STRINGSTRING
LOC107950998 LOC107950998 LOC107886366 LOC107886366 LOC107886465 LOC107886465 LOC107886809 LOC107886809 LOC107886941 LOC107886941 LOC107887072 LOC107887072 LOC107887081 LOC107887081 LOC107887093 LOC107887093 LOC107887454 LOC107887454 LOC107887527 LOC107887527 LOC107887792 LOC107887792 LOC107887840 LOC107887840 LOC107887837 LOC107887837 LOC107888376 LOC107888376 LOC107888434 LOC107888434 LOC107888453 LOC107888453 LOC107886349 LOC107886349 LOC107889028 LOC107889028 LOC107889593 LOC107889593 LOC107888356 LOC107888356 LOC107887642 LOC107887642 LOC107890121 LOC107890121 LOC107890150 LOC107890150 LOC107888519 LOC107888519 LOC107890466 LOC107890466 LOC107888357 LOC107888357 LOC107891155 LOC107891155 LOC107891200 LOC107891200 LOC107891761 LOC107891761 LOC107891924 LOC107891924 LOC107892362 LOC107892362 LOC107890889 LOC107890889 LOC107892428 LOC107892428 LOC107890755 LOC107890755 LOC107893417 LOC107893417 LOC107893502 LOC107893502 LOC107894047 LOC107894047 LOC107894042 LOC107894042 LOC107892338 LOC107892338 LOC107894454 LOC107894454 LOC107894587 LOC107894587 LOC107893353 LOC107893353 LOC107895100 LOC107895100 LOC107893426 LOC107893426 LOC107893503 LOC107893503 LOC107893414 LOC107893414 LOC107895547 LOC107895547 LOC107893482 LOC107893482 LOC107893529 LOC107893529 LOC107893906 LOC107893906 LOC107894311 LOC107894311 LOC107894237 LOC107894237 LOC107896663 LOC107896663 LOC107894612 LOC107894612 LOC107895222 LOC107895222 LOC107895311 LOC107895311 LOC107896297 LOC107896297 LOC107896560 LOC107896560 LOC107897934 LOC107897934 LOC107896602 LOC107896602 LOC107898066 LOC107898066 LOC107898487 LOC107898487 LOC107898675 LOC107898675 LOC107896662 LOC107896662 LOC107899067 LOC107899067 LOC107899100 LOC107899100 LOC107899196 LOC107899196 LOC107897258 LOC107897258 LOC107899400 LOC107899400 LOC107898021 LOC107898021 LOC107899563 LOC107899563 LOC107898825 LOC107898825 LOC107900442 LOC107900442 LOC107900993 LOC107900993 LOC107901388 LOC107901388 LOC107899677 LOC107899677 LOC107902163 LOC107902163 LOC107903422 LOC107903422 LOC107901771 LOC107901771 LOC107901984 LOC107901984 LOC107904187 LOC107904187 LOC107902799 LOC107902799 LOC107902878 LOC107902878 LOC107904365 LOC107904365 LOC107903179 LOC107903179 LOC107903900 LOC107903900 LOC107905313 LOC107905313 LOC107903981 LOC107903981 LOC107905873 LOC107905873 LOC107904881 LOC107904881 LOC107906483 LOC107906483 LOC107906690 LOC107906690 LOC107907069 LOC107907069 LOC107907498 LOC107907498 LOC107907813 LOC107907813 LOC107908075 LOC107908075 LOC107908141 LOC107908141 LOC107908531 LOC107908531 LOC107909120 LOC107909120 LOC107907353 LOC107907353 LOC107909874 LOC107909874 LOC107909976 LOC107909976 LOC107910013 LOC107910013 LOC107909093 LOC107909093 LOC107910270 LOC107910270 LOC107908838 LOC107908838 LOC107910657 LOC107910657 LOC107910656 LOC107910656 LOC107911002 LOC107911002 LOC107911576 LOC107911576 LOC107911799 LOC107911799 LOC107912226 LOC107912226 LOC107912324 LOC107912324 LOC107912858 LOC107912858 LOC107911501 LOC107911501 LOC107911801 LOC107911801 LOC107913171 LOC107913171 LOC107913234 LOC107913234 LOC107913539 LOC107913539 LOC107913572 LOC107913572 LOC107913609 LOC107913609 LOC107912765 LOC107912765 LOC107914195 LOC107914195 LOC107914740 LOC107914740 LOC107914874 LOC107914874 LOC107913776 LOC107913776 LOC107915273 LOC107915273 LOC107914194 LOC107914194 LOC107916232 LOC107916232 LOC107916254 LOC107916254 LOC107916648 LOC107916648 LOC107915421 LOC107915421 