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Smed_2807 Smed_2807 Smed_2811 Smed_2811 atpC atpC atpD atpD atpG atpG atpA atpA atpH atpH Smed_3051 Smed_3051 ccmA ccmA Smed_3284 Smed_3284 Smed_3462 Smed_3462 Smed_2806 Smed_2806 Smed_2775 Smed_2775 Smed_2774 Smed_2774 Smed_2759 Smed_2759 Smed_2757 Smed_2757 Smed_2428 Smed_2428 Smed_2427 Smed_2427 Smed_2426 Smed_2426 Smed_2425 Smed_2425 Smed_2408 Smed_2408 Smed_2322 Smed_2322 Smed_2192 Smed_2192 Smed_2188 Smed_2188 fbpC fbpC Smed_2140 Smed_2140 Smed_2137 Smed_2137 Smed_1842 Smed_1842 potA-2 potA-2 znuC znuC Smed_1556 Smed_1556 Smed_1541 Smed_1541 Smed_1540 Smed_1540 Smed_1406 Smed_1406 Smed_1374 Smed_1374 Smed_1163 Smed_1163 TrkA TrkA Smed_1033 Smed_1033 hppA hppA Smed_0798 Smed_0798 Smed_0613 Smed_0613 Smed_0612 Smed_0612 Smed_0609 Smed_0609 Smed_0607 Smed_0607 Smed_0523 Smed_0523 Smed_0519 Smed_0519 Smed_0518 Smed_0518 atpF1 atpF1 atpF2 atpF2 atpE atpE atpB atpB kup1 kup1 potA potA FliI FliI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Smed_2807TIGRFAM: multicomponent Na+/H+ antiporter, subunit 3; PFAM: NADH-ubiquinone oxidoreductase chain 4L; KEGG: sme:SMc03180 multicomponent K+:H+ antiporter subunit C. (115 aa)
Smed_2811TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+ antiporter subunit; KEGG: sme:SMc03184 PH adaptation potassium efflux system G transmembrane protein. (123 aa)
atpCATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (134 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (509 aa)
atpGATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (291 aa)
atpAATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (509 aa)
atpHATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (188 aa)
Smed_3051TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: sme:SMc03807 probable ammonium transporter protein. (451 aa)
ccmAHeme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (207 aa)
Smed_3284PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: bmb:BruAb2_0512 ABC transporter, ATP-binding protein; Belongs to the ABC transporter superfamily. (350 aa)
Smed_3462Putative adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; histidine kinase HAMP region domain protein; KEGG: sme:SMc00339 adenylate cyclase 1 protein. (651 aa)
Smed_2806TIGRFAM: monovalent cation/H+ antiporter, subunit 2; monovalent cation/H+ antiporter, subunit 1; PFAM: NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I); Na+ antiporter MnhB subunit-related protein; KEGG: sme:SMc03179 multicomponent K+:H+ antiporter subunit A. (997 aa)
Smed_2775PFAM: high-affinity nickel-transporter; KEGG: sme:SMc02986 hypothetical protein; Belongs to the NiCoT transporter (TC 2.A.52) family. (337 aa)
Smed_2774PFAM: protein of unknown function DUF1007; KEGG: sme:SMc02985 hypothetical protein. (214 aa)
Smed_2759PFAM: alanine dehydrogenase/PNT domain protein; KEGG: sme:SMc03950 probable proton-translocating nicotinamide nucleotide transhydrogenase subunit protein. (382 aa)
Smed_2757NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (467 aa)
Smed_2428PFAM: cytochrome c oxidase subunit III; KEGG: sme:SMc01985 cytochrome c oxidase subunit III. (240 aa)
Smed_2427PFAM: cytochrome c oxidase subunit III; KEGG: sme:SMc01984 cytochrome c oxidase subunit III. (232 aa)
Smed_2426Cytochrome c oxidase subunit I type; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (592 aa)
Smed_2425PFAM: cytochrome c oxidase subunit II; KEGG: sme:SMc01982 cytochrome c oxidase subunit II. (314 aa)
Smed_2408TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc01965 putative spermidine/putrescine transport ATP-binding ABC transporter protein. (345 aa)
Smed_2322PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc01529 putative dipeptide transport ATP-binding ABC transporter protein. (255 aa)
Smed_2192TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: sme:SMc01657 putative ferrichrome-iron receptor precursor protein. (724 aa)
Smed_2188PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc01653 putative ATP-binding ABC transporter protein; Belongs to the ABC transporter superfamily. (331 aa)
fbpCSpermidine/putrescine ABC transporter ATPase subunit; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system. (359 aa)
Smed_2140TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: sme:SMc01611 putative ferrichrome-iron receptor precursor protein. (740 aa)
Smed_2137PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc01608 putative ATP-binding ABC transporter protein; Belongs to the ABC transporter superfamily. (353 aa)
Smed_1842KEGG: sme:SMc04190 conserved hypothetical signal peptide protein. (150 aa)
potA-2Spermidine/putrescine ABC transporter ATPase subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (355 aa)
znuCABC transporter related; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (301 aa)
Smed_1556PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc00172 putative transport protein transmembrane. (407 aa)
Smed_1541Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (192 aa)
Smed_1540Cytochrome b/b6 domain; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (426 aa)
Smed_1406TIGRFAM: sodium-dependent inorganic phosphate (Pi) transporter; PFAM: Na+cotransporter; KEGG: sme:SMc00233 putative phosphate:Na+ symporter, PNaS family. (548 aa)
Smed_1374Cation transporter; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family. (484 aa)
Smed_1163PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02068 putative ABC transporter ATP-binding protein; Belongs to the ABC transporter superfamily. (372 aa)
TrkAPFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: sme:SMc01046 probable TRK system potassium uptake protein. (458 aa)
Smed_1033Magnesium transporter; Acts as a magnesium transporter. (473 aa)
hppAV-type H(+)-translocating pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. (711 aa)
Smed_0798Putative adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sme:SMc00621 adenylate cyclase 2 protein. (360 aa)
Smed_0613TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+ antiporter subunit; KEGG: sme:SMc00057 putative cation efflux system protein. (116 aa)
Smed_0612PFAM: multiple resistance and pH regulation protein F; KEGG: sme:SMc00056 putative cation efflux system protein. (128 aa)
Smed_0609PFAM: NADH-ubiquinone oxidoreductase chain 4L; KEGG: sme:SMc00053 putative cation efflux system protein. (125 aa)
Smed_0607NADH dehydrogenase (quinone); PFAM: NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I); KEGG: sme:SMc00051 putative cation efflux system protein. (791 aa)
Smed_0523PFAM: cytochrome c oxidase subunit III; KEGG: sme:SMc00013 cytochrome c oxidase subunit III. (292 aa)
Smed_0519Cytochrome c oxidase subunit I type; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (562 aa)
Smed_0518Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). (294 aa)
atpF1ATP synthase F0, B subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (161 aa)
atpF2H+transporting two-sector ATPase B/B' subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). (204 aa)
atpEH+transporting two-sector ATPase C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (75 aa)
atpBATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (250 aa)
kup1K potassium transporter; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family. (630 aa)
potASpermidine/putrescine ABC transporter ATPase subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (380 aa)
FliITIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; SMART: AAA ATPase; KEGG: sme:SMc03025 flagellum-specific ATP synthase protein. (467 aa)
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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