STRINGSTRING
PF3D7_1441400 PF3D7_1441400 PF3D7_1432600 PF3D7_1432600 PF3D7_1430600 PF3D7_1430600 PF3D7_1429900 PF3D7_1429900 PF3D7_1427500 PF3D7_1427500 PF3D7_1425400 PF3D7_1425400 PF3D7_1417800 PF3D7_1417800 PF3D7_1415000 PF3D7_1415000 PF3D7_1408400 PF3D7_1408400 PF3D7_1405400 PF3D7_1405400 PF3D7_0409600 PF3D7_0409600 PF3D7_1017000 PF3D7_1017000 PF3D7_0419300 PF3D7_0419300 PF3D7_0416300 PF3D7_0416300 PF3D7_0110400 PF3D7_0110400 PF3D7_0934100 PF3D7_0934100 PF3D7_0927700 PF3D7_0927700 PF3D7_0107800 PF3D7_0107800 PF3D7_0710400 PF3D7_0710400 PF3D7_1129500 PF3D7_1129500 PF3D7_1037000 PF3D7_1037000 A0A143ZZR0 A0A143ZZR0 PF3D7_1319400 PF3D7_1319400 PF3D7_0408400 PF3D7_0408400 PF3D7_0505000 PF3D7_0505000 PF3D7_0706700 PF3D7_0706700 PF3D7_1316900 PF3D7_1316900 PF3D7_1331100 PF3D7_1331100 PF3D7_1335500 PF3D7_1335500 PF3D7_1368300 PF3D7_1368300 PF3D7_0604600 PF3D7_0604600 PFF0285c PFF0285c NTH1 NTH1 PF3D7_0623900 PF3D7_0623900 PF3D7_0624600 PF3D7_0624600 PF3D7_0625300 PF3D7_0625300 PF3D7_0628600 PF3D7_0628600 PF3D7_0630300 PF3D7_0630300 PF3D7_1027600 PF3D7_1027600 PF3D7_0308600 PF3D7_0308600 PF3D7_0317700 PF3D7_0317700 PF3D7_0317400 PF3D7_0317400 PF3D7_0319300 PF3D7_0319300 PF3D7_0203300 PF3D7_0203300 PF3D7_0203900 PF3D7_0203900 PF3D7_0206000 PF3D7_0206000 PF3D7_0218000 PF3D7_0218000 PF3D7_0219600 PF3D7_0219600 PF3D7_0305600 PF3D7_0305600 PF3D7_0305700 PF3D7_0305700 PF3D7_0323600 PF3D7_0323600 PCNA PCNA FEN1 FEN1 PF3D7_1226600 PF3D7_1226600 PF3D7_0918600 PF3D7_0918600 PF3D7_0917100 PF3D7_0917100 PF3D7_0910500 PF3D7_0910500 PF3D7_0904800 PF3D7_0904800 PF3D7_0527000 PF3D7_0527000 PF3D7_0525200 PF3D7_0525200 PF3D7_0521700 PF3D7_0521700 PF3D7_0517400 PF3D7_0517400 PF3D7_0514100 PF3D7_0514100 PF3D7_0512300 PF3D7_0512300 PF3D7_0505500 PF3D7_0505500 PF3D7_1250800 PF3D7_1250800 PF3D7_1244200 PF3D7_1244200 PF3D7_1241700 PF3D7_1241700 PF3D7_1234300 PF3D7_1234300 Q8I5N7_PLAF7 Q8I5N7_PLAF7 PF3D7_1211700 PF3D7_1211700 PF3D7_1211300 PF3D7_1211300 PF3D7_0809700 PF3D7_0809700 PF3D7_0812100 PF3D7_0812100 PF3D7_0812600 PF3D7_0812600 PF3D7_0816800 PF3D7_0816800 PF3D7_0817900 PF3D7_0817900 PF3D7_0726300 PF3D7_0726300 PF3D7_0725000 PF3D7_0725000 MCM7 MCM7 PF3D7_1368800 PF3D7_1368800 PF3D7_1363200 PF3D7_1363200 PF3D7_1362200 PF3D7_1362200 PF3D7_1357500 PF3D7_1357500 PF3D7_1355100 PF3D7_1355100 PF3D7_1353500 PF3D7_1353500 PF3D7_1338400 PF3D7_1338400 PF3D7_1332600 PF3D7_1332600 PF3D7_1317100 PF3D7_1317100 PF3D7_1314900 PF3D7_1314900 PF3D7_1305000 PF3D7_1305000 PF3D7_1304100 PF3D7_1304100 PF3D7_1123800 PF3D7_1123800 PF3D7_1117800 PF3D7_1117800 PF3D7_1112600 PF3D7_1112600 PF3D7_1111100 PF3D7_1111100 PF3D7_1106000 PF3D7_1106000 PF3D7_1037600 PF3D7_1037600 PF3D7_1023400 PF3D7_1023400 PF3D7_1011700 PF3D7_1011700 PF3D7_1008200 PF3D7_1008200 PF3D7_1474300 PF3D7_1474300 PF3D7_1467100 PF3D7_1467100 PF3D7_1463200 PF3D7_1463200 PF3D7_1451300 PF3D7_1451300 PF3D7_1449400 PF3D7_1449400
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PF3D7_1441400FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (506 aa)
PF3D7_1432600BHD_1 domain-containing protein. (1195 aa)
PF3D7_1430600Endonuclease/exonuclease/phosphatase family protein, putative. (876 aa)
PF3D7_1429900ADP-dependent DNA helicase RecQ. (1440 aa)
PF3D7_1427500DNA mismatch repair protein MSH2, putative. (811 aa)
PF3D7_1425400DEAD/DEAH box helicase, putative. (1236 aa)
PF3D7_1417800DNA helicase. (971 aa)
PF3D7_1415000Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (322 aa)
PF3D7_1408400FANCJ-like helicase, putative. (1160 aa)