LOC107917216 LOC107917216 LOC107917795 LOC107917795 LOC107916626 LOC107916626 LOC107918200 LOC107918200 LOC107918386 LOC107918386 LOC107916885 LOC107916885 LOC107917326 LOC107917326 LOC107918725 LOC107918725 LOC107918722 LOC107918722 LOC107918535 LOC107918535 LOC107920678 LOC107920678 LOC107920789 LOC107920789 LOC107919835 LOC107919835 LOC107921247 LOC107921247 LOC107921785 LOC107921785 LOC107920673 LOC107920673 LOC107920927 LOC107920927 LOC107921384 LOC107921384 LOC107922502 LOC107922502 LOC107923010 LOC107923010 LOC107923086 LOC107923086 LOC107923182 LOC107923182 LOC107923222 LOC107923222 LOC107922452 LOC107922452 LOC107922612 LOC107922612 LOC107922471 LOC107922471 LOC107922673 LOC107922673 LOC107922782 LOC107922782 LOC107924104 LOC107924104 LOC107924261 LOC107924261 LOC107924100 LOC107924100 LOC107925060 LOC107925060 LOC107925199 LOC107925199 LOC107925577 LOC107925577 LOC107925687 LOC107925687 LOC107924650 LOC107924650 LOC107925722 LOC107925722 LOC107925403 LOC107925403 LOC107925704 LOC107925704 LOC107927137 LOC107927137 LOC107927203 LOC107927203 LOC107927240 LOC107927240 LOC107927582 LOC107927582 LOC107926968 LOC107926968 LOC107928309 LOC107928309 LOC107927308 LOC107927308 LOC107928346 LOC107928346 LOC107927199 LOC107927199 LOC107928765 LOC107928765 LOC107927807 LOC107927807 LOC107929188 LOC107929188 LOC107930034 LOC107930034 LOC107928922 LOC107928922 LOC107930162 LOC107930162 LOC107931409 LOC107931409 LOC107932759 LOC107932759 LOC107932837 LOC107932837 LOC107931848 LOC107931848 LOC107932814 LOC107932814 LOC107932564 LOC107932564 LOC107933321 LOC107933321 LOC107934367 LOC107934367 LOC107934411 LOC107934411 LOC107935553 LOC107935553 LOC107935704 LOC107935704 LOC107934693 LOC107934693 LOC107936368 LOC107936368 LOC107936538 LOC107936538 LOC107935512 LOC107935512 LOC107936712 LOC107936712 LOC107936782 LOC107936782 LOC107935920 LOC107935920 LOC107936991 LOC107936991 LOC107937263 LOC107937263 LOC107937350 LOC107937350 LOC107937412 LOC107937412 LOC107937909 LOC107937909 LOC107938642 LOC107938642 LOC107938861 LOC107938861 LOC107937850 LOC107937850 LOC107937970 LOC107937970 LOC107937982 LOC107937982 LOC107939484 LOC107939484 LOC107938485 LOC107938485 LOC107938484 LOC107938484 LOC107940023 LOC107940023 LOC107940281 LOC107940281 LOC107940679 LOC107940679 LOC107940857 LOC107940857 LOC107940962 LOC107940962 LOC107941224 LOC107941224 LOC107941239 LOC107941239 LOC107941566 LOC107941566 LOC107940484 LOC107940484 LOC107940558 LOC107940558 LOC107942638 LOC107942638 LOC107941655 LOC107941655 LOC107943530 LOC107943530 LOC107943553 LOC107943553 LOC107942736 LOC107942736 LOC107943472 LOC107943472 LOC107944775 LOC107944775 LOC107943937 LOC107943937 LOC107943981 LOC107943981 LOC107945355 LOC107945355 LOC107944611 LOC107944611 LOC107946806 LOC107946806 LOC107947091 LOC107947091 LOC107947324 LOC107947324 LOC107946589 LOC107946589 LOC107948266 LOC107948266 LOC107947115 LOC107947115 LOC107948426 LOC107948426 LOC107948418 LOC107948418 LOC107948535 LOC107948535 LOC107947368 LOC107947368 LOC107947329 LOC107947329 LOC107948602 LOC107948602 LOC107948791 LOC107948791 LOC107949298 LOC107949298 LOC107948805 LOC107948805 LOC107949761 LOC107949761 LOC107949785 LOC107949785 LOC107949799 LOC107949799 LOC107950350 LOC107950350 LOC107950364 LOC107950364 LOC107949689 LOC107949689 LOC107950594 LOC107950594 LOC107950214 LOC107950214 LOC107963759 LOC107963759 LOC107963291 LOC107963291 LOC107962295 LOC107962295 LOC107961644 LOC107961644 LOC107960241 LOC107960241 LOC107960652 LOC107960652 LOC107959344 LOC107959344 LOC107959946 LOC107959946 LOC107959376 LOC107959376 LOC107959354 LOC107959354 LOC107956541 LOC107956541 LOC107957481 LOC107957481 LOC107955444 LOC107955444 LOC107955654 LOC107955654 LOC107955470 LOC107955470 LOC107953799 LOC107953799 LOC107953585 LOC107953585 LOC107953645 LOC107953645 LOC107953562 LOC107953562 LOC107952113 LOC107952113 LOC107951878 LOC107951878 LOC107951716 LOC107951716
