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dut dut upp upp pyrD pyrD pyrC1 pyrC1 dcd dcd pyrE1 pyrE1 pyrB pyrB pyrC2 pyrC2 HQ_1998A HQ_1998A hts hts carA carA pyrF pyrF pyrE2 pyrE2 carB carB surE1 surE1 surE2 surE2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dutdUTP diphosphatase. (157 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (226 aa)
pyrDDihydroorotate dehydrogenase (quinone). (357 aa)
pyrC1Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (434 aa)
dcddCTP deaminase; Catalyzes the deamination of dCTP to dUTP. (206 aa)
pyrE1Homolog to orotate phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (221 aa)
pyrBAspartate carbamoyltransferase catalytic subunit. (304 aa)
pyrC2Metal-dependent hydrolase (homolog to dihydroorotase / allantoinase). (474 aa)
HQ_1998AHomolog to dUTP diphosphatase. (138 aa)
htsThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (336 aa)
carACarbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit; Belongs to the CarA family. (366 aa)
pyrFOrotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (275 aa)
pyrE2Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (182 aa)
carBCarbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit; Belongs to the CarB family. (1088 aa)
surE15'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (265 aa)
surE25'-nucleotidase SurE. (283 aa)
Your Current Organism:
Haloquadratum walsbyi DSM 16790
NCBI taxonomy Id: 362976
Other names: H. walsbyi DSM 16790, Haloquadratum walsbyi str. DSM 16790, Haloquadratum walsbyi strain DSM 16790
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