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PF3D7_1472200 PF3D7_1472200 PF3D7_1352200 PF3D7_1352200 PF3D7_0925700 PF3D7_0925700 PF3D7_1303400 PF3D7_1303400 PF3D7_1008000 PF3D7_1008000 Sir2B Sir2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PF3D7_1472200Histone deacetylase, putative. (2251 aa)
PF3D7_1352200U3 small nucleolar RNA-associated protein 15, putative. (464 aa)
PF3D7_0925700Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (449 aa)
PF3D7_1303400LisH domain-containing protein, putative. (1022 aa)
PF3D7_1008000Histone deacetylase 2. (2379 aa)
Sir2BNAD-dependent protein deacetylase Sir2B; Regulates the expression of the surface antigen-coding var genes central to the malaria pathogenesis. Cooperates with Sir2A to mediate silencing and mutual exclusive expression of only 1 of the 60 subtelomeric var genes at a time, coding for functionally different but epitopically variant versions of the erythrocyte membrane protein 1 (PfEMP1) molecule, to evade the detection by host immune surveillance. (1304 aa)
Your Current Organism:
Plasmodium falciparum
NCBI taxonomy Id: 36329
Other names: P. falciparum 3D7, Plasmodium falciparum (isolate 3D7), Plasmodium falciparum 3D7
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