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PF3D7_0903100 PF3D7_0903100 PF3D7_0905900 PF3D7_0905900 PF3D7_0906100 PF3D7_0906100 PF3D7_0935200 PF3D7_0935200 PF3D7_0103900 PF3D7_0103900 PF3D7_0106100 PF3D7_0106100 PF3D7_0413500 PF3D7_0413500 PF3D7_0415400 PF3D7_0415400 PF3D7_0416800 PF3D7_0416800 PF3D7_0418500 PF3D7_0418500 PF14_0076 PF14_0076 vapA vapA PF3D7_0406100 PF3D7_0406100 PF3D7_0322600 PF3D7_0322600 PF3D7_0217300 PF3D7_0217300 PF3D7_0216400 PF3D7_0216400 PF3D7_0214100 PF3D7_0214100 PF3D7_0212000 PF3D7_0212000 PF3D7_0210000 PF3D7_0210000 PF3D7_0625100 PF3D7_0625100 C6KT86_PLAF7 C6KT86_PLAF7 C6KT30_PLAF7 C6KT30_PLAF7 PF3D7_0617100 PF3D7_0617100 PF3D7_0617000 PF3D7_0617000 PF3D7_0606700 PF3D7_0606700 PF3D7_0603500 PF3D7_0603500 PF3D7_1361100 PF3D7_1361100 PF3D7_1344100 PF3D7_1344100 PF3D7_0935100 PF3D7_0935100 C0H526_PLAF7 C0H526_PLAF7 PF3D7_0821800 PF3D7_0821800 PF3D7_0808400 PF3D7_0808400 PF3D7_0808100 PF3D7_0808100 PF3D7_0802500 PF3D7_0802500 PF3D7_0405100 PF3D7_0405100 PF3D7_0103000 PF3D7_0103000 PF3D7_1366300 PF3D7_1366300 PF3D7_1243500 PF3D7_1243500 A0A143ZZP8 A0A143ZZP8 A0A143ZY06 A0A143ZY06 A0A143ZX45 A0A143ZX45 A0A143ZX23 A0A143ZX23 A0A143ZWB4 A0A143ZWB4 PF3D7_0608310 PF3D7_0608310 A0A143ZVB5 A0A143ZVB5 PF3D7_0113000 PF3D7_0113000 PF3D7_0304200 PF3D7_0304200 PF3D7_1407800 PF3D7_1407800 PF3D7_1408100 PF3D7_1408100 PF3D7_1410300 PF3D7_1410300 PF3D7_1429800 PF3D7_1429800 PF3D7_1456800 PF3D7_1456800 PF3D7_1457500 PF3D7_1457500 PF3D7_1458900 PF3D7_1458900 PF3D7_1464700 PF3D7_1464700 Q8IJT3_PLAF7 Q8IJT3_PLAF7 PF3D7_1019900 PF3D7_1019900 PF3D7_1025400 PF3D7_1025400 PF3D7_1034000 PF3D7_1034000 PF3D7_1110500 PF3D7_1110500 PF3D7_1111300 PF3D7_1111300 PF3D7_1113300 PF3D7_1113300 PF3D7_1134800 PF3D7_1134800 PF3D7_1145100 PF3D7_1145100 Q8IET3_PLAF7 Q8IET3_PLAF7 PF3D7_1306600 PF3D7_1306600 PF3D7_1309700 PF3D7_1309700 PF3D7_1322500 PF3D7_1322500 PF3D7_1323200 PF3D7_1323200 PF3D7_1332000 PF3D7_1332000 PF3D7_1346100 PF3D7_1346100 PF3D7_1348100 PF3D7_1348100 PF3D7_1354400 PF3D7_1354400 PF3D7_1366600 PF3D7_1366600 CG10 CG10 PF3D7_0716900 PF3D7_0716900 PF3D7_0719100 PF3D7_0719100 PF3D7_0727000 PF3D7_0727000 pfsec23 pfsec23 PF3D7_0821000 PF3D7_0821000 PF3D7_0820500 PF3D7_0820500 PF3D7_0819800 PF3D7_0819800 PF3D7_0806800 PF3D7_0806800 PF3D7_0804900 PF3D7_0804900 PF3D7_1408000 PF3D7_1408000 PF3D7_1218300 PF3D7_1218300 PF3D7_1219100 PF3D7_1219100 PF3D7_1223700 PF3D7_1223700 PF3D7_1225700 PF3D7_1225700 PF3D7_1226400 PF3D7_1226400 PF3D7_1230700 PF3D7_1230700 PF3D7_1235200 PF3D7_1235200 PF3D7_1236000 PF3D7_1236000 PF3D7_1237100 PF3D7_1237100 PF3D7_1239900 PF3D7_1239900 PF3D7_1242000 PF3D7_1242000 PF3D7_1244600 PF3D7_1244600 PF3D7_1245800 PF3D7_1245800 PF3D7_1246300 PF3D7_1246300 PF3D7_1246800 PF3D7_1246800 PF3D7_0505300 PF3D7_0505300 PF3D7_0529700 PF3D7_0529700
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PF3D7_0903100Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment. (201 aa)
PF3D7_0905900Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (1010 aa)
PF3D7_0906100Vacuolar protein sorting-associated protein 46, putative. (195 aa)
PF3D7_0935200Vacuolar protein sorting-associated protein 33, putative; Belongs to the STXBP/unc-18/SEC1 family. (1147 aa)
PF3D7_0103900Parasite-infected erythrocyte surface protein. (575 aa)
PF3D7_0106100V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (383 aa)
PF3D7_0413500Phosphoglucomutase-2. (295 aa)
PF3D7_0415400Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (208 aa)
PF3D7_0416800Small GTP-binding protein sar1; Belongs to the small GTPase superfamily. SAR1 family. (192 aa)
