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Smed_0169 Smed_0169 aroC aroC trpD trpD trpC trpC Smed_1570 Smed_1570 Smed_2295 Smed_2295 aroB aroB aroK aroK Smed_2684 Smed_2684 Smed_2685 Smed_2685 Smed_2686 Smed_2686 Smed_3096 Smed_3096 Smed_3176 Smed_3176 aroE aroE trpF trpF trpB trpB trpA trpA aroA aroA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Smed_0169TIGRFAM: chorismate mutase related enzymes; PFAM: Chorismate mutase; KEGG: sme:SMc02253 putative salicylate biosynthesis protein. (103 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (365 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (337 aa)
trpCPFAM: Indole-3-glycerol phosphate synthase; KEGG: sme:SMc00236 probable indole-3-glycerol phosphate synthase (IGPS) tryptophan biosynthesis lyase decarboxylase protein; Belongs to the TrpC family. (271 aa)
Smed_1570TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase class II; KEGG: sme:SMc00155 phospho-2-dehydro-3-deoxyheptonate aldolase. (457 aa)
Smed_2295Anthranilate synthase; TIGRFAM: glutamine amidotransferase of anthranilate synthase; anthranilate synthase; PFAM: glutamine amidotransferase class-I; Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein; KEGG: sme:SMc02725 anthranilate synthase includes: glutamine amidotransferase protein. (729 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (380 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (192 aa)
Smed_2684TIGRFAM: oligoendopeptidase, pepF/M3 family; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; Oligopeptidase F; KEGG: sme:SMc04012 putative oligoendopeptidase F protein. (627 aa)
Smed_2685TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: sme:SMc04013 putative para-aminobenzoate synthase component I protein. (385 aa)
Smed_2686KEGG: sme:SMc04014 4-amino-4-deoxychorismate lyase. (208 aa)
Smed_3096TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; KEGG: sme:SMc03858 putative chorismate mutase protein. (111 aa)
Smed_3176PFAM: protein of unknown function DUF993; KEGG: sme:SMc04402 hypothetical protein. (389 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (286 aa)
trpFPFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: sme:SMc02767 N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (215 aa)
trpBTryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (406 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (279 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (456 aa)
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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