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accD accD kdsB kdsB Smed_0022 Smed_0022 Smed_0110 Smed_0110 Smed_0112 Smed_0112 Smed_0113 Smed_0113 Smed_0132 Smed_0132 fabA fabA Smed_0144 Smed_0144 Smed_0194 Smed_0194 Smed_0422 Smed_0422 Smed_0424 Smed_0424 lpxK lpxK ispE ispE Smed_0458 Smed_0458 dxs dxs Smed_0500 Smed_0500 Smed_0512 Smed_0512 ispH ispH Smed_0568 Smed_0568 Smed_0654 Smed_0654 Smed_0655 Smed_0655 acpS acpS psd psd Smed_0724 Smed_0724 Smed_0744 Smed_0744 acpP acpP Smed_0747 Smed_0747 Smed_0772 Smed_0772 Smed_0781 Smed_0781 plsX plsX fabH fabH Smed_0854 Smed_0854 Smed_0855 Smed_0855 Smed_0871 Smed_0871 plsY plsY Smed_0952 Smed_0952 Smed_0953 Smed_0953 kdsA kdsA lipA lipA ispDF ispDF Smed_1135 Smed_1135 Smed_1136 Smed_1136 lpxD lpxD fabZ fabZ lpxA lpxA Smed_1142 Smed_1142 LpxB LpxB Smed_1155 Smed_1155 Smed_1285 Smed_1285 glmU glmU Smed_3449 Smed_3449 Smed_1420 Smed_1420 Smed_1438 Smed_1438 Smed_1557 Smed_1557 Smed_1567 Smed_1567 Smed_1578 Smed_1578 Smed_1602 Smed_1602 Smed_1614 Smed_1614 Smed_1736 Smed_1736 Smed_1738 Smed_1738 Smed_1739 Smed_1739 Smed_1740 Smed_1740 Smed_1741 Smed_1741 Smed_1810 Smed_1810 acpP-2 acpP-2 lpxC lpxC murG murG lcdH lcdH Smed_2268 Smed_2268 Smed_2269 Smed_2269 Smed_2277 Smed_2277 cysQ cysQ GldA GldA Smed_2461 Smed_2461 Smed_2521 Smed_2521 Smed_2534 Smed_2534 Smed_2546 Smed_2546 accA accA Smed_2636 Smed_2636 Smed_2692 Smed_2692 Smed_2695 Smed_2695 Smed_2701 Smed_2701 Smed_2745 Smed_2745 Smed_3520 Smed_3520 dxr dxr Smed_3448 Smed_3448 gpsA gpsA Smed_3122 Smed_3122 ispG ispG Smed_3179 Smed_3179
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (304 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (250 aa)
Smed_0022KEGG: sme:SMc01133 hypothetical protein. (114 aa)
Smed_0110PFAM: AMP-dependent synthetase and ligase; KEGG: sme:SMc02162 acyl-CoA synthase. (566 aa)
Smed_0112PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sme:SMc02159 hypothetical protein. (221 aa)
Smed_0113PFAM: phospholipid/glycerol acyltransferase; KEGG: sme:SMc02158 putative acyltransferase protein. (203 aa)
Smed_0132PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sme:SMc02134 hypothetical protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (205 aa)
fabABeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (171 aa)
Smed_0144PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: sme:SMc02227 putative fatty oxidation complex alpha subunit includes: enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, 3-hydroxybutyryl-CoA epimerase transmembrane protein. (736 aa)
Smed_0194PFAM: sulfatase; KEGG: sme:SMc02270 capsular polysaccharide biosynthesis/export transmembrane protein. (530 aa)
Smed_0422PFAM: inositol monophosphatase; KEGG: sme:SMc00896 putative sulfite biosynthesis protein. (272 aa)
Smed_0424Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (439 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (346 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (303 aa)
Smed_0458PFAM: Polyprenyl synthetase; KEGG: sme:SMc00860 putative octaprenyl-diphosphate synthase protein; Belongs to the FPP/GGPP synthase family. (338 aa)
dxsDeoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (637 aa)
Smed_0500PFAM: AMP-dependent synthetase and ligase; KEGG: sme:SMc00965 hypothetical protein. (498 aa)
Smed_0512PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sme:SMc00005 putative enoyl-acyl-carrier-protein reductase NADH. (272 aa)
ispHHydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (336 aa)
Smed_0568TIGRFAM: Quinone oxidoreductase putative PIG3; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMc00034 putative oxidoreductase protein. (333 aa)
Smed_0654PFAM: diacylglycerol kinase catalytic region; KEGG: sme:SMc02382 hypothetical protein. (308 aa)