PF3D7_0418500Trafficking protein particle complex subunit; May play a role in vesicular transport from endoplasmic reticulum to Golgi. (187 aa)
PF14_0076Plasmepsin-1; Participates in the digestion of the host hemoglobin. Initial cleavage at the hinge region of hemoglobin, than cleaves at other sites, leading to denaturation of the molecule and to further degradation (By similarity); Belongs to the peptidase A1 family. (452 aa)
vapAV-type proton ATPase catalytic subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells; Belongs to the ATPase alpha/beta chains family. (611 aa)
PF3D7_0406100Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (494 aa)
PF3D7_0322600Uncharacterized protein. (1347 aa)
PF3D7_0217300AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (141 aa)
PF3D7_0216400Vacuolar protein sorting-associated protein 45; Belongs to the STXBP/unc-18/SEC1 family. (722 aa)
PF3D7_0214100Protein transport protein SEC31. (1471 aa)
PF3D7_0212000GDP-fructose:GMP antiporter, putative. (311 aa)
PF3D7_0210000Secretory complex protein 61 gamma subunit. (81 aa)
PF3D7_0625100Sphingomyelin synthase 2, putative. (399 aa)
C6KT86_PLAF7Sphingomyelin synthase 1, putative. (461 aa)
C6KT30_PLAF7FPL domain-containing protein. (1796 aa)
PF3D7_0617100AP-2 complex subunit alpha, putative. (1236 aa)
PF3D7_0617000Mitochondrial import receptor subunit TOM40, putative. (377 aa)
PF3D7_0606700Coatomer alpha subunit, putative. (1512 aa)
PF3D7_0603500Cation/H+ antiporter; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (441 aa)
PF3D7_1361100Protein transport protein Sec24A. (940 aa)
PF3D7_1344100TLD domain-containing protein, putative. (805 aa)
PF3D7_0935100Protein kish; Involved in the early part of the secretory pathway. (72 aa)
C0H526_PLAF7DUF1084 domain-containing protein. (305 aa)
PF3D7_0821800Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (80 aa)
PF3D7_0808400Coatomer subunit epsilon, putative. (278 aa)
PF3D7_0808100AP-3 complex subunit delta, putative. (1609 aa)
PF3D7_0802500Inositol 5-phosphatase, putative. (1419 aa)
PF3D7_0405100Protein transport protein Sec24B, putative. (1350 aa)
PF3D7_0103000Vacuolar protein sorting-associated protein VTA1, putative. (259 aa)
PF3D7_1366300Uncharacterized protein. (4136 aa)
PF3D7_1243500Vacuolar-sorting protein SNF7, putative. (226 aa)
A0A143ZZP8DUF1084 domain-containing protein. (263 aa)
A0A143ZY06Vesicle transport v-SNARE protein, putative. (70 aa)
A0A143ZX45FPL domain-containing protein. (1797 aa)
A0A143ZX23Vesicle transport v-SNARE protein, putative. (198 aa)
A0A143ZWB4SNARE protein, putative. (172 aa)
PF3D7_0608310Sorting assembly machinery 50 kDa subunit, putative. (453 aa)
A0A143ZVB5Sphingomyelin synthase 1, putative. (439 aa)
PF3D7_0113000Glutamic acid-rich protein GARP. (673 aa)
PF3D7_0304200EH domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (533 aa)
PF3D7_1407800Plasmepsin IV; Belongs to the peptidase A1 family. (449 aa)
PF3D7_1408100Plasmepsin III; Belongs to the peptidase A1 family. (451 aa)
PF3D7_1410300WD repeat-containing protein, putative. (4405 aa)
PF3D7_1429800Coatomer subunit beta, putative. (1370 aa)
PF3D7_1456800V-type H(+)-translocating pyrophosphatase, putative. (717 aa)
PF3D7_1457500Vacuolar protein sorting-associated protein 4; Belongs to the AAA ATPase family. (419 aa)
PF3D7_1458900Golgi apparatus membrane protein TVP23 homolog. (230 aa)
PF3D7_1464700V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (382 aa)
Q8IJT3_PLAF7BET1-like protein, putative. (114 aa)
