(4 nodes) JAB/MPN domain network (Plasmodium falciparum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PF3D7_0912900	26S proteasome regulatory subunit RPN8, putative. (338 aa)
	PF3D7_0918300	Eukaryotic translation initiation factor 3 subunit F, putative; Belongs to the eIF-3 subunit F family. (320 aa)
	PF3D7_0405400	Pre-mRNA-processing-splicing factor 8, putative. (3136 aa)
	PF3D7_1368100	26S proteasome regulatory subunit RPN11, putative. (311 aa)

Your Current Organism:

Plasmodium falciparum

NCBI taxonomy Id: 36329
Other names: P. falciparum 3D7, Plasmodium falciparum (isolate 3D7), Plasmodium falciparum 3D7

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PF3D7_0912900	PF3D7_1368100	Q8I323	Q8ID28	26S proteasome regulatory subunit RPN8, putative.	26S proteasome regulatory subunit RPN11, putative.	0.999
PF3D7_0918300	PF3D7_1368100	Q8I2X0	Q8ID28	Eukaryotic translation initiation factor 3 subunit F, putative; Belongs to the eIF-3 subunit F family.	26S proteasome regulatory subunit RPN11, putative.	0.583
PF3D7_1368100	PF3D7_0912900	Q8ID28	Q8I323	26S proteasome regulatory subunit RPN11, putative.	26S proteasome regulatory subunit RPN8, putative.	0.999
PF3D7_1368100	PF3D7_0918300	Q8ID28	Q8I2X0	26S proteasome regulatory subunit RPN11, putative.	Eukaryotic translation initiation factor 3 subunit F, putative; Belongs to the eIF-3 subunit F family.	0.583