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PF3D7_0824300 PF3D7_0824300 PF3D7_0106700 PF3D7_0106700 PF3D7_0106800 PF3D7_0106800 PF3D7_0410700 PF3D7_0410700 PF3D7_0304200 PF3D7_0304200 PF3D7_1410300 PF3D7_1410300 PF3D7_1410600 PF3D7_1410600 PF14_0159 PF14_0159 PF3D7_1423000 PF3D7_1423000 PF3D7_1431300 PF3D7_1431300 PF3D7_1435800 PF3D7_1435800 PF3D7_1436500 PF3D7_1436500 PF3D7_1442000 PF3D7_1442000 PF3D7_1442200 PF3D7_1442200 PF3D7_1450100 PF3D7_1450100 PF3D7_1451000 PF3D7_1451000 PF3D7_1451100 PF3D7_1451100 PF3D7_1451900 PF3D7_1451900 PF3D7_1459100 PF3D7_1459100 PF3D7_1462300 PF3D7_1462300 PF3D7_1475700 PF3D7_1475700 PF3D7_1003800 PF3D7_1003800 PF3D7_1034700 PF3D7_1034700 PF3D7_1037500 PF3D7_1037500 PF11_0068 PF11_0068 PF3D7_1113500 PF3D7_1113500 PF11_0207 PF11_0207 PF3D7_1123400 PF3D7_1123400 PF3D7_1144900 PF3D7_1144900 PF3D7_1145400 PF3D7_1145400 PF3D7_0422300 PF3D7_0422300 PF3D7_1312400 PF3D7_1312400 PF3D7_1330600 PF3D7_1330600 PF3D7_1348100 PF3D7_1348100 PF3D7_1348300 PF3D7_1348300 PF3D7_0110100 PF3D7_0110100 PF3D7_0414700 PF3D7_0414700 PF3D7_0416800 PF3D7_0416800 PF3D7_1357000 PF3D7_1357000 PF10_0084 PF10_0084 ARF1 ARF1 PF3D7_1117700 PF3D7_1117700 PF3D7_0807300 PF3D7_0807300 PF3D7_1310600 PF3D7_1310600 PF3D7_1320600 PF3D7_1320600 PF3D7_0903700 PF3D7_0903700 tufA tufA PF3D7_0322600 PF3D7_0322600 PF3D7_0211200 PF3D7_0211200 PF3D7_0313500 PF3D7_0313500 PF3D7_0612900 PF3D7_0612900 PF3D7_0607800 PF3D7_0607800 PF3D7_0607000 PF3D7_0607000 PF3D7_0602400 PF3D7_0602400 PF3D7_1358900 PF3D7_1358900 PF3D7_1340700 PF3D7_1340700 PF3D7_0903200 PF3D7_0903200 PF3D7_0817100 PF3D7_0817100 PF3D7_0513400 PF3D7_0513400 PF3D7_1366300 PF3D7_1366300 PF3D7_0512600 PF3D7_0512600 PF3D7_1352000 PF3D7_1352000 PF3D7_0524400 PF3D7_0524400 PF3D7_1217300 PF3D7_1217300 PF3D7_1411600 PF3D7_1411600 PF3D7_0812220 PF3D7_0812220 PF3D7_0933800 PF3D7_0933800 PF3D7_0931000 PF3D7_0931000 PF3D7_0926500 PF3D7_0926500 PF3D7_0920500 PF3D7_0920500 PF3D7_0917700 PF3D7_0917700 PFI0570w PFI0570w PF3D7_0528800 PF3D7_0528800 PF3D7_0516600 PF3D7_0516600 PF3D7_0513800 PF3D7_0513800 PF3D7_1246800 PF3D7_1246800 PF3D7_1237100 PF3D7_1237100 PF3D7_1235400 PF3D7_1235400 PF3D7_1233000 PF3D7_1233000 PF3D7_1231100 PF3D7_1231100 PF3D7_1224000 PF3D7_1224000 PF3D7_1222000 PF3D7_1222000 PF3D7_1218500 PF3D7_1218500 PF3D7_1206700 PF3D7_1206700 PF3D7_1201500 PF3D7_1201500 PF3D7_0803700 PF3D7_0803700 PF3D7_0819800 PF3D7_0819800 PF3D7_0821000 PF3D7_0821000 PF3D7_1349800 PF3D7_1349800 Adss Adss PF3D7_1359800 PF3D7_1359800 PF3D7_1366600 PF3D7_1366600 PF3D7_0715600 PF3D7_0715600 PF3D7_0723000 PF3D7_0723000 PF3D7_0827100 PF3D7_0827100
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PF3D7_0824300GTP-binding protein Obg2, putative. (773 aa)
PF3D7_0106700Small ribosomal subunit assembling AARP2 protein. (1434 aa)
PF3D7_0106800Ras-related protein Rab-5C. (214 aa)
PF3D7_0410700Ribosome biogenesis GTPase A, putative. (904 aa)
PF3D7_0304200EH domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (533 aa)
PF3D7_1410300WD repeat-containing protein, putative. (4405 aa)
