STRINGSTRING
Smed_0585 Smed_0585 Smed_0718 Smed_0718 leuA leuA ilvD ilvD Smed_3425 Smed_3425
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Smed_0585PFAM: aminotransferase class IV; KEGG: sme:SMc00042 branched-chain amino acid aminotransferase. (293 aa)
Smed_0718TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: sme:SMc02546 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (538 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (576 aa)
ilvDTIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: sme:SMc04045 probable dihydroxy-acid dehydratase protein; Belongs to the IlvD/Edd family. (612 aa)
Smed_3425TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; KEGG: sme:SMc02896 branched-chain amino acid aminotransferase. (365 aa)
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.