(49 nodes) RNA Polymerase II Promoter Escape network (Cucumis sativus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Csa_7G390040	Helicase ATP-binding domain-containing protein. (758 aa)
	Csa_6G014650	RPOL4c domain-containing protein. (138 aa)
	Csa_7G374590	Uncharacterized protein. (207 aa)
	Csa_7G426580	RNA_pol_L_2 domain-containing protein. (162 aa)
	Csa_6G014610	Uncharacterized protein. (369 aa)
	Csa_6G188660	Uncharacterized protein. (536 aa)
	Csa_6G510870	RPOL4c domain-containing protein. (220 aa)
	Csa_6G490020	CYCLIN domain-containing protein; Belongs to the cyclin family. (332 aa)
	Csa_6G517270	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (451 aa)
	Csa_5G152930	Uncharacterized protein. (821 aa)
	Csa_6G502590	Uncharacterized protein. (443 aa)
	Csa_5G435050	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1963 aa)
	Csa_6G517340	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1248 aa)
	Csa_5G169080	General transcription factor IIH subunit. (423 aa)
	Csa_5G312340	Uncharacterized protein. (176 aa)
	Csa_5G600940	Uncharacterized protein. (71 aa)
	Csa_5G492360	TFIIF_beta domain-containing protein. (190 aa)
	Csa_5G492870	Uncharacterized protein. (97 aa)
	Csa_4G009360	RTR1-type domain-containing protein. (662 aa)
	Csa_4G049080	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (277 aa)
	Csa_5G643990	RPOL4c domain-containing protein. (121 aa)
	Csa_4G098200	Uncharacterized protein. (303 aa)
	Csa_4G338430	Uncharacterized protein. (303 aa)
	Csa_4G415910	TFIIB-type domain-containing protein. (312 aa)
	Csa_4G338420	BSD domain-containing protein. (388 aa)
	Csa_3G039340	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1483 aa)
	Csa_4G651950	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1197 aa)
	Csa_3G036500	Uncharacterized protein. (70 aa)
	Csa_3G143540	Uncharacterized protein. (190 aa)
	Csa_3G002510	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1867 aa)
	Csa_3G129690	Uncharacterized protein. (445 aa)
	Csa_3G166240	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (114 aa)
	Csa_3G624050	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (538 aa)
	Csa_3G690810	RNA_pol_L_2 domain-containing protein. (116 aa)
	Csa_3G822200	Uncharacterized protein. (227 aa)
	Csa_3G815480	Uncharacterized protein. (54 aa)
	Csa_3G877600	Uncharacterized protein. (142 aa)
	Csa_2G093850	RPOLD domain-containing protein. (320 aa)
	Csa_2G193330	Uncharacterized protein. (175 aa)
	Csa_2G401990	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (106 aa)
	Csa_2G072450	Uncharacterized protein. (295 aa)
	Csa_1G024870	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (418 aa)
	Csa_2G401490	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (106 aa)
	Csa_1G043180	Uncharacterized protein. (51 aa)
	Csa_2G363560	Uncharacterized protein. (260 aa)
	Csa_1G020880	HTH TFE/IIEalpha-type domain-containing protein. (476 aa)
	Csa_1G257890	Uncharacterized protein. (894 aa)
	Csa_1G257900	MAT1 domain-containing protein. (189 aa)
	Csa_1G599390	Uncharacterized protein. (200 aa)

Your Current Organism:

Cucumis sativus

NCBI taxonomy Id: 3659
Other names: C. sativus, Cucumis sativus L., cucumber, cucumbers

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Csa_1G020880	Csa_1G024870	A0A0A0LSL9	A0A0A0LPN4	HTH TFE/IIEalpha-type domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.992
Csa_1G020880	Csa_1G043180	A0A0A0LSL9	A0A0A0LQM4	HTH TFE/IIEalpha-type domain-containing protein.	Uncharacterized protein.	0.926
Csa_1G020880	Csa_1G257890	A0A0A0LSL9	A0A0A0LTR9	HTH TFE/IIEalpha-type domain-containing protein.	Uncharacterized protein.	0.949
Csa_1G020880	Csa_1G257900	A0A0A0LSL9	A0A0A0LW26	HTH TFE/IIEalpha-type domain-containing protein.	MAT1 domain-containing protein.	0.949
Csa_1G020880	Csa_1G599390	A0A0A0LSL9	A0A0A0LWT4	HTH TFE/IIEalpha-type domain-containing protein.	Uncharacterized protein.	0.993
Csa_1G020880	Csa_2G072450	A0A0A0LSL9	A0A0A0LMM2	HTH TFE/IIEalpha-type domain-containing protein.	Uncharacterized protein.	0.993
Csa_1G020880	Csa_2G093850	A0A0A0LSL9	A0A0A0LHS1	HTH TFE/IIEalpha-type domain-containing protein.	RPOLD domain-containing protein.	0.990
Csa_1G020880	Csa_2G193330	A0A0A0LSL9	A0A0A0LKQ1	HTH TFE/IIEalpha-type domain-containing protein.	Uncharacterized protein.	0.922
Csa_1G020880	Csa_2G363560	A0A0A0LSL9	A0A0A0LRL0	HTH TFE/IIEalpha-type domain-containing protein.	Uncharacterized protein.	0.956
Csa_1G020880	Csa_2G401490	A0A0A0LSL9	A0A0A0LQ01	HTH TFE/IIEalpha-type domain-containing protein.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.972
Csa_1G020880	Csa_2G401990	A0A0A0LSL9	A0A0A0LMF8	HTH TFE/IIEalpha-type domain-containing protein.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.972
Csa_1G020880	Csa_3G002510	A0A0A0LSL9	A0A0A0L655	HTH TFE/IIEalpha-type domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.808
Csa_1G020880	Csa_3G036500	A0A0A0LSL9	A0A0A0L4F5	HTH TFE/IIEalpha-type domain-containing protein.	Uncharacterized protein.	0.986
Csa_1G020880	Csa_3G039340	A0A0A0LSL9	A0A0A0L2L4	HTH TFE/IIEalpha-type domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.808
Csa_1G020880	Csa_3G129690	A0A0A0LSL9	A0A0A0L7W2	HTH TFE/IIEalpha-type domain-containing protein.	Uncharacterized protein.	0.959
Csa_1G020880	Csa_3G143540	A0A0A0LSL9	A0A0A0L5A3	HTH TFE/IIEalpha-type domain-containing protein.	Uncharacterized protein.	0.922
Csa_1G020880	Csa_3G166240	A0A0A0LSL9	A0A0A0L816	HTH TFE/IIEalpha-type domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.991
Csa_1G020880	Csa_3G624050	A0A0A0LSL9	A0A0A0LCA6	HTH TFE/IIEalpha-type domain-containing protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.996
Csa_1G020880	Csa_3G690810	A0A0A0LSL9	A0A0A0LCD5	HTH TFE/IIEalpha-type domain-containing protein.	RNA_pol_L_2 domain-containing protein.	0.954
Csa_1G020880	Csa_3G815480	A0A0A0LSL9	A0A0A0LEN8	HTH TFE/IIEalpha-type domain-containing protein.	Uncharacterized protein.	0.913