PF3D7_1410600Eukaryotic translation initiation factor 2 subunit gamma, putative. (465 aa)
PF14_0159Protein SEY1 homolog; Probable GTP-binding protein that may be involved in cell development; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. RHD3 subfamily. (937 aa)
PF3D7_1423000Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (487 aa)
PF3D7_1431300Large subunit GTPase 1, putative. (833 aa)
PF3D7_1435800GTPase Era, putative. (504 aa)
PF3D7_1436500GTP-binding protein, putative. (431 aa)
PF3D7_1442000ADP-ribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family. (183 aa)
PF3D7_1442200GTP-binding protein, putative. (1000 aa)
PF3D7_1450100Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (500 aa)
PF3D7_1451000Uncharacterized protein. (804 aa)
PF3D7_1451100Elongation factor 2. (832 aa)
PF3D7_1451900Ribosome biogenesis protein TSR1, putative. (1029 aa)
PF3D7_1459100GTP-binding protein, putative. (797 aa)
PF3D7_1462300GTP-binding protein, putative. (1357 aa)
PF3D7_1475700Tubulin epsilon chain, putative; Belongs to the tubulin family. (519 aa)
PF3D7_1003800U5 small nuclear ribonucleoprotein component, putative. (1235 aa)
PF3D7_1034700ADP-ribosylation factor, putative; Belongs to the small GTPase superfamily. Arf family. (178 aa)
PF3D7_1037500Dynamin-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (709 aa)
PF11_0068RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs; Belongs to the RtcB family. (506 aa)
PF3D7_1113500GTP-binding protein, putative. (698 aa)
PF11_0207Uncharacterized protein PF11_0207. (1070 aa)
PF3D7_1123400Translation elongation factor EF-1, subunit alpha, putative. (555 aa)
PF3D7_1144900Ras-related protein Rab-6. (207 aa)
PF3D7_1145400Dynamin-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (837 aa)
PF3D7_0422300Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
PF3D7_1312400Translation initiation factor IF-2, putative. (1128 aa)
PF3D7_1330600Elongation factor Tu. (505 aa)
PF3D7_1348100GTPase, putative. (224 aa)
PF3D7_1348300Elongation factor Tu, putative. (1394 aa)
PF3D7_0110100Selenocysteine-specific elongation factor, putative. (934 aa)
PF3D7_0414700GTP-binding protein, putative. (631 aa)
PF3D7_0416800Small GTP-binding protein sar1; Belongs to the small GTPase superfamily. SAR1 family. (192 aa)
PF3D7_1357000Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (443 aa)
PF10_0084Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
ARF1ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family. (181 aa)
PF3D7_1117700GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (214 aa)
PF3D7_0807300Ras-related protein Rab-18. (201 aa)
PF3D7_1310600Ras-related protein Rab-5B. (207 aa)
PF3D7_1320600Ras-related protein Rab-11A. (216 aa)
PF3D7_0903700Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
tufAElongation factor Tu, apicoplast; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (410 aa)
PF3D7_0322600Uncharacterized protein. (1347 aa)
PF3D7_0211200Ras-related protein Rab-5A. (235 aa)