PF3D7_1405400DNA mismatch repair protein, putative. (1515 aa)
PF3D7_0409600Replication protein A1, large subunit. (1145 aa)
PF3D7_1017000DNA polymerase. (1094 aa)
PF3D7_0419300Rad51 domain-containing protein. (346 aa)
PF3D7_0416300DNA helicase MCM9, putative; Belongs to the MCM family. (1465 aa)
PF3D7_0110400DNA-directed RNA polymerase II subunit RPB9, putative. (249 aa)
PF3D7_0934100TFIIH basal transcription factor complex helicase XPD subunit. (1056 aa)
PF3D7_0927700Serine/threonine-protein phosphatase. (312 aa)
PF3D7_0107800Double-strand break repair protein MRE11. (1233 aa)
PF3D7_0710400DNA repair protein RAD14, putative. (365 aa)
PF3D7_1129500A/G-specific adenine glycosylase, putative. (611 aa)
PF3D7_1037000DNA polymerase zeta catalytic subunit, putative. (2226 aa)
A0A143ZZR0Meiotic recombination protein SPO11, putative. (307 aa)
PF3D7_1319400Uncharacterized protein. (1070 aa)
PF3D7_0408400Uncharacterized protein. (471 aa)
PF3D7_0505000MMS19-like protein, putative. (2975 aa)
PF3D7_0706700DNA mismatch repair protein MSH2, putative. (873 aa)
PF3D7_1316900Uncharacterized protein. (958 aa)
PF3D7_1331100DNA polymerase theta, putative. (1244 aa)
PF3D7_1335500DNA replication complex GINS protein, putative. (493 aa)
PF3D7_1368300Uncharacterized protein. (230 aa)
PF3D7_0604600DNA helicase, putative. (1712 aa)
PFF0285cProbable DNA repair protein RAD50; Essential component of the MRN complex, a complex that possesses single-stranded DNA endonuclease and 3' to 5' exonuclease activities, and plays a central role in double-strand break (DSB) repair, chromosome morphogenesis, DNA repair and meiosis. In the complex, it mediates the ATP-binding and is probably required to bind DNA ends and hold them in close proximity (By similarity). Belongs to the SMC family. RAD50 subfamily. (2236 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (437 aa)
PF3D7_0623900Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (288 aa)
PF3D7_0624600SNF2 helicase, putative. (2719 aa)
PF3D7_0625300DNA polymerase 1, putative. (1444 aa)
PF3D7_0628600DNA methyltransferase 1-associated protein 1, putative. (385 aa)
PF3D7_0630300DNA polymerase epsilon catalytic subunit A, putative. (2907 aa)
PF3D7_1027600Meiotic recombination protein SPO11-2, putative. (336 aa)
PF3D7_0308600Pre-mRNA-processing factor 19, putative. (532 aa)
PF3D7_0317700CPSF (Cleavage and polyadenylation specific factor), subunit A, putative. (2870 aa)
PF3D7_0317400DNA replication complex GINS protein, putative. (518 aa)
PF3D7_0319300Ubiquitin-conjugating enzyme E2, putative; Belongs to the ubiquitin-conjugating enzyme family. (160 aa)
PF3D7_0203300ERCC1 nucleotide excision repair protein, putative. (242 aa)
PF3D7_02039005'-3' exonuclease, N-terminal resolvase-like domain, putative. (577 aa)
PF3D7_0206000DNA repair protein RAD2, putative. (1516 aa)
PF3D7_0218000Replication factor C subunit 2, putative. (330 aa)
PF3D7_0219600Replication factor C subunit 1. (904 aa)
PF3D7_0305600DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (617 aa)
PF3D7_0305700Ubiquitin-conjugating enzyme E2, putative. (142 aa)
PF3D7_0323600BSD domain-containing protein. (670 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. (274 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (672 aa)
PF3D7_1226600Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (264 aa)
PF3D7_0918600ATP-dependent DNA helicase Q1. (728 aa)
PF3D7_0917100N-glycosylase/DNA lyase, putative. (757 aa)
PF3D7_0910500DNA repair protein REV1, putative. (1697 aa)
PF3D7_0904800Replication protein A1, small. (484 aa)