PF3D7_1019900Autophagy-related protein; Belongs to the ATG8 family. (124 aa)
PF3D7_1025400Uncharacterized protein. (1358 aa)
PF3D7_1034000Sec1 family protein, putative; Belongs to the STXBP/unc-18/SEC1 family. (663 aa)
PF3D7_1110500Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (1050 aa)
PF3D7_1111300Protein transport protein BOS1, putative. (289 aa)
PF3D7_1113300UDP-galactose transporter, putative. (343 aa)
PF3D7_1134800Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (487 aa)
PF3D7_1145100Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (1068 aa)
Q8IET3_PLAF7SNARE protein, putative; Belongs to the synaptobrevin family. (208 aa)
PF3D7_1306600V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (455 aa)
PF3D7_1309700Vacuolar protein sorting-associated protein 18, putative. (1672 aa)
PF3D7_1322500Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (676 aa)
PF3D7_1323200V-type proton ATPase subunit G, putative. (123 aa)
PF3D7_1332000Syntaxin, Qa-SNARE family. (281 aa)
PF3D7_1346100Protein transport protein SEC61 subunit alpha. (472 aa)
PF3D7_1348100GTPase, putative. (224 aa)
PF3D7_1354400V-type proton ATPase 21 kDa proteolipid subunit, putative; Belongs to the V-ATPase proteolipid subunit family. (181 aa)
PF3D7_1366600Signal recognition particle receptor subunit alpha, putative. (576 aa)
CG10Putative chloroquine resistance transporter; May regulate endogenous transporter; Belongs to the CRT-like transporter family. (424 aa)
PF3D7_0716900Drug/metabolite transporter DMT2. (322 aa)
PF3D7_0719100ATP synthase F0 subunit a-like protein, putative. (179 aa)
PF3D7_0727000Vacuolar protein sorting-associated protein 53, putative. (1162 aa)
pfsec23Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (759 aa)
PF3D7_0821000Uncharacterized protein. (514 aa)
PF3D7_0820500Protein transport protein YIF1, putative. (852 aa)
PF3D7_0819800TPR_REGION domain-containing protein. (1408 aa)
PF3D7_0806800V-type proton ATPase subunit a, putative. (1053 aa)
PF3D7_0804900GTPase-activating protein, putative. (491 aa)
PF3D7_1408000Plasmepsin II; Belongs to the peptidase A1 family. (453 aa)
PF3D7_1218300AP-2 complex subunit mu, putative; Belongs to the adaptor complexes medium subunit family. (621 aa)
PF3D7_1219100Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1997 aa)
PF3D7_1223700Vacuolar iron transporter. (273 aa)
PF3D7_1225700VAC14 domain-containing protein, putative. (1501 aa)
PF3D7_1226400Mic1 domain-containing protein. (856 aa)
PF3D7_1230700Protein transport protein SEC13; Belongs to the WD repeat SEC13 family. (822 aa)
PF3D7_1235200V-type K+-independent H+-translocating inorganic pyrophosphatase. (1057 aa)
PF3D7_1236000Vesicle transport v-SNARE protein VTI1, putative. (410 aa)
PF3D7_1237100Uncharacterized protein. (2792 aa)
PF3D7_1239900Vacuolar protein sorting-associated protein 16, putative. (1032 aa)
PF3D7_1242000Sulfhydryl oxidase. (531 aa)
PF3D7_1244600ADP-ribosylation factor GTPase-activating protein. (332 aa)
PF3D7_1245800Epsin-like protein, putative. (431 aa)
PF3D7_1246300Clathrin adaptor domain-containing protein, putative. (888 aa)
PF3D7_1246800Signal recognition particle receptor subunit beta, putative. (261 aa)
PF3D7_0505300UDP-N-acetylglucosamine transporter, putative. (611 aa)
PF3D7_0529700Heptatricopeptide repeat-containing protein, putative. (986 aa)
Your Current Organism:
Plasmodium falciparum
NCBI taxonomy Id: 36329
Other names: P. falciparum 3D7, Plasmodium falciparum (isolate 3D7), Plasmodium falciparum 3D7
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