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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LOC107950998DNA polymerase I-like isoform X1. (347 aa)
LOC107886366Probable DNA primase large subunit. (452 aa)
LOC107886465FACT complex subunit SPT16-like. (1065 aa)
LOC107886809Transcription factor-like protein DPB isoform X1; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family. (353 aa)
LOC107886941DNA polymerase kappa-like isoform X1. (662 aa)
LOC107887072WD repeat and HMG-box DNA-binding protein 1-like isoform X1. (978 aa)
LOC107887081ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (611 aa)
LOC107887093Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (626 aa)
LOC107887454Origin of replication complex subunit 5-like. (533 aa)
LOC107887527DNA ligase 1-like; Belongs to the ATP-dependent DNA ligase family. (248 aa)
LOC107887792Protein OSB1, mitochondrial-like. (205 aa)
LOC107887840Uncharacterized protein LOC107887840. (242 aa)
LOC107887837DNA annealing helicase and endonuclease ZRANB3-like. (1318 aa)
LOC107888376Replication protein A 32 kDa subunit A-like isoform X1. (282 aa)
LOC107888434Protein RTF2 homolog. (343 aa)
LOC107888453DNA helicase; Belongs to the MCM family. (935 aa)
LOC107886349TIMELESS-interacting protein-like; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (338 aa)
LOC107889028Protein STICHEL-like 3. (1174 aa)
LOC107889593Transcription factor-like protein DPB isoform X1; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family. (353 aa)
LOC107888356FACT complex subunit SPT16-like. (1069 aa)
LOC107887642ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (882 aa)
LOC107890121Uncharacterized protein LOC107890121. (122 aa)
LOC107890150Uncharacterized protein LOC107890150. (704 aa)
LOC107888519DNA helicase; Belongs to the MCM family. (935 aa)
LOC107890466DNA replication licensing factor MCM5-like isoform X1; Belongs to the MCM family. (291 aa)
LOC107888357FACT complex subunit SPT16-like. (1064 aa)
LOC107891155Transcription factor-like protein DPB isoform X1; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family. (353 aa)
LOC107891200Replication factor C subunit 3 isoform X1. (354 aa)
LOC107891761Protein STICHEL-like 3. (1171 aa)
LOC107891924E3 ubiquitin-protein ligase UPL3-like. (1906 aa)
LOC107892362FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (639 aa)
LOC107890889Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (807 aa)
LOC107892428DNA replication licensing factor MCM5-like. (315 aa)
LOC107890755Uncharacterized protein LOC107890755. (994 aa)
LOC107893417DNA helicase; Belongs to the MCM family. (734 aa)
LOC107893502FACT complex subunit SPT16-like. (1070 aa)
LOC107894047Single-stranded DNA-binding protein, mitochondrial-like isoform X1. (214 aa)
LOC107894042Uncharacterized protein YpgQ-like isoform X1. (228 aa)
LOC107892338FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (639 aa)
LOC107894454RING-H2 zinc finger protein RHA1a-like. (112 aa)