Smed_0655PFAM: glycosyl transferase family 39; KEGG: sme:SMc02383 hypothetical protein. (493 aa)
acpSHolo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (139 aa)
psdPhosphatidylserine decarboxylase related protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (232 aa)
Smed_0724TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sme:SMc00552 putative CDP-diacylglycerol--serine O-phosphatidyltransferase transmembrane protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (295 aa)
Smed_0744TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: sme:SMc00571 acyl-carrier-protein S-malonyltransferase. (314 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa)
Smed_0747Beta-ketoacyl synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (421 aa)
Smed_0772PFAM: AMP-dependent synthetase and ligase; KEGG: sme:SMc00592 hypothetical, transmembrane protein. (887 aa)
Smed_0781TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sme:SMc00601 probable CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase transmembrane protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (195 aa)
plsXFatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (347 aa)
fabH3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (323 aa)
Smed_0854TIGRFAM: exopolysaccharide transport protein family; PFAM: lipopolysaccharide biosynthesis protein; KEGG: sme:SMc01795 putative polysaccharide synthesis/transport transmembrane protein. (709 aa)
Smed_0855KEGG: sme:SMc01796 hypothetical protein. (416 aa)
Smed_0871PFAM: phospholipase D/Transphosphatidylase; KEGG: sme:SMc04448 hypothetical protein. (520 aa)
plsYProtein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (203 aa)
Smed_0952acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
Smed_0953acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (158 aa)
kdsATIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: sme:SMc01027 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase). (279 aa)
lipALipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (323 aa)
ispDF2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (404 aa)
Smed_1135Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (252 aa)
Smed_1136PFAM: phosphatidate cytidylyltransferase; KEGG: sme:SMc02096 probable phosphatidate cytidylyltransferase transmembrane protein; Belongs to the CDS family. (277 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (354 aa)
fabZBeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (154 aa)
lpxAacyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (270 aa)
Smed_1142PFAM: protein of unknown function DUF1009; KEGG: sme:SMc02090 hypothetical protein. (295 aa)
LpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (399 aa)
Smed_1155PFAM: phospholipase D/Transphosphatidylase; KEGG: sme:SMc02076 putative cardiolipin synthetase transmembrane protein. (487 aa)
Smed_1285PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: sme:SMa0257 probable methylamine. (697 aa)
glmUNucleotidyl transferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (456 aa)
Smed_3449PFAM: Beta-ketoacyl synthase; KEGG: sme:SMc00327 probable 3-oxoacyl-acyl-carrier-protein synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (406 aa)
Smed_1420Phosphatidylcholine synthase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (241 aa)
Smed_1438PFAM: AMP-dependent synthetase and ligase; KEGG: sme:SMc00261 acyl-CoA synthase. (549 aa)
Smed_1557PFAM: metallophosphoesterase; KEGG: sme:SMc00171 hypothetical protein. (277 aa)
Smed_1567PFAM: sulfatase; KEGG: sme:SMc00195 cyclic beta-1,2-glucan modification transmembrane protein. (645 aa)
Smed_1578KEGG: sme:SMc00147 hypothetical protein. (305 aa)
Smed_1602Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (160 aa)
Smed_1614PFAM: thioesterase superfamily protein; KEGG: sme:SMc04228 putative acyl-CoA thioester hydrolase. (129 aa)