PF3D7_0313500Ras-like G protein. (911 aa)
PF3D7_0612900Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (686 aa)
PF3D7_0607800GTP-binding protein, putative. (674 aa)
PF3D7_0607000Translation initiation factor IF-2, putative. (977 aa)
PF3D7_0602400Elongation factor G. (937 aa)
PF3D7_1358900GTP-binding protein, putative. (367 aa)
PF3D7_1340700Ras-related protein Rab-11B. (229 aa)
PF3D7_0903200Ras-related protein RAB7. (206 aa)
PF3D7_0817100tRNA modification GTPase, putative. (830 aa)
PF3D7_0513400GTP-binding protein, putative. (286 aa)
PF3D7_1366300Uncharacterized protein. (4136 aa)
PF3D7_0512600Ras-related protein Rab-1B. (200 aa)
PF3D7_1352000GTP-binding protein, putative. (2006 aa)
PF3D7_0524400Ribosome-interacting GTPase 1, putative. (365 aa)
PF3D7_1217300GTP-binding protein EngA. (961 aa)
PF3D7_1411600GTP-binding protein Obg1. (658 aa)
PF3D7_0812220GTPase, putative. (293 aa)
PF3D7_0933800Tubulin delta chain, putative; Belongs to the tubulin family. (735 aa)
PF3D7_0931000Elongation factor Tu, putative. (911 aa)
PF3D7_0926500Tetratricopeptide repeat protein, putative. (1922 aa)
PF3D7_0920500ADP-ribosylation factor, putative. (191 aa)
PF3D7_0917700GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (358 aa)
PFI0570wTranslation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner (By similarity). (1085 aa)
PF3D7_0528800Nucleolar preribosomal GTPase, putative. (537 aa)
PF3D7_0516600Sporozoite surface antigen MB2. (1610 aa)
PF3D7_0513800Ras-related protein Rab-1A. (207 aa)
PF3D7_1246800Signal recognition particle receptor subunit beta, putative. (261 aa)
PF3D7_1237100Uncharacterized protein. (2792 aa)
PF3D7_1235400TetQ family GTPase, putative. (1161 aa)
PF3D7_1233000Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. (803 aa)
PF3D7_1231100Ras-related protein Rab-2. (213 aa)
PF3D7_1224000GTP cyclohydrolase 1. (389 aa)
PF3D7_1222000tRNA-splicing ligase RtcB, putative. (569 aa)
PF3D7_1218500Dynamin-like protein, putative. (1061 aa)
PF3D7_1206700Eukaryotic translation initiation factor 5, putative. (565 aa)
PF3D7_1201500GPN-loop GTPase, putative. (497 aa)
PF3D7_0803700Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (452 aa)
PF3D7_0819800TPR_REGION domain-containing protein. (1408 aa)
PF3D7_0821000Uncharacterized protein. (514 aa)
PF3D7_1349800GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (439 aa)
AdssAdenylosuccinate synthetase; Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). (442 aa)
PF3D7_1359800ADP-ribosylation factor, putative. (203 aa)
PF3D7_1366600Signal recognition particle receptor subunit alpha, putative. (576 aa)
PF3D7_0715600GTP-binding translation elongation factor tu family protein, putative. (754 aa)
PF3D7_0723000tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (299 aa)
PF3D7_0827100Translation initiation factor IF-2, putative. (1397 aa)
Your Current Organism:
Plasmodium falciparum
NCBI taxonomy Id: 36329
Other names: P. falciparum 3D7, Plasmodium falciparum (isolate 3D7), Plasmodium falciparum 3D7
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