LOC107894587FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (101 aa)
LOC107893353LOW QUALITY PROTEIN: replication protein A 70 kDa DNA-binding subunit A-like. (550 aa)
LOC107895100Uncharacterized protein LOC107895100 isoform X1. (1371 aa)
LOC107893426Protein RTF2 homolog. (343 aa)
LOC107893503FACT complex subunit SPT16-like. (1064 aa)
LOC107893414LOW QUALITY PROTEIN: helicase and polymerase-containing protein TEBICHI-like. (2166 aa)
LOC107895547ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (733 aa)
LOC107893482Replication protein A 32 kDa subunit A-like isoform X1. (281 aa)
LOC107893529DNA polymerase. (1097 aa)
LOC107893906FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (99 aa)
LOC107894311DNA polymerase. (1960 aa)
LOC107894237ATP-dependent DNA helicase Q-like 4A isoform X1. (1222 aa)
LOC107896663Protein STICHEL-like isoform X1. (1316 aa)
LOC107894612Origin of replication complex subunit 6-like. (325 aa)
LOC107895222DNA polymerase IV-like isoform X1. (113 aa)
LOC107895311Protein ROOT INITIATION DEFECTIVE 3-like. (411 aa)
LOC107896297DNA replication ATP-dependent helicase/nuclease DNA2-like isoform X1. (1363 aa)
LOC107896560Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (383 aa)
LOC107897934DNA polymerase. (1531 aa)
LOC107896602DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (231 aa)
LOC107898066Origin of replication complex subunit 2-like. (261 aa)
LOC107898487Flap endonuclease 1-like isoform X1. (96 aa)
LOC107898675Protein OSB3, chloroplastic/mitochondrial-like. (330 aa)
LOC107896662Zinc finger protein 830-like. (379 aa)
LOC107899067Single-stranded DNA-binding protein, mitochondrial isoform X1. (214 aa)
LOC107899100DNA polymerase zeta catalytic subunit-like. (2042 aa)
LOC107899196Protein downstream neighbor of Son-like. (620 aa)
LOC107897258Nucleolar and coiled-body phosphoprotein 1-like. (526 aa)
LOC107899400Origin of replication complex subunit 2-like. (149 aa)
LOC107898021DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (623 aa)
LOC107899563Transcription factor bHLH140 isoform X1. (700 aa)
LOC107898825LOW QUALITY PROTEIN: origin of replication complex subunit 2-like. (364 aa)
LOC107900442DNA replication complex GINS protein PSF3-like isoform X1. (185 aa)
LOC107900993DNA repair protein RAD51 homolog. (204 aa)
LOC107901388Replication factor C subunit 4. (342 aa)
LOC107899677DNA polymerase delta small subunit-like. (439 aa)
LOC107902163Protein TONSOKU-like. (1347 aa)
LOC107903422DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (901 aa)
LOC107901771SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1. (714 aa)
LOC107901984DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (536 aa)
LOC107904187Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (313 aa)
LOC107902799Replication protein A 32 kDa subunit A-like. (344 aa)
LOC107902878Replication protein A 32 kDa subunit B-like. (263 aa)
LOC107904365Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (297 aa)
LOC107903179Uncharacterized protein LOC107903179 isoform X1. (107 aa)
LOC107903900DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (623 aa)
LOC107905313Transcription factor-like protein DPB isoform X1; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family. (353 aa)
LOC107903981DNA topoisomerase 2-binding protein 1-A-like isoform X1. (985 aa)
LOC107905873DNA helicase; Belongs to the MCM family. (758 aa)
LOC107904881DNA polymerase I-like isoform X1. (435 aa)
LOC107906483Probable DNA replication complex GINS protein PSF1 isoform X1. (204 aa)