PF3D7_0527000DNA replication licensing factor MCM3, putative; Belongs to the MCM family. (962 aa)
PF3D7_0525200Structural maintenance of chromosomes protein 6, putative. (1849 aa)
PF3D7_0521700ATP-dependent RNA helicase DDX1, putative. (841 aa)
PF3D7_0517400FACT complex subunit SPT16, putative. (1141 aa)
PF3D7_0514100ATP-dependent DNA helicase UvrD. (1441 aa)
PF3D7_0512300CDK-activating kinase assembly factor MAT1. (260 aa)
PF3D7_0505500DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1350 aa)
PF3D7_1250800DNA repair protein rhp16, putative. (1647 aa)
PF3D7_1244200General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (945 aa)
PF3D7_1241700Replication factor C subunit 4, putative. (336 aa)
PF3D7_1234300DNA polymerase epsilon subunit B, putative. (624 aa)
Q8I5N7_PLAF7Meiotic recombination protein SPO11, putative. (327 aa)
PF3D7_1211700DNA replication licensing factor MCM5, putative; Belongs to the MCM family. (758 aa)
PF3D7_1211300DNA helicase MCM8, putative; Belongs to the MCM family. (1135 aa)
PF3D7_0809700RuvB-like helicase; Belongs to the RuvB family. (520 aa)
PF3D7_0812100Proteasome activator complex subunit 4, putative. (2651 aa)
PF3D7_0812600Ubiquitin-conjugating enzyme E2, putative; Belongs to the ubiquitin-conjugating enzyme family. (163 aa)
PF3D7_0816800Meiotic recombination protein DMC1, putative; Belongs to the RecA family. (347 aa)
PF3D7_0817900High mobility group protein B2. (99 aa)
PF3D7_0726300DNA mismatch repair protein PMS1, putative. (1330 aa)
PF3D7_0725000Exonuclease I, putative. (1347 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (821 aa)
PF3D7_1368800DNA repair endonuclease XPF, putative. (1700 aa)
PF3D7_1363200Bifunctional polynucleotide phosphatase/kinase. (462 aa)
PF3D7_1362200RuvB-like helicase; Belongs to the RuvB family. (483 aa)
PF3D7_1357500DNA helicase, putative. (906 aa)
PF3D7_1355100DNA helicase; Belongs to the MCM family. (929 aa)
PF3D7_1353500RNA polymerase II transcription factor B subunit 4, putative. (326 aa)
PF3D7_1338400SprT-like domain-containing protein, putative. (443 aa)
PF3D7_1332600DNA-(Apurinic or apyrimidinic site) lyase 1, putative. (597 aa)
PF3D7_1317100DNA replication licensing factor MCM4; Belongs to the MCM family. (1005 aa)
PF3D7_1314900General transcription factor IIH subunit. (401 aa)
PF3D7_1305000MCL1 domain-containing protein, putative. (1479 aa)
PF3D7_1304100DNA ligase. (912 aa)
PF3D7_1123800Structural maintenance of chromosomes protein 5, putative. (1268 aa)
PF3D7_1117800DNA mismatch repair protein MLH. (1016 aa)
PF3D7_1112600ATPase, putative. (707 aa)
PF3D7_1111100Replication factor C subunit 5, putative. (349 aa)
PF3D7_1106000RuvB-like helicase; Belongs to the RuvB family. (475 aa)
PF3D7_1037600TFIIH basal transcription factor complex helicase XPB subunit, putative. (886 aa)
PF3D7_1023400HORMA domain protein, putative. (195 aa)
PF3D7_1011700DNA repair protein RAD23, putative. (389 aa)
PF3D7_1008200Endonuclease, putative. (388 aa)
PF3D7_1474300DNA repair metallo-beta-lactamase protein, putative. (860 aa)
PF3D7_1467100DNA-3-methyladenine glycosylase, putative. (501 aa)
PF3D7_1463200Replication factor C subunit 3, putative. (344 aa)
PF3D7_1451300E3 SUMO-protein ligase NSE2, putative. (229 aa)
PF3D7_1449400Crossover junction endonuclease MUS81, putative. (1271 aa)
Your Current Organism:
Plasmodium falciparum
NCBI taxonomy Id: 36329
Other names: P. falciparum 3D7, Plasmodium falciparum (isolate 3D7), Plasmodium falciparum 3D7
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