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PF3D7_0934800 PF3D7_0934800 PF3D7_0821100 PF3D7_0821100 PF3D7_0312400 PF3D7_0312400 CRK2 CRK2 PF14_0323 PF14_0323 CPK4 CPK4 CPK2 CPK2 CK1 CK1 PF3D7_1445400 PF3D7_1445400 PF3D7_1418300 PF3D7_1418300 CPK3 CPK3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PF3D7_0934800cAMP-dependent protein kinase catalytic subunit; Belongs to the protein kinase superfamily. (342 aa)
PF3D7_0821100Protein kinase 1. (918 aa)
PF3D7_0312400Glycogen synthase kinase 3; Belongs to the protein kinase superfamily. (440 aa)
CRK2Cell division control protein 2 homolog; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II (By similarity). (288 aa)
PF14_0323Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
CPK4Calcium-dependent protein kinase 4; Calcium-dependent kinase that plays a central role in the sexual reproduction and mosquito transmission of P.falciparum. Required for cell cycle progression in the male gametocyte, an essential step in parasite transmission to the mosquito (By similarity). (528 aa)
CPK2Calcium-dependent protein kinase 2; Calcium-dependent kinase that may play a role in mosquito transmission of P.falciparum; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. (509 aa)
CK1Casein kinase I; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins (By similarity). (323 aa)
PF3D7_1445400Protein serine/threonine kinase-1. (881 aa)
PF3D7_1418300Calmodulin, putative. (136 aa)
CPK3Calcium-dependent protein kinase 3; Calcium-dependent kinase that may play a role in the sexual reproduction and mosquito transmission of P.falciparum. (562 aa)
Your Current Organism:
Plasmodium falciparum
NCBI taxonomy Id: 36329
Other names: P. falciparum 3D7, Plasmodium falciparum (isolate 3D7), Plasmodium falciparum 3D7
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