LOC107906690DNA polymerase epsilon subunit 3-like. (169 aa)
LOC107907069DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Unwinds duplex DNA. Component of the meiotic recombination pathway. Seems to play a role in mediating chromosome homology search, chromosome pairing and synapsis at early stages and probably chromosome crossing-over at later stages in meiosis. Probably is involved in the repair of meiotic double strand breaks (DBSs) and in homologous recombination; Belongs to the RecA family. RAD51 subfamily. (344 aa)
LOC107907498DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (525 aa)
LOC107907813Uncharacterized protein LOC107907813. (757 aa)
LOC107908075Origin of replication complex subunit 2-like. (112 aa)
LOC107908141Organ-specific protein P4-like. (110 aa)
LOC107908531DNA helicase; Belongs to the MCM family. (822 aa)
LOC107909120ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (711 aa)
LOC107907353DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (525 aa)
LOC107909874DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (326 aa)
LOC107909976TIMELESS-interacting protein-like; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (338 aa)
LOC107910013Probable DNA primase large subunit. (452 aa)
LOC107909093DNA-binding protein RHL1-like isoform X1. (457 aa)
LOC107910270DNA polymerase I isoform X1. (440 aa)
LOC107908838DNA polymerase kappa isoform X1. (689 aa)
LOC107910657DNA replication licensing factor MCM2-like. (82 aa)
LOC107910656DNA helicase; Belongs to the MCM family. (840 aa)
LOC107911002DNA cross-link repair protein SNM1-like. (587 aa)
LOC107911576Origin of replication complex subunit 5-like. (532 aa)
LOC107911799FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (540 aa)
LOC107912226DNA-binding protein BIN4-like. (386 aa)
LOC107912324DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (718 aa)
LOC107912858ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (733 aa)
LOC107911501E3 ubiquitin-protein ligase TRAIP-like. (550 aa)
LOC107911801FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (647 aa)
LOC107913171Single-stranded DNA-binding protein-like. (223 aa)
LOC107913234DNA polymerase. (1531 aa)
LOC107913539DNA helicase; Belongs to the MCM family. (839 aa)
LOC107913572Uncharacterized protein LOC107913572. (122 aa)
LOC107913609Replication factor C subunit 3-like isoform X1. (354 aa)
LOC107912765DNA ligase. (1409 aa)
LOC107914195Zinc finger protein 830-like isoform X1. (383 aa)
LOC107914740Uncharacterized protein LOC107914740 isoform X1. (274 aa)
LOC107914874DNA replication complex GINS protein PSF1. (200 aa)
LOC107913776DNA helicase; Belongs to the MCM family. (758 aa)
LOC107915273DNA polymerase eta-like. (740 aa)
LOC107914194Protein STICHEL-like isoform X1. (1315 aa)
LOC107916232DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (231 aa)
LOC107916254Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (383 aa)
LOC107916648Uncharacterized protein LOC107916648. (461 aa)
LOC107915421ATPase WRNIP1-like. (555 aa)
LOC107917216Uncharacterized protein LOC107917216. (522 aa)
LOC107917795DNA polymerase I B, chloroplastic/mitochondrial-like. (1163 aa)
LOC107916626ATP-dependent DNA helicase Q-like 5 isoform X1. (925 aa)
LOC107918200Tetratricopeptide repeat protein 38-like isoform X1. (467 aa)
LOC107918386Cell division cycle protein 123 homolog isoform X1. (322 aa)
LOC107916885Protein MCM10 homolog isoform X1. (401 aa)
