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PF3D7_1129500 PF3D7_1129500 PF3D7_1037000 PF3D7_1037000 MAL8P1.31 MAL8P1.31 PF3D7_0910900 PF3D7_0910900 PF3D7_0930900 PF3D7_0930900 PF3D7_0606900 PF3D7_0606900 PF3D7_0614200 PF3D7_0614200 NTH1 NTH1 PF3D7_0622200 PF3D7_0622200 PF3D7_0630300 PF3D7_0630300 PF3D7_0207200 PF3D7_0207200 PF3D7_0304500 PF3D7_0304500 PF3D7_0322500 PF3D7_0322500 PF3D7_1017000 PF3D7_1017000 PF3D7_0934100 PF3D7_0934100 PF3D7_0927300 PF3D7_0927300 PF3D7_0921400 PF3D7_0921400 PF3D7_0910800 PF3D7_0910800 PF3D7_0524900 PF3D7_0524900 PF3D7_0522700 PF3D7_0522700 PF3D7_0515800 PF3D7_0515800 PF3D7_1227800 PF3D7_1227800 PF3D7_1214600 PF3D7_1214600 PF3D7_1212800 PF3D7_1212800 Q8I655_PLAF7 Q8I655_PLAF7 PF3D7_0709200 PF3D7_0709200 lipA lipA PF3D7_1342100 PF3D7_1342100 PF3D7_1318100 PF3D7_1318100 PF3D7_1128500 PF3D7_1128500 PF3D7_1022900 PF3D7_1022900 PF3D7_1022800 PF3D7_1022800 PF3D7_1458700 PF3D7_1458700 PF3D7_1454500 PF3D7_1454500 PF3D7_1439400 PF3D7_1439400 PF3D7_1435300 PF3D7_1435300 PF3D7_1429500 PF3D7_1429500 PF3D7_1413800 PF3D7_1413800 PF3D7_1408400 PF3D7_1408400 PF3D7_0302700 PF3D7_0302700
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PF3D7_1129500A/G-specific adenine glycosylase, putative. (611 aa)
PF3D7_1037000DNA polymerase zeta catalytic subunit, putative. (2226 aa)
MAL8P1.31Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] (266 aa)
PF3D7_0910900DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (539 aa)
PF3D7_0930900NifU-like protein, putative. (192 aa)
PF3D7_0606900Glutaredoxin-like protein. (219 aa)
PF3D7_0614200Cytosolic Fe-S cluster assembly factor NAR1, putative; Belongs to the NARF family. (910 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (437 aa)
PF3D7_0622200Radical SAM protein, putative. (860 aa)
PF3D7_0630300DNA polymerase epsilon catalytic subunit A, putative. (2907 aa)
PF3D7_0207200Iron-sulfur assembly protein, putative. (160 aa)
PF3D7_03045001-cys-glutaredoxin-like protein-1. (171 aa)
PF3D7_0322500Iron-sulfur assembly protein, putative. (404 aa)
PF3D7_1017000DNA polymerase. (1094 aa)
PF3D7_0934100TFIIH basal transcription factor complex helicase XPD subunit. (1056 aa)
PF3D7_0927300Fumarate hydratase. (681 aa)
PF3D7_0921400NifU-like scaffold protein. (247 aa)
PF3D7_0910800Cytosolic Fe-S cluster assembly factor NBP35, putative. (447 aa)
PF3D7_0524900S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative. (988 aa)
PF3D7_0522700Iron-sulfur assembly protein. (177 aa)
PF3D7_0515800BolA-like protein, putative; Belongs to the BolA/IbaG family. (84 aa)
PF3D7_1227800Elongator complex protein 3, putative. (1092 aa)
PF3D7_1214600Adrenodoxin-type ferredoxin, putative. (158 aa)
PF3D7_1212800Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (321 aa)
Q8I655_PLAF7Ribosome associated membrane protein RAMP4, putative. (101 aa)
PF3D7_0709200Glutaredoxin-like protein. (272 aa)
lipALipoyl synthase, apicoplast; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. (415 aa)
PF3D7_1342100Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (909 aa)
PF3D7_1318100Ferredoxin, apicoplast; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions; Belongs to the 2Fe2S plant-type ferredoxin family. (194 aa)
PF3D7_1128500Fe-S cluster assembly protein, putative. (718 aa)
PF3D7_1022900CDGSH iron-sulfur domain-containing protein, putative. (118 aa)
PF3D7_10228004-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (Ferredoxin), putative. (824 aa)
PF3D7_1458700Exonuclease V, mitochondrial, putative. (353 aa)
PF3D7_1454500Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (162 aa)
PF3D7_1439400Cytochrome b-c1 complex subunit Rieske, putative. (355 aa)
PF3D7_1435300Glutamate synthase [NADH], putative. (3106 aa)
PF3D7_1429500Diphthamide biosynthesis protein 2, putative. (744 aa)
PF3D7_14138002-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (487 aa)
PF3D7_1408400FANCJ-like helicase, putative. (1160 aa)
PF3D7_0302700CDGSH iron-sulfur domain-containing protein, putative. (152 aa)
Your Current Organism:
Plasmodium falciparum
NCBI taxonomy Id: 36329
Other names: P. falciparum 3D7, Plasmodium falciparum (isolate 3D7), Plasmodium falciparum 3D7
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