(10 nodes) Peptidyl-diphthamide metabolic process network (Theobroma cacao)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	TCM_001431	Ribosomal protein S5/Elongation factor G/III/V family protein. (1027 aa)
	TCM_006443	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (458 aa)
	TCM_006287	CSL zinc finger domain-containing protein isoform 1. (82 aa)
	TCM_023045	Uncharacterized protein. (243 aa)
	TCM_026179	Endoribonucleases isoform 4. (632 aa)
	TCM_012451	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. (833 aa)
	TCM_012103	Transducin/WD40 repeat-like superfamily protein isoform 1. (350 aa)
	TCM_016040	Elongation factor G, chloroplastic; Chloroplast-localized elongation factor EF-G involved in protein synthesis in plastids. Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl- tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. (783 aa)
	TCM_041214	Uncharacterized protein. (247 aa)
	TCM_040866	Tetrapyrrole (Corrin/Porphyrin) Methylases isoform 1. (285 aa)

Your Current Organism:

Theobroma cacao

NCBI taxonomy Id: 3641
Other names: T. cacao, Theobroma cacao L., cacao, chocolate, cocoa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TCM_001431	TCM_006287	A0A061DKB2	A0A061E4P2	Ribosomal protein S5/Elongation factor G/III/V family protein.	CSL zinc finger domain-containing protein isoform 1.	0.481
TCM_001431	TCM_006443	A0A061DKB2	A0A061DX88	Ribosomal protein S5/Elongation factor G/III/V family protein.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	0.822
TCM_001431	TCM_012103	A0A061DKB2	A0A061G165	Ribosomal protein S5/Elongation factor G/III/V family protein.	Transducin/WD40 repeat-like superfamily protein isoform 1.	0.609
TCM_001431	TCM_012451	A0A061DKB2	A0A061FVK3	Ribosomal protein S5/Elongation factor G/III/V family protein.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2.	0.822
TCM_001431	TCM_023045	A0A061DKB2	A0A061EVR7	Ribosomal protein S5/Elongation factor G/III/V family protein.	Uncharacterized protein.	0.481
TCM_001431	TCM_026179	A0A061DKB2	A0A061F0M1	Ribosomal protein S5/Elongation factor G/III/V family protein.	Endoribonucleases isoform 4.	0.956
TCM_001431	TCM_040866	A0A061DKB2	A0A061GZD5	Ribosomal protein S5/Elongation factor G/III/V family protein.	Tetrapyrrole (Corrin/Porphyrin) Methylases isoform 1.	0.762
TCM_001431	TCM_041214	A0A061DKB2	A0A061GVS7	Ribosomal protein S5/Elongation factor G/III/V family protein.	Uncharacterized protein.	0.481
TCM_006287	TCM_001431	A0A061E4P2	A0A061DKB2	CSL zinc finger domain-containing protein isoform 1.	Ribosomal protein S5/Elongation factor G/III/V family protein.	0.481
TCM_006287	TCM_006443	A0A061E4P2	A0A061DX88	CSL zinc finger domain-containing protein isoform 1.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	0.812
TCM_006287	TCM_012451	A0A061E4P2	A0A061FVK3	CSL zinc finger domain-containing protein isoform 1.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2.	0.812
TCM_006287	TCM_016040	A0A061E4P2	A0A061G5G1	CSL zinc finger domain-containing protein isoform 1.	Elongation factor G, chloroplastic; Chloroplast-localized elongation factor EF-G involved in protein synthesis in plastids. Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl- tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.	0.481
TCM_006287	TCM_026179	A0A061E4P2	A0A061F0M1	CSL zinc finger domain-containing protein isoform 1.	Endoribonucleases isoform 4.	0.611
TCM_006443	TCM_001431	A0A061DX88	A0A061DKB2	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	Ribosomal protein S5/Elongation factor G/III/V family protein.	0.822
TCM_006443	TCM_006287	A0A061DX88	A0A061E4P2	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	CSL zinc finger domain-containing protein isoform 1.	0.812
TCM_006443	TCM_012103	A0A061DX88	A0A061G165	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	Transducin/WD40 repeat-like superfamily protein isoform 1.	0.517
TCM_006443	TCM_016040	A0A061DX88	A0A061G5G1	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	Elongation factor G, chloroplastic; Chloroplast-localized elongation factor EF-G involved in protein synthesis in plastids. Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl- tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.	0.822
TCM_006443	TCM_023045	A0A061DX88	A0A061EVR7	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	Uncharacterized protein.	0.812
TCM_006443	TCM_026179	A0A061DX88	A0A061F0M1	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	Endoribonucleases isoform 4.	0.654
TCM_006443	TCM_040866	A0A061DX88	A0A061GZD5	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	Tetrapyrrole (Corrin/Porphyrin) Methylases isoform 1.	0.822