LOC107917326Origin of replication complex subunit 6-like. (199 aa)
LOC107918725Protein ROOT INITIATION DEFECTIVE 3-like isoform X1. (308 aa)
LOC107918722Origin of replication complex subunit 6-like isoform X1. (287 aa)
LOC107918535Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (414 aa)
LOC107920678Uncharacterized protein YpgQ-like isoform X1. (239 aa)
LOC107920789DNA helicase; Belongs to the MCM family. (839 aa)
LOC107919835ATP-dependent DNA helicase Q-like 4A isoform X1. (1203 aa)
LOC107921247Protein MCM10 homolog. (401 aa)
LOC107921785E3 ubiquitin-protein ligase UPL3-like isoform X1. (1907 aa)
LOC107920673DNA polymerase. (1097 aa)
LOC107920927Uncharacterized protein LOC107920927 isoform X1. (336 aa)
LOC107921384Organ-specific protein P4-like. (108 aa)
LOC107922502ATP-dependent DNA helicase Q-like 5 isoform X1. (945 aa)
LOC107923010Protein POLYCHOME-like. (257 aa)
LOC107923086E3 ubiquitin-protein ligase TRAIP-like isoform X1. (550 aa)
LOC107923182Origin of replication complex subunit 5-like. (525 aa)
LOC107923222E3 ubiquitin-protein ligase UPL3-like. (1903 aa)
LOC107922452Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (807 aa)
LOC107922612Flap endonuclease 1-like. (74 aa)
LOC107922471DNA-binding protein BIN4-like. (387 aa)
LOC107922673Origin of replication complex subunit 2-like. (99 aa)
LOC107922782CDT1-like protein a, chloroplastic. (609 aa)
LOC107924104CDT1-like protein a, chloroplastic. (647 aa)
LOC107924261FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (647 aa)
LOC107924100Regulator of telomere elongation helicase 1-like isoform X1. (1024 aa)
LOC107925060Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (807 aa)
LOC107925199Protein STICHEL-like 3 isoform X1. (1184 aa)
LOC107925577Uncharacterized protein LOC107925577. (1199 aa)
LOC107925687Protein downstream neighbor of Son-like. (621 aa)
LOC107924650DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (718 aa)
LOC107925722Protein POLYCHOME-like. (257 aa)
LOC107925403Organ-specific protein P4-like. (108 aa)
LOC107925704Cell division control protein 45 homolog. (595 aa)
LOC107927137DNA ligase. (796 aa)
LOC107927203Uncharacterized protein LOC107927203. (161 aa)
LOC107927240FACT complex subunit SPT16-like. (1065 aa)
LOC107927582Replication factor C subunit 1. (992 aa)
LOC107926968Cell division cycle protein 123 homolog. (334 aa)
LOC107928309Origin of replication complex subunit 6-like. (197 aa)
LOC107927308ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (882 aa)
LOC107928346DNA-binding protein RHL1-like isoform X1. (442 aa)
LOC107927199ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (611 aa)
LOC107928765Cell division control protein; Belongs to the CDC6/cdc18 family. (509 aa)
LOC107927807Ribonucleoside-diphosphate reductase small chain A. (348 aa)
LOC107929188Replication factor C subunit 2. (332 aa)
LOC107930034Cell division cycle protein 123 homolog. (334 aa)
LOC107928922E3 ubiquitin-protein ligase UPL3-like. (1889 aa)
LOC107930162Uncharacterized protein LOC107930162. (994 aa)
LOC107931409Protein RTF2 homolog. (340 aa)
LOC107932759DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (897 aa)
LOC107932837E3 ubiquitin-protein ligase RNF181-like. (139 aa)
LOC107931848Sister chromatid cohesion protein DCC1-like. (386 aa)
LOC107932814Origin of replication complex subunit 2-like. (99 aa)
LOC107932564E3 ubiquitin-protein ligase UPL3-like. (1905 aa)
LOC107933321Protein OSB3, chloroplastic/mitochondrial-like. (330 aa)
