STRINGSTRING
A0A143ZVU1 A0A143ZVU1 A0A144A3W0 A0A144A3W0 PF3D7_0925500 PF3D7_0925500 GR3 GR3 trxr2 trxr2 prx prx PF14_0545 PF14_0545 PF3D7_0303600 PF3D7_0303600 PF3D7_0918900 PF3D7_0918900 PF3D7_0512200 PF3D7_0512200 PF3D7_1215000 PF3D7_1215000 PF3D7_1212000 PF3D7_1212000 PF3D7_0802200 PF3D7_0802200 tlp1 tlp1 PF3D7_1438900 PF3D7_1438900 GST GST PF3D7_0306300 PF3D7_0306300
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A143ZVU1Thioredoxin reductase. (541 aa)
A0A144A3W0Glutathione reductase. (546 aa)
PF3D7_0925500Thioredoxin; Belongs to the thioredoxin family. (128 aa)
GR3Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. (500 aa)
trxr2Thioredoxin reductase 2. (617 aa)
prxPeroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (240 aa)
PF14_0545Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. (104 aa)
PF3D7_0303600Plasmoredoxin. (179 aa)
PF3D7_0918900Gamma-glutamylcysteine synthetase. (1063 aa)
PF3D7_0512200Glutathione synthetase. (655 aa)
PF3D7_1215000Thioredoxin peroxidase 2. (216 aa)
PF3D7_1212000Glutathione peroxidase; Belongs to the glutathione peroxidase family. (205 aa)
PF3D7_08022001-cys peroxiredoxin. (220 aa)
tlp1Thioredoxin-like protein 1. (121 aa)
PF3D7_1438900Thioredoxin peroxidase 1. (195 aa)
GSTGlutathione S-transferase; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. (211 aa)
PF3D7_0306300Glutaredoxin 1. (111 aa)
Your Current Organism:
Plasmodium falciparum
NCBI taxonomy Id: 36329
Other names: P. falciparum 3D7, Plasmodium falciparum (isolate 3D7), Plasmodium falciparum 3D7
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.