48 items (Theobroma cacao) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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	TCM_001405	Amino acid kinase family protein. (340 aa)
	TCM_001302	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (807 aa)
	TCM_001359	Carbamoyl phosphate synthetase A isoform 2. (428 aa)
	TCM_001713	Pyrimidin 4. (346 aa)
	TCM_002307	Thymidine kinase. (227 aa)
	TCM_002688	RS21-C6, EAR, NTP pyrophosphohydrolase MazG catalytic core, putative. (180 aa)
	TCM_004769	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (562 aa)
	TCM_005955	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (598 aa)
	TCM_006844	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. (529 aa)
	TCM_005727	Nucleoside diphosphate kinase. (148 aa)
	TCM_007373	Beta-ureidopropionase. (416 aa)
	TCM_007692	Dihydroorotate dehydrogenase, putative. (322 aa)
	TCM_011708	GDA1/CD39 nucleoside phosphatase family protein, putative isoform 1; Belongs to the GDA1/CD39 NTPase family. (546 aa)
	TCM_011378	Phosphoribulokinase / Uridine kinase family isoform 1. (658 aa)
	TCM_017168	Uridine kinase; Belongs to the uridine kinase family. (466 aa)
	TCM_019290	P-loop containing nucleoside triphosphate hydrolases superfamily protein. (264 aa)
	TCM_017004	Uridine kinase; Belongs to the uridine kinase family. (453 aa)
	TCM_017203	Ferritin/ribonucleotide reductase-like family protein. (329 aa)
	TCM_020615	Survival protein SurE-like phosphatase/nucleotidase. (309 aa)
	TCM_020614	Survival protein SurE-like phosphatase/nucleotidase, putative isoform 2. (317 aa)
	TCM_020926	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (120 aa)
	TCM_020157	RS21-C6, EAR, NTP pyrophosphohydrolase MazG catalytic core, putative isoform 1. (157 aa)
	TCM_020494	Ribonucleoside-diphosphate reductase small chain A isoform 1. (470 aa)
	TCM_022528	Uridine-ribohydrolase 1 isoform 1. (344 aa)
	TCM_021854	Uracil phosphoribosyltransferase. (345 aa)
	TCM_030814	Pyrimidine b; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (401 aa)
	TCM_031360	Uridine 5'-monophosphate synthase / UMP synthase (PYRE-F) (UMPS) isoform 1. (484 aa)
	TCM_031657	Carbamoyl phosphate synthetase B. (1208 aa)
	TCM_026034	Apyrase 1; Belongs to the GDA1/CD39 NTPase family. (557 aa)
	TCM_030572	Uridine kinase; Belongs to the uridine kinase family. (478 aa)
	TCM_033690	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (603 aa)
	TCM_034021	Dutp-pyrophosphatase-like 1. (199 aa)
	TCM_034096	Thymidylate synthase 1, putative; Belongs to the dihydrofolate reductase family. (290 aa)
	TCM_042355	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (216 aa)
	TCM_043327	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (209 aa)
	TCM_012994	Pyrimidine 1 isoform 1. (426 aa)
	TCM_014126	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (126 aa)
	TCM_014573	Nucleoside diphosphate kinase. (237 aa)
	TCM_014447	Phosphoribulokinase / Uridine kinase family isoform 1. (660 aa)
	TCM_014822	Nucleoside diphosphate kinase. (148 aa)
	TCM_016472	Pleckstrin (PH) domain-containing protein isoform 1. (245 aa)
	TCM_030387	Thymidine kinase. (205 aa)
	TCM_029062	Acid phosphatase. (388 aa)
	TCM_037673	Alkaline-phosphatase-like family protein isoform 1. (492 aa)
	TCM_037637	Acid phosphatase, putative isoform 1. (389 aa)
	TCM_037679	Cytidine deaminase. (304 aa)
	TCM_040834	Indigoidine synthase A family protein isoform 1. (334 aa)
	TCM_040900	Pyrimidine 2 isoform 1. (534 aa)

Your Current Organism:

Theobroma cacao

NCBI taxonomy Id: 3641
Other names: T. cacao, Theobroma cacao L., cacao, chocolate, cocoa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TCM_001302	TCM_001405	A0A061DJ55	A0A061DIT8	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Amino acid kinase family protein.	0.622
TCM_001302	TCM_002307	A0A061DJ55	A0A061DMW8	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Thymidine kinase.	0.463
TCM_001302	TCM_002688	A0A061DJ55	A0A061DNX6	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	RS21-C6, EAR, NTP pyrophosphohydrolase MazG catalytic core, putative.	0.900
TCM_001302	TCM_005727	A0A061DJ55	A0A061E2I2	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Nucleoside diphosphate kinase.	0.943
TCM_001302	TCM_006844	A0A061DJ55	A0A061E0T8	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	0.887
TCM_001302	TCM_011708	A0A061DJ55	A0A061EAG1	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	GDA1/CD39 nucleoside phosphatase family protein, putative isoform 1; Belongs to the GDA1/CD39 NTPase family.	0.916
TCM_001302	TCM_014126	A0A061DJ55	A0A061FYJ4	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	0.900
TCM_001302	TCM_014573	A0A061DJ55	A0A061FYQ0	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Nucleoside diphosphate kinase.	0.943
TCM_001302	TCM_014822	A0A061DJ55	A0A061FZ11	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Nucleoside diphosphate kinase.	0.943
TCM_001302	TCM_016472	A0A061DJ55	A0A061G775	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Pleckstrin (PH) domain-containing protein isoform 1.	0.943
TCM_001302	TCM_017203	A0A061DJ55	A0A061EKJ4	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Ferritin/ribonucleotide reductase-like family protein.	0.996
TCM_001302	TCM_019290	A0A061DJ55	A0A061EG90	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	P-loop containing nucleoside triphosphate hydrolases superfamily protein.	0.961
TCM_001302	TCM_020157	A0A061DJ55	A0A061ERV9	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	RS21-C6, EAR, NTP pyrophosphohydrolase MazG catalytic core, putative isoform 1.	0.900
TCM_001302	TCM_020494	A0A061DJ55	A0A061ET75	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Ribonucleoside-diphosphate reductase small chain A isoform 1.	0.996
TCM_001302	TCM_020926	A0A061DJ55	A0A061ENZ8	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	0.902
TCM_001302	TCM_021854	A0A061DJ55	A0A061EYQ6	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Uracil phosphoribosyltransferase.	0.402
TCM_001302	TCM_026034	A0A061DJ55	A0A061F8C2	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Apyrase 1; Belongs to the GDA1/CD39 NTPase family.	0.908
TCM_001302	TCM_030387	A0A061DJ55	A0A061GGB4	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Thymidine kinase.	0.463
TCM_001302	TCM_031360	A0A061DJ55	A0A061F719	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Uridine 5'-monophosphate synthase / UMP synthase (PYRE-F) (UMPS) isoform 1.	0.419
TCM_001302	TCM_034021	A0A061DJ55	A0A061FJT4	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Dutp-pyrophosphatase-like 1.	0.753