(12 nodes) RNA polymerase sigma factor, region 3/4-like network (Sinorhizobium medicae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	Smed_2284	RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc02713 putative RNA polymerase sigma-E factor (sigma-24) protein; Belongs to the sigma-70 factor family. ECF subfamily. (189 aa)
	Smed_2347	RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMc01504 two-component response regulator. (264 aa)
	Smed_2359	Transcriptional regulator, DeoR family; PFAM: putative sugar-binding domain protein; KEGG: sme:SMc01495 probable transcription regulator protein. (317 aa)
	rpoH	RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (301 aa)
	Smed_2730	RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc04051 putative RNA polymerase sigma-E factor (sigma-24) protein; Belongs to the sigma-70 factor family. ECF subfamily. (174 aa)
	Smed_2858	Transcriptional regulator, DeoR family; PFAM: putative sugar-binding domain protein; KEGG: sme:SMc03123 putative transcriptional regulator protein. (310 aa)
	RpoH2	RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (288 aa)
	rpoD	RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (684 aa)
	Smed_1997	RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc01419 probable RNA polymerase sigma factor protein; Belongs to the sigma-70 factor family. ECF subfamily. (184 aa)
	Smed_0337	RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMc00794 two-component response regulator. (265 aa)
	Smed_0004	Putative RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc01150 putative RNA polymerase sigma-70 factor, ECF subfamily. (427 aa)
	Smed_2345	RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc01506 putative RNA polymerase sigma-E factor (sigma-24) protein; Belongs to the sigma-70 factor family. ECF subfamily. (184 aa)

Your Current Organism:

Sinorhizobium medicae

NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RpoH2	rpoD	Smed_3111	Smed_2223	RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.450
Smed_0337	Smed_1997	Smed_0337	Smed_1997	RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMc00794 two-component response regulator.	RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc01419 probable RNA polymerase sigma factor protein; Belongs to the sigma-70 factor family. ECF subfamily.	0.595
Smed_0337	Smed_2345	Smed_0337	Smed_2345	RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMc00794 two-component response regulator.	RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc01506 putative RNA polymerase sigma-E factor (sigma-24) protein; Belongs to the sigma-70 factor family. ECF subfamily.	0.783
Smed_0337	Smed_2730	Smed_0337	Smed_2730	RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMc00794 two-component response regulator.	RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc04051 putative RNA polymerase sigma-E factor (sigma-24) protein; Belongs to the sigma-70 factor family. ECF subfamily.	0.499
Smed_1997	Smed_0337	Smed_1997	Smed_0337	RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc01419 probable RNA polymerase sigma factor protein; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMc00794 two-component response regulator.	0.595
Smed_1997	Smed_2347	Smed_1997	Smed_2347	RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc01419 probable RNA polymerase sigma factor protein; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMc01504 two-component response regulator.	0.573
Smed_2345	Smed_0337	Smed_2345	Smed_0337	RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc01506 putative RNA polymerase sigma-E factor (sigma-24) protein; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMc00794 two-component response regulator.	0.783
Smed_2345	Smed_2347	Smed_2345	Smed_2347	RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc01506 putative RNA polymerase sigma-E factor (sigma-24) protein; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMc01504 two-component response regulator.	0.896
Smed_2347	Smed_1997	Smed_2347	Smed_1997	RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMc01504 two-