STRINGSTRING
glcE glcE gclF gclF Rta_02350 Rta_02350 glcB glcB Rta_05680 Rta_05680 ttuC ttuC Rta_06380 Rta_06380 Rta_06660 Rta_06660 Rta_10430 Rta_10430 lpd lpd eda eda Rta_12730 Rta_12730 glnA glnA gcvP gcvP gcvH gcvH gcvT gcvT glyA glyA acsA acsA Rta_16260 Rta_16260 Rta_17990 Rta_17990 Rta_18100 Rta_18100 phbB phbB Rta_18230 Rta_18230 Rta_18250 Rta_18250 accA-2 accA-2 Rta_18580 Rta_18580 Rta_18700 Rta_18700 Rta_18810 Rta_18810 Rta_20040 Rta_20040 katE katE aceA aceA Rta_24470 Rta_24470 tkrA-2 tkrA-2 Rta_27120 Rta_27120 kynB kynB acnA acnA acnB acnB mdh mdh gltA gltA Rta_28620 Rta_28620 Rta_30045 Rta_30045 Rta_30480 Rta_30480 fdhB fdhB fdhF fdhF Rta_30590 Rta_30590 Rta_30600 Rta_30600 ttuD ttuD katE-2 katE-2 gph-2 gph-2 katE-3 katE-3 purU purU glcD glcD Rta_37590 Rta_37590 Rta_38110 Rta_38110
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glcECandidate Glycolate oxidase subunit. (364 aa)
gclFCandidate Glycolate oxidase iron-sulfur subunit. (409 aa)
Rta_02350Candidate Esterase/lipase. (285 aa)
glcBCandidate Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (732 aa)
Rta_05680Acetyl-CoA C-acetyltransferase-like protein; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
ttuCCandidate Tartrate dehydrogenase. (359 aa)
Rta_06380Hydroxyperoxidase II-like protein; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. (332 aa)
Rta_06660D-3-phosphoglycerate dehydrogenase (phosphoglycerate dehydrogenase)-like protein. (306 aa)
Rta_10430Acetyl-CoA synthase (Acetate thiokinase). (603 aa)
lpdDihydrolipoamide dehydrogenase. (464 aa)
eda2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase; Candidate bifunctional protein: 4-hydroxy-2-oxoglutarate aldolase (2-keto-4-hydroxyglutarate aldolase); 2- dehydro-3-deoxyphosphogluconate aldolase (Phospho-2- dehydro-3-deoxygluconate aldolase). (214 aa)
Rta_12730Conserved hypothetical protein. (283 aa)
glnACandidate glutamine synthetase (Glutamate--ammonia ligase). (472 aa)
gcvPGlycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (960 aa)
gcvHCandidate glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (125 aa)
gcvTCandidate aminomethyltransferase (Glycine cleavage system T protein). (378 aa)
glyACandidate serine hydroxymethyltransferase (Serine methylase); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (414 aa)
acsACandidate acetyl-coenzyme A synthetase(Acetate--CoA ligase); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (661 aa)
Rta_16260Candidate serine--glyoxylate aminotransferase (Serine--glyoxylate transaminase). (395 aa)
Rta_17990Glutamine synthetase (Glutamate--ammonia ligase)-like protein. (493 aa)
Rta_18100Acetyl-CoA C-acetyltransferase-like protein; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
phbBCandidate acetoacetyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa)
Rta_18230Candidate methylmalonyl-CoA mutase. (717 aa)
Rta_18250Candidate propionyl-CoA carboxylase. (510 aa)
accA-2Candidate Acetyl or propionyl-CoA carboxylase subunit. (682 aa)
Rta_18580Formimidoylglutamase. (283 aa)
Rta_18700Candidate dihydrolipoyl dehydrogenase (Dihydrolipoamide dehydrogenase). (598 aa)
Rta_18810Dihydrolipoamide dehydrogenase. (476 aa)
Rta_200403-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
katECandidate hydroperoxidase II. (817 aa)
aceAIsocitratase. (441 aa)
Rta_24470Candidate tartrate dehydrogenase. (361 aa)
tkrA-2Candidate 2-ketogluconate reductase (Gluconate 2-dehydrogenase); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (328 aa)
Rta_27120TsaR. (309 aa)
kynBConserved hypothetical protein; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. (198 aa)
acnACandidate aconitase (aconitate hydratase). (952 aa)
acnBAconitase 2; Belongs to the aconitase/IPM isomerase family. (861 aa)
mdhCandidate malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa)
gltACandidate citrate synthase; Belongs to the citrate synthase family. (436 aa)
Rta_28620Phosphoglycolate phosphatase-like protein. (219 aa)
Rta_30045Conserved hypothetical protein. (187 aa)
Rta_30480Candidate formate dehydrogenase subunit C precursor. (406 aa)
fdhBCandidate formate dehydrogenase iron-sulfur subunit. (205 aa)
fdhFCandidate formate dehydrogenase large subunit (Formate-hydrogen-lyase-linked, selenocysteine-containing polypeptide); Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (990 aa)
Rta_30590Formate dehydrogenase (Formate-hydrogen-lyase-linked, selenocysteine-containing polypeptide)-like protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (944 aa)
Rta_30600Formate dehydrogenase beta subunit; NADH:ubiquinone oxidoreductase subunit 2 or 24 kDa subunit and subunit 1 or 51 kDa subunit fusion, chain E and chain F fusion-like protein. (569 aa)
ttuDCandidate hydroxypyruvate reductase. (451 aa)
katE-2Candidate hydroperoxidase II. (540 aa)
gph-2Candidate phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (237 aa)
katE-3Candidate hydroperoxidase II; Serves to protect cells from the toxic effects of hydrogen peroxide. (718 aa)
purUCandidate formyltetrahydrofolate deformylase (Formyl-FH(4) hydrolase); Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (282 aa)
glcDCandidate glycolate oxidase subunit glcD. (475 aa)
Rta_37590Glutamine synthetase (Glutamate--ammonia ligase)-like protein. (455 aa)
Rta_38110Phosphoglycolate phosphatase-like protein. (247 aa)
Your Current Organism:
Ramlibacter tataouinensis
NCBI taxonomy Id: 365046
Other names: Acidivorax sp. TTB310, Acidovorax sp. TTB310, R. tataouinensis TTB310, Ramlibacter tataouinensis TTB310, Ramlibacter tataouinensis str. TTB310, Ramlibacter tataouinensis strain TTB310
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.