Smed_1736PFAM: lipid A biosynthesis acyltransferase; KEGG: sme:SMc04268 putative lipid A biosynthesis KDO2-lauroyl-lipid IVA acyltransferase protein. (307 aa)
Smed_1738PFAM: Beta-ketoacyl synthase; KEGG: sme:SMc04273 putative 3-oxoacyl-acyl-carrier-protein synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (427 aa)
Smed_1739PFAM: Beta-ketoacyl synthase; KEGG: sme:SMc04275 3-oxoacyl-(acyl carrier protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (400 aa)
Smed_1740PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: sme:SMc04277 putative (3R)-hydroxymyristoyl-[acyl carrier] dehydratase transmembrane protein. (158 aa)
Smed_1741PFAM: phosphopantetheine-binding; KEGG: sme:SMc04278 probable acyl carrier protein. (95 aa)
Smed_1810KEGG: gvi:gll2178 hypothetical protein. (183 aa)
acpP-2Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (83 aa)
lpxCUDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (317 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (374 aa)
lcdH3-hydroxyacyl-CoA dehydrogenase NAD-binding; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine. (496 aa)
Smed_2268PFAM: MaoC domain protein dehydratase; KEGG: sme:SMc02696 hypothetical protein. (151 aa)
Smed_2269PFAM: MaoC domain protein dehydratase; KEGG: sme:SMc02697 hypothetical protein. (156 aa)
Smed_2277TIGRFAM: conserved hypothetical membrane protein; KEGG: sme:SMc02705 hypothetical protein. (937 aa)
cysQ3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (258 aa)
GldAPFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase; KEGG: sme:SMc02038 glycerol dehydrogenase. (364 aa)
Smed_2461PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sme:SMc02039 putative oxidoreductase protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (242 aa)
Smed_2521KEGG: sme:SMc00742 hypothetical protein. (424 aa)
Smed_2534PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: sme:SMc00727 3-hydroxybutyryl-CoA dehydrogenase. (290 aa)
Smed_2546PFAM: phospholipid/glycerol acyltransferase; KEGG: sme:SMc00714 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase (PlsC) protein. (259 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
Smed_2636PFAM: metallophosphoesterase; KEGG: sme:SMc03964 hypothetical transmembrane protein. (300 aa)
Smed_2692PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: ret:RHE_PA00028 putative glycerol-3-phosphate dehydrogenase (NAD(P)+) protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (338 aa)
Smed_2695PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ret:RHE_PA00025 probable oxidoreductase protein, short-chain dehydrogenase-reductase family. (241 aa)
Smed_2701PFAM: 3-dehydroquinate synthase; KEGG: ret:RHE_PA00022 putative glycerol 1-phosphate dehydrogenase protein (L-arabinose utilization protein) protein. (451 aa)
Smed_2745PFAM: MaoC domain protein dehydratase; KEGG: sme:SMc03927 putative nodulation protein. (162 aa)
Smed_3520PFAM: TspO/MBR family protein; KEGG: atc:AGR_C_485 mitochondrial benzodiazepine receptor/sensory transduction protein. (177 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (391 aa)
Smed_3448PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sme:SMc00326 putative enoyl-acyl-carrier-protein reductase NADH. (268 aa)
gpsAPFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: sme:SMc03229 probable glycerol-3-phosphate dehydrogenase protein. (331 aa)
Smed_3122PFAM: Polyprenyl synthetase; KEGG: sme:SMc03884 probable geranyltranstransferase protein; Belongs to the FPP/GGPP synthase family. (304 aa)
ispG1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (417 aa)
Smed_3179PFAM: phosphoesterase PA-phosphatase related; KEGG: sme:SMc04406 hypothetical protein. (230 aa)
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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