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murF | Candidate UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (497 aa) | ||||
Rta_34230 | Candidate asparagine synthetase (glutamine-hydrolyzing). (595 aa) | ||||
Rta_34220 | Acetyltransferases-like protein. (589 aa) | ||||
purM | Candidate phosphoribosylformylglycinamidine cyclo-ligase(Phosphoribosyl-aminoimidazole synthetase). (344 aa) | ||||
gshA | Candidate gamma-glutamylcysteine synthetase (glutamate--cysteine ligase); Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. (517 aa) | ||||
pncB | Candidate nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (400 aa) | ||||
Rta_26685 | Conserved hypothetical protein. (149 aa) | ||||
pyrG | Candidate CTP synthase (UTP--ammonia ligase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa) | ||||
coaBC | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (409 aa) | ||||
Rta_25500 | Conserved hypothetical protein. (861 aa) | ||||
Rta_25360 | Conserved hypothetical protein. (498 aa) | ||||
nadE | Candidate NAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (538 aa) | ||||
purD | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. (426 aa) | ||||
purL | Candidate phosphoribosylformylglycinamidine synthase (FGAM synthase); Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1336 aa) | ||||
guaA | Candidate GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (537 aa) | ||||
purA | Candidate adenylosuccinate synthetase (IMP--aspartate ligase); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (443 aa) | ||||
Rta_17990 | Glutamine synthetase (Glutamate--ammonia ligase)-like protein. (493 aa) | ||||
carB | Candidate carbamoyl-phosphate synthase large chain (Carbamoyl-phosphate synthase (ammonia)); Belongs to the CarB family. (1084 aa) | ||||
carA | Candidate carbamoyl-phosphate synthase small chain (Carbamoyl-phosphate synthase (glutamine-hydrolyzing)); Belongs to the CarA family. (387 aa) | ||||
Rta_16380 | Obyrinic acid A,C-diamide synthase-like protein. (441 aa) | ||||
tilS | Candidate tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (328 aa) | ||||
glnA | Candidate glutamine synthetase (Glutamate--ammonia ligase). (472 aa) | ||||
folC | Tetrahydrofolylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (432 aa) | ||||
argG | Candidate argininosuccinate synthase (Citrulline--aspartate ligase); Belongs to the argininosuccinate synthase family. Type 2 subfamily. (448 aa) | ||||
accC | Candidate Biotin carboxylase (subunit of acetyl-CoA carboxylase); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) | ||||
mpl | UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (457 aa) | ||||
ddlA | Candidate D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (323 aa) | ||||
murC | Candidate UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (470 aa) | ||||
murD | Candidate UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase (D-glutamic acid adding enzyme); Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (510 aa) | ||||
Rta_35950 | Candidate carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (382 aa) | ||||
murE | Candidate UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (494 aa) | ||||
Rta_07440 | Conserved hypothetical protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (194 aa) | ||||
gatB | Candidate Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (482 aa) | ||||
gatA | Candidate Glutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (487 aa) | ||||
gatC | Candidate Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (115 aa) | ||||
gshB | Candidate glutathione synthetase (glutathione synthase); Belongs to the prokaryotic GSH synthase family. (319 aa) | ||||
queC | Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (205 aa) | ||||
Rta_37590 | Glutamine synthetase (Glutamate--ammonia ligase)-like protein. (455 aa) | ||||
birA | Candidate bifunctional protein (BirA) : transcriptional regulator (Biotin operon repressor), BirA family; Biotin-- [acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase). (260 aa) | ||||
purC | Candidate phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (302 aa) | ||||
purK | Candidate phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (391 aa) |