STRINGSTRING
SIR22733.1 SIR22733.1 SIR32089.1 SIR32089.1 SIR31513.1 SIR31513.1 SIR28445.1 SIR28445.1 clpB clpB rep rep recB recB ychF ychF ftsH ftsH SIQ45017.1 SIQ45017.1 SIQ46420.1 SIQ46420.1 SIQ50042.1 SIQ50042.1 SIQ53314.1 SIQ53314.1 SIQ56997.1 SIQ56997.1 recG recG srmB srmB SIQ81493.1 SIQ81493.1 mutL mutL SIQ88155.1 SIQ88155.1 SIQ88570.1 SIQ88570.1 SIQ86065.1 SIQ86065.1 clpX clpX lon lon rhlB rhlB SIQ97167.1 SIQ97167.1 hslU hslU SIR03409.1 SIR03409.1 uvrA uvrA SIR08952.1 SIR08952.1 SIR09106.1 SIR09106.1 htpG htpG smc smc SIR15325.1 SIR15325.1 SIR15399.1 SIR15399.1 SIR17137.1 SIR17137.1 hscA hscA ruvA ruvA ruvB ruvB uvrB uvrB SIR23501.1 SIR23501.1 SIR45232.1 SIR45232.1 zapE zapE SIR39213.1 SIR39213.1 SIR36154.1 SIR36154.1 SIR35507.1 SIR35507.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SIR22733.1AAA ATPase domain-containing protein. (395 aa)
SIR32089.1Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (468 aa)
SIR31513.1Cell division protein ZapE. (409 aa)
SIR28445.1Hypothetical protein. (38 aa)
clpBATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (857 aa)
repATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (670 aa)
recBDNA helicase/exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombi [...] (1256 aa)
ychFHypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (363 aa)
ftsHMembrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (652 aa)
SIQ45017.1ATP-binding cassette protein, ChvD family. (555 aa)
SIQ46420.1Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. (433 aa)
SIQ50042.1Flagellum-specific ATP synthase. (445 aa)
SIQ53314.1Cu+-exporting ATPase. (744 aa)
SIQ56997.1Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. (472 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (691 aa)
srmBATP-dependent RNA helicase SrmB; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (420 aa)
SIQ81493.1Protein of unknown function. (1224 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (637 aa)
SIQ88155.1Protein of unknown function. (260 aa)
SIQ88570.1Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. (451 aa)
SIQ86065.1MoxR-like ATPase. (318 aa)
clpXATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (425 aa)
lonATP-dependent proteinase. Serine peptidase. MEROPS family S16; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (785 aa)
rhlBATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (438 aa)
SIQ97167.1Flagellum-specific ATP synthase. (444 aa)
hslUATP-dependent HslUV protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (442 aa)
SIR03409.1ATP-dependent DNA helicase UvrD. (722 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (960 aa)
SIR08952.1ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. (755 aa)
SIR09106.1ATP-binding protein involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (376 aa)
htpGMolecular chaperone HtpG; Molecular chaperone. Has ATPase activity. (637 aa)
smcCondensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1137 aa)
SIR15325.1Superfamily I DNA and RNA helicases. (560 aa)
SIR15399.1Predicted ATPase. (370 aa)
SIR17137.1Septum site-determining protein MinD. (269 aa)
hscAChaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. (620 aa)
ruvAHolliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (205 aa)
ruvBHolliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (334 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (668 aa)
SIR23501.1MoxR-like ATPase. (303 aa)
SIR45232.1ATP-binding cassette, subfamily F, uup. (641 aa)
zapECell division protein ZapE; Reduces the stability of FtsZ polymers in the presence of ATP. (370 aa)
SIR39213.1Nitric oxide reductase NorQ protein. (261 aa)
SIR36154.1Recombination protein MgsA. (443 aa)
SIR35507.1Cu2+-exporting ATPase. (799 aa)
Your Current Organism:
Shewanella morhuae
NCBI taxonomy Id: 365591
Other names: NBRC 100978, S. morhuae, Shewanella morhuae Satomi et al. 2006 emend. Thorell et al. 2019, strain U1417
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