LOC107934367DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (209 aa)
LOC107934411DNA/RNA-binding protein KIN17. (394 aa)
LOC107935553Origin of replication complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (421 aa)
LOC107935704Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (266 aa)
LOC107934693Uncharacterized protein LOC107934693. (535 aa)
LOC107936368Sister chromatid cohesion protein DCC1-like isoform X1. (385 aa)
LOC107936538Uncharacterized protein LOC107936538. (760 aa)
LOC107935512Origin of replication complex subunit 4-like. (167 aa)
LOC107936712CDT1-like protein a, chloroplastic. (601 aa)
LOC107936782Replication protein A 14 kDa subunit B-like. (106 aa)
LOC107935920DNA helicase; Belongs to the MCM family. (758 aa)
LOC107936991E3 ubiquitin-protein ligase UPL3-like isoform X1. (1887 aa)
LOC107937263DNA ligase 1-like. (196 aa)
LOC107937350Regulator of telomere elongation helicase 1-like isoform X1. (1012 aa)
LOC107937412Replication factor C subunit 3-like isoform X1. (354 aa)
LOC107937909Replication protein A 32 kDa subunit A-like. (286 aa)
LOC107938642DNA polymerase I B, chloroplastic/mitochondrial-like. (1136 aa)
LOC107938861Organ-specific protein P4-like. (110 aa)
LOC107937850DNA polymerase delta subunit 4-like isoform X1. (116 aa)
LOC107937970Helicase and polymerase-containing protein TEBICHI-like isoform X1. (2162 aa)
LOC107937982DNA helicase; Belongs to the MCM family. (734 aa)
LOC107939484E3 ubiquitin-protein ligase RNF181-like. (139 aa)
LOC107938485DNA replication licensing factor MCM6-like; Belongs to the MCM family. (484 aa)
LOC107938484DNA replication licensing factor MCM6-like. (270 aa)
LOC107940023Origin of replication complex subunit 3-like isoform X1. (724 aa)
LOC107940281DNA ligase. (1168 aa)
LOC107940679Protein OSB1, mitochondrial. (278 aa)
LOC107940857DNA replication licensing factor MCM5-like. (83 aa)
LOC107940962Probable DNA replication complex GINS protein PSF1. (151 aa)
LOC107941224Multifunctional non-homologous end joining protein LigD-like. (850 aa)
LOC107941239Protein ROOT INITIATION DEFECTIVE 3-like isoform X1. (474 aa)
LOC107941566Protein ROOT INITIATION DEFECTIVE 3-like. (444 aa)
LOC107940484Mini-chromosome maintenance complex-binding protein-like isoform X1. (593 aa)
LOC107940558Replication factor C subunit 5. (363 aa)
LOC107942638DNA helicase; Belongs to the MCM family. (790 aa)
LOC107941655Protein OSB2, chloroplastic-like. (296 aa)
LOC107943530DNA-directed primase/polymerase protein-like. (613 aa)
LOC107943553Ribonucleoside-diphosphate reductase small chain A-like. (185 aa)
LOC107942736Replication protein A 32 kDa subunit B-like isoform X1. (283 aa)
LOC107943472Single-stranded DNA-binding protein-like. (142 aa)
LOC107944775ATP-dependent DNA helicase; Belongs to the helicase family. (751 aa)
LOC107943937Centromere protein S-like. (102 aa)
LOC107943981DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (1324 aa)
LOC107945355DNA topoisomerase 6 subunit B; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP; Belongs to the TOP6B family. (669 aa)
LOC107944611Protein ROOT INITIATION DEFECTIVE 3-like. (444 aa)
LOC107946806Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (858 aa)
LOC107947091DNA primase; Belongs to the eukaryotic-type primase small subunit family. (452 aa)
LOC107947324DNA-directed primase/polymerase protein-like isoform X1. (613 aa)
LOC107946589Centromere protein X. (108 aa)
LOC107948266DNA ligase 1-like isoform X1. (180 aa)
LOC107947115DNA primase; Belongs to the eukaryotic-type primase small subunit family. (452 aa)
LOC107948426DNA polymerase delta small subunit-like. (439 aa)
LOC107948418Protein TONSOKU-like isoform X1. (1351 aa)
LOC107948535DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (526 aa)
LOC107947368Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (861 aa)
LOC107947329Protein timeless homolog isoform X1. (1201 aa)
LOC107948602LOW QUALITY PROTEIN: DNA replication ATP-dependent helicase/nuclease DNA2-like. (1351 aa)
LOC107948791Nucleolar and coiled-body phosphoprotein 1-like. (529 aa)
LOC107949298Replication factor C subunit 3-like. (98 aa)
LOC107948805Uncharacterized protein LOC107948805 isoform X1. (1370 aa)
LOC107949761WD repeat and HMG-box DNA-binding protein 1-like. (975 aa)
LOC107949785Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (626 aa)
LOC107949799DNA annealing helicase and endonuclease ZRANB3-like isoform X1. (1287 aa)
LOC107950350Uncharacterized protein LOC107950350 isoform X1. (194 aa)
LOC107950364Cell division control protein; Belongs to the CDC6/cdc18 family. (509 aa)
LOC107949689Flap endonuclease 1-like. (86 aa)
LOC107950594Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (807 aa)
LOC107950214Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (266 aa)
LOC107963759Replication factor C subunit 2-like. (332 aa)
LOC107963291RING-H2 zinc finger protein RHA1a-like. (114 aa)
LOC107962295SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1. (688 aa)
LOC107961644DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Unwinds duplex DNA. Component of the meiotic recombination pathway. Seems to play a role in mediating chromosome homology search, chromosome pairing and synapsis at early stages and probably chromosome crossing-over at later stages in meiosis. Probably is involved in the repair of meiotic double strand breaks (DBSs) and in homologous recombination; Belongs to the RecA family. RAD51 subfamily. (343 aa)
LOC107960241Protein STICHEL-like 3. (1149 aa)
LOC107960652DNA polymerase eta-like. (740 aa)
LOC107959344Mini-chromosome maintenance complex-binding protein-like. (593 aa)
LOC107959946Origin of replication complex subunit 2-like isoform X1. (105 aa)
LOC107959376DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2204 aa)
LOC107959354DNA polymerase epsilon subunit 3-like. (211 aa)
LOC107956541Uncharacterized protein LOC107956541. (763 aa)
LOC1079574815'-3' exonuclease-like. (380 aa)
LOC107955444CDT1-like protein a, chloroplastic. (601 aa)
LOC107955654Origin of replication complex subunit 6-like. (163 aa)
LOC107955470Protein OSB2, chloroplastic-like. (295 aa)
LOC107953799Protein RTF2 homolog. (156 aa)
LOC107953585Centromere protein S. (141 aa)
LOC107953645Single-stranded DNA-binding protein-like. (223 aa)
LOC107953562Protein STICHEL-like 2. (1006 aa)
LOC107952113DNA topoisomerase 2-binding protein 1-A-like. (985 aa)
LOC107951878Origin of replication complex subunit 3-like isoform X1. (724 aa)
LOC107951716Replication protein A 14 kDa subunit B-like. (106 aa)
Your Current Organism:
Gossypium hirsutum
NCBI taxonomy Id: 3635
Other names: American cotton, American upland cotton, G. hirsutum, Gossypium hirsutum L., Gossypium hirsutum subsp. mexicanum, Gossypium hirsutum subsp. mexicanum (Tod.) Mauer, Gossypium lanceolatum, Gossypium lanceolatum Tod., Gossypium purpurascens, Gossypium purpurascens Poir., cotton
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