] Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (58 aa) | ||||
rpsB | COG0052 [J] Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (265 aa) | ||||
LSL_0514 | COG1428 [F] Deoxynucleoside kinases. (240 aa) | ||||
LSL_0526 | COG3425 [I] 3-hydroxy-3-methylglutaryl CoA synthase. (387 aa) | ||||
ispA | Geranyltranstransferase; COG0142 [H] Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (297 aa) | ||||
recN | DNA repair protein; May be involved in recombinational repair of damaged DNA. (555 aa) | ||||
rpmG | COG0267 [J] Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (49 aa) | ||||
LSL_0550 | Integral membrane protein, Rhomboid family; COG0705 [R] Uncharacterized membrane protein (homolog of Drosophila rhomboid). (220 aa) | ||||
ada | COG0350 [L] Methylated DNA-protein cysteine methyltransferase. (153 aa) | ||||
rPL | COG1358 [J] Ribosomal protein HS6-type (S12/L30/L7a). (101 aa) | ||||
ribF | Riboflavin kinase / FMN adenylyltransferase; COG0196 [H] FAD synthase; Belongs to the ribF family. (318 aa) | ||||
murE-2 | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; COG0769 [M] UDP-N-acetylmuramyl tripeptide synthase. (449 aa) | ||||
LSL_0610 | Hypothetical protein. (284 aa) | ||||
priA | Primosomal protein n-prim; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (792 aa) | ||||
rpmB | COG0227 [J] Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (61 aa) | ||||
smc | Chromosome partition protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1178 aa) | ||||
rpsP | COG0228 [J] Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (91 aa) | ||||
rplS | LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (118 aa) | ||||
rpsT | SSU ribosomal protein S20P; Binds directly to 16S ribosomal RNA. (84 aa) | ||||
rpsO | SSU ribosomal protein S15P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa) | ||||
purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (483 aa) | ||||
purD | COG0151 [F] Phosphoribosylamine-glycine ligase; Belongs to the GARS family. (418 aa) | ||||
comEB | ComE operon protein 2; COG2131 [F] Deoxycytidylate deaminase. (158 aa) | ||||
fni | Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (348 aa) | ||||
LSL_0690 | DNA replication protein dnaD; COG3935 [L] Putative primosome component and related proteins. (235 aa) | ||||
nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (213 aa) | ||||
rpsU | COG0828 [J] Ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. (61 aa) | ||||
LSL_0717 | GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (285 aa) | ||||
topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (703 aa) | ||||
LSL_0733 | Transposase ISLasa9a, IS200-IS605 family; COG0675 [L] Transposase and inactivated derivatives. (425 aa) | ||||
LSL_0742 | Phage transcriptional regulator, Cro/CI family; COG0640 [K] Predicted transcriptional regulators. (131 aa) | ||||
LSL_0752 | Phage helicase; COG0553 [KL] Superfamily II DNA/RNA helicases, SNF2 family. (407 aa) | ||||
LSL_0758 | Phage DNA polymerase. (565 aa) | ||||
LSL_0759 | Phage primase. (343 aa) | ||||
LSL_0760 | Phage DNA primase; COG0433 [R] Predicted ATPase. (289 aa) | ||||
mcrA-2 | COG1403 [V] Restriction endonuclease. (108 aa) | ||||
udk | COG0572 [F] Uridine kinase. (213 aa) | ||||
dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (148 aa) | ||||
LSL_0840 | Ribonuclease HI / Cell wall enzyme EBSB. (128 aa) | ||||
fhs | Formate--tetrahydrofolate ligase; COG2759 [F] Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. (552 aa) | ||||
nifS | COG1104 [E] Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. (380 aa) | ||||
gyrB-2 | Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily. (673 aa) | ||||
LSL_0885 | DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (91 aa) | ||||
rpsA | COG0539 [J] Ribosomal protein S1. (399 aa) | ||||
recO | DNA repair protein; Involved in DNA repair and RecF pathway recombination. (260 aa) | ||||
dgkA | COG0818 [M] Diacylglycerol kinase. (138 aa) | ||||
ybeY | Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (159 aa) | ||||
recQ | COG0514 [L] Superfamily II DNA helicase. (481 aa) | ||||
LSL_0905 | COG0720 [H] 6-pyruvoyl-tetrahydropterin synthase. (122 aa) | ||||
dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (617 aa) | ||||
rpmA | COG0211 [J] Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (93 aa) | ||||
rplU | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (102 aa) | ||||
gAlE | UDP-glucose 4-epimerase; COG0451 [MG] Nucleoside-diphosphate-sugar epimerases. (319 aa) | ||||
LSL_0967 | Hypothetical protein. (269 aa) | ||||
qor | COG0604 [CR] NADPH:quinone reductase and related Zn-dependent oxidoreductases. (334 aa) | ||||
LSL_0980 | UDP-glucuronate 4-epimerase; COG0451 [MG] Nucleoside-diphosphate-sugar epimerases. (359 aa) | ||||
lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (430 aa) | ||||
LSL_1006 | COG4690 [E] Dipeptidase. (474 aa) | ||||
LSL_1018 | Cellulose synthase catalytic subunit; UDP-forming. (690 aa) | ||||
draG | COG1397 [O] ADP-ribosylglycohydrolase. (328 aa) | ||||
LSL_1044 | RNA binding protein; COG2302 [S] Uncharacterized conserved protein, contains S4-like domain. (262 aa) | ||||
radC | COG2003 [L] DNA repair proteins; Belongs to the UPF0758 family. (225 aa) | ||||
nifS-2 | COG1104 [E] Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. (382 aa) | ||||
ezrA | Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. (570 aa) | ||||
rpsD | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (201 aa) | ||||
LSL_1079 | ATPase, AAA family; COG2256 [L] ATPase related to the helicase subunit of the Holliday junction resolvase. (423 aa) | ||||
LSL_1092 | COG0300 [R] Short-chain dehydrogenases of various substrate specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (269 aa) | ||||
rnz | Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (317 aa) | ||||
trxA-2 | Thioredoxin; COG0526 [OC] Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. (103 aa) | ||||
LSL_1109 | Endonuclease involved in recombination; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (143 aa) | ||||
srmB-3 | ATP-dependent RNA helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. (440 aa) | ||||
LSL_1113 | Phosphoesterase, DHH family protein; COG0618 [R] Exopolyphosphatase-related proteins. (324 aa) |