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PF3D7_1244200 | General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (945 aa) | ||||
PF3D7_0503200 | ATPase_AAA_core domain-containing protein. (979 aa) | ||||
PF3D7_0505500 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1350 aa) | ||||
PF3D7_0508800 | Single-stranded DNA-binding protein. (284 aa) | ||||
PF3D7_0510500 | Topoisomerase I. (839 aa) | ||||
PF3D7_0511700 | EKC/KEOPS complex subunit CGI121; Belongs to the CGI121/TPRKB family. (179 aa) | ||||
PF3D7_0512300 | CDK-activating kinase assembly factor MAT1. (260 aa) | ||||
PF3D7_0514100 | ATP-dependent DNA helicase UvrD. (1441 aa) | ||||
PF3D7_0517400 | FACT complex subunit SPT16, putative. (1141 aa) | ||||
PF3D7_0521700 | ATP-dependent RNA helicase DDX1, putative. (841 aa) | ||||
PF3D7_0525200 | Structural maintenance of chromosomes protein 6, putative. (1849 aa) | ||||
PF3D7_0527000 | DNA replication licensing factor MCM3, putative; Belongs to the MCM family. (962 aa) | ||||
PF3D7_0904700 | Bacterial histone-like protein; Belongs to the bacterial histone-like protein family. (189 aa) | ||||
PF3D7_0904800 | Replication protein A1, small. (484 aa) | ||||
PF3D7_0910500 | DNA repair protein REV1, putative. (1697 aa) | ||||
PF3D7_0917100 | N-glycosylase/DNA lyase, putative. (757 aa) | ||||
PF3D7_0918600 | ATP-dependent DNA helicase Q1. (728 aa) | ||||
PF3D7_0926900 | Replication termination factor, putative. (225 aa) | ||||
PF3D7_0927700 | Serine/threonine-protein phosphatase. (312 aa) | ||||
PF3D7_0934100 | TFIIH basal transcription factor complex helicase XPD subunit. (1056 aa) | ||||
PF3D7_0110400 | DNA-directed RNA polymerase II subunit RPB9, putative. (249 aa) | ||||
PF3D7_0111300 | P-loop containing nucleoside triphosphate hydrolase, putative. (1167 aa) | ||||
PF3D7_0416300 | DNA helicase MCM9, putative; Belongs to the MCM family. (1465 aa) | ||||
PF3D7_0419300 | Rad51 domain-containing protein. (346 aa) | ||||
PF3D7_1223300 | DNA gyrase subunit A. (1222 aa) | ||||
PF14_0366 | DNA primase small subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. (452 aa) | ||||
PF3D7_1017000 | DNA polymerase. (1094 aa) | ||||
PF3D7_1226600 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (264 aa) | ||||
FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (672 aa) | ||||
PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. (274 aa) | ||||
PF3D7_0323600 | BSD domain-containing protein. (670 aa) | ||||
PF3D7_0305700 | Ubiquitin-conjugating enzyme E2, putative. (142 aa) | ||||
PF3D7_0305600 | DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (617 aa) | ||||
PF3D7_0219600 | Replication factor C subunit 1. (904 aa) | ||||
PF3D7_0218000 | Replication factor C subunit 2, putative. (330 aa) | ||||
PF3D7_0215800 | Origin recognition complex subunit 5. (899 aa) | ||||
PF3D7_0206000 | DNA repair protein RAD2, putative. (1516 aa) | ||||
PF3D7_0203900 | 5'-3' exonuclease, N-terminal resolvase-like domain, putative. (577 aa) | ||||
PF3D7_0203300 | ERCC1 nucleotide excision repair protein, putative. (242 aa) | ||||
PF3D7_0319300 | Ubiquitin-conjugating enzyme E2, putative; Belongs to the ubiquitin-conjugating enzyme family. (160 aa) | ||||
PF3D7_0317400 | DNA replication complex GINS protein, putative. (518 aa) | ||||
PF3D7_0317700 | CPSF (Cleavage and polyadenylation specific factor), subunit A, putative. (2870 aa) | ||||
PF3D7_0308600 | Pre-mRNA-processing factor 19, putative. (532 aa) | ||||
PF3D7_0308000 | DNA polymerase delta small subunit, putative. (498 aa) | ||||
PF3D7_1461500 | Meiotic nuclear division protein 1, putative; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (204 aa) | ||||
PF3D7_1027600 | Meiotic recombination protein SPO11-2, putative. (336 aa) | ||||
PF3D7_0630300 | DNA polymerase epsilon catalytic subunit A, putative. (2907 aa) | ||||
PF3D7_0628600 | DNA methyltransferase 1-associated protein 1, putative. (385 aa) | ||||
PF3D7_0625300 | DNA polymerase 1, putative. (1444 aa) | ||||
PF3D7_0624600 | SNF2 helicase, putative. (2719 aa) | ||||
PF3D7_0623900 | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (288 aa) | ||||
NTH1 | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (437 aa) | ||||
PFF0285c | Probable DNA repair protein RAD50; Essential component of the MRN complex, a complex that possesses single-stranded DNA endonuclease and 3' to 5' exonuclease activities, and plays a central role in double-strand break (DSB) repair, chromosome morphogenesis, DNA repair and meiosis. In the complex, it mediates the ATP-binding and is probably required to bind DNA ends and hold them in close proximity (By similarity). Belongs to the SMC family. RAD50 subfamily. (2236 aa) | ||||
PF3D7_0604600 | DNA helicase, putative. (1712 aa) | ||||
PF3D7_1368300 | Uncharacterized protein. (230 aa) | ||||
PF3D7_1335500 | DNA replication complex GINS protein, putative. (493 aa) | ||||
PF3D7_1331100 | DNA polymerase theta, putative. (1244 aa) | ||||
PF3D7_1316900 | Uncharacterized protein. (958 aa) | ||||
PF3D7_0910900 | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (539 aa) | ||||
PF3D7_0706700 | DNA mismatch repair protein MSH2, putative. (873 aa) | ||||
PF3D7_0505000 | MMS19-like protein, putative. (2975 aa) | ||||
PF3D7_0408400 | Uncharacterized protein. (471 aa) | ||||
PF3D7_1337500 | Uncharacterized protein. (3334 aa) | ||||
PF3D7_1334100 | Uncharacterized protein. (983 aa) | ||||
PF3D7_1319400 | Uncharacterized protein. (1070 aa) | ||||
A0A143ZZR0 | Meiotic recombination protein SPO11, putative. (307 aa) | ||||
PF3D7_1037000 | DNA polymerase zeta catalytic subunit, putative. (2226 aa) | ||||
PF3D7_1129500 | A/G-specific adenine glycosylase, putative. (611 aa) | ||||
PF3D7_0710400 | DNA repair protein RAD14, putative. (365 aa) | ||||
PF3D7_0107800 | Double-strand break repair protein MRE11. (1233 aa) | ||||
PF3D7_0409600 | Replication protein A1, large subunit. (1145 aa) | ||||
PF3D7_0411900 | DNA polymerase. (1912 aa) | ||||
PF3D7_1405400 | DNA mismatch repair protein, putative. (1515 aa) | ||||
PF3D7_1408400 | FANCJ-like helicase, putative. (1160 aa) | ||||
PF3D7_1411400 | Plastid replication-repair enzyme. (2016 aa) | ||||
PF3D7_1412100 | Mini-chromosome maintenance complex-binding protein, putative. (956 aa) | ||||
PF3D7_1415000 | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (322 aa) | ||||
PF3D7_1417800 | DNA helicase. (971 aa) | ||||
PF3D7_1425400 | DEAD/DEAH box helicase, putative. (1236 aa) | ||||
PF3D7_1427500 | DNA mismatch repair protein MSH2, putative. (811 aa) | ||||
PF3D7_1429900 | ADP-dependent DNA helicase RecQ. (1440 aa) | ||||
PF3D7_1430600 | Endonuclease/exonuclease/phosphatase family protein, putative. (876 aa) | ||||
PF3D7_1432600 | BHD_1 domain-containing protein. (1195 aa) | ||||
PF3D7_1433500 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1472 aa) | ||||
PF3D7_1437200 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (847 aa) | ||||
PF3D7_1441400 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (506 aa) | ||||
PF3D7_1449400 | Crossover junction endonuclease MUS81, putative. (1271 aa) | ||||
PF3D7_1451300 | E3 SUMO-protein ligase NSE2, putative. (229 aa) | ||||
PF3D7_1458700 | Exonuclease V, mitochondrial, putative. (353 aa) | ||||
PF3D7_1463200 | Replication factor C subunit 3, putative. (344 aa) | ||||
PF3D7_1463300 | DNA polymerase alpha subunit B, putative. (539 aa) | ||||
PF3D7_1466800 | NOC3p domain-containing protein. (902 aa) | ||||
PF3D7_1467100 | DNA-3-methyladenine glycosylase, putative. (501 aa) | ||||
PF3D7_1467500 | DNA/RNA-binding protein KIN17, putative. (442 aa) | ||||
PF3D7_1474300 | DNA repair metallo-beta-lactamase protein, putative. (860 aa) | ||||
PF3D7_1008200 | Endonuclease, putative. (388 aa) | ||||
PF3D7_1011700 | DNA repair protein RAD23, putative. (389 aa) | ||||
PF3D7_1023400 | HORMA domain protein, putative. (195 aa) | ||||
PF3D7_1037600 | TFIIH basal transcription factor complex helicase XPB subunit, putative. (886 aa) | ||||
PF3D7_1106000 | RuvB-like helicase; Belongs to the RuvB family. (475 aa) | ||||
PF3D7_1111100 | Replication factor C subunit 5, putative. (349 aa) | ||||
PF3D7_1112600 | ATPase, putative. (707 aa) | ||||
PF3D7_1117800 | DNA mismatch repair protein MLH. (1016 aa) | ||||
PF3D7_1123800 | Structural maintenance of chromosomes protein 5, putative. (1268 aa) | ||||
Q8IHX1_PLAF7 | AAA family ATPase, putative; Belongs to the AAA ATPase family. (645 aa) | ||||
PF3D7_1303800 | Uncharacterized protein. (9271 aa) | ||||
PF3D7_1304100 | DNA ligase. (912 aa) | ||||
PF3D7_1305000 | MCL1 domain-containing protein, putative. (1479 aa) | ||||
PF3D7_1314200 | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (2518 aa) | ||||
PF3D7_1314900 | General transcription factor IIH subunit. (401 aa) | ||||
PF3D7_1317100 | DNA replication licensing factor MCM4; Belongs to the MCM family. (1005 aa) | ||||
Sir2A | NAD-dependent protein deacylase Sir2A; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of medium and long chain fatty acyl groups from lysine residues. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Regulates the expression of the surface antigen-coding var genes central to the malaria pathogenesis. Cooperates with Sir2B to mediate silencing and mutual exclusive expression of only 1 of the 60 subtelomeric var genes at a time, coding for functionally different but epitopically variant versio [...] (273 aa) | ||||
PF3D7_1332600 | DNA-(Apurinic or apyrimidinic site) lyase 1, putative. (597 aa) | ||||
PF3D7_1334000 | RING zinc finger protein, putative. (445 aa) | ||||
PF3D7_1338400 | SprT-like domain-containing protein, putative. (443 aa) | ||||
PF3D7_1347100 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (710 aa) | ||||
PF3D7_1353500 | RNA polymerase II transcription factor B subunit 4, putative. (326 aa) | ||||
PF3D7_1355100 | DNA helicase; Belongs to the MCM family. (929 aa) | ||||
PF3D7_1357500 | DNA helicase, putative. (906 aa) | ||||
PF3D7_1362200 | RuvB-like helicase; Belongs to the RuvB family. (483 aa) | ||||
PF3D7_1363200 | Bifunctional polynucleotide phosphatase/kinase. (462 aa) | ||||
PF3D7_1368800 | DNA repair endonuclease XPF, putative. (1700 aa) | ||||
PF3D7_0705300 | Origin recognition complex subunit 2. (825 aa) | ||||
MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (821 aa) | ||||
PF3D7_0725000 | Exonuclease I, putative. (1347 aa) | ||||
PF3D7_0726300 | DNA mismatch repair protein PMS1, putative. (1330 aa) | ||||
PF3D7_0817900 | High mobility group protein B2. (99 aa) | ||||
PF3D7_0816800 | Meiotic recombination protein DMC1, putative; Belongs to the RecA family. (347 aa) | ||||
PF3D7_0812600 | Ubiquitin-conjugating enzyme E2, putative; Belongs to the ubiquitin-conjugating enzyme family. (163 aa) | ||||
PF3D7_0812100 | Proteasome activator complex subunit 4, putative. (2651 aa) | ||||
PF3D7_0809700 | RuvB-like helicase; Belongs to the RuvB family. (520 aa) | ||||
PF3D7_0803400 | DNA repair and recombination protein RAD54, putative. (1239 aa) | ||||
orc1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity). (1189 aa) | ||||
PF3D7_1206500 | Tat binding protein 1(TBP-1)-interacting protein, putative. (651 aa) | ||||
PF3D7_1211300 | DNA helicase MCM8, putative; Belongs to the MCM family. (1135 aa) | ||||
PF3D7_1211700 | DNA replication licensing factor MCM5, putative; Belongs to the MCM family. (758 aa) | ||||
Q8I5N7_PLAF7 | Meiotic recombination protein SPO11, putative. (327 aa) | ||||
PF3D7_1234300 | DNA polymerase epsilon subunit B, putative. (624 aa) | ||||
PF3D7_1239500 | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1006 aa) | ||||
PF3D7_1241700 | Replication factor C subunit 4, putative. (336 aa) | ||||
PF3D7_1250800 | DNA repair protein rhp16, putative. (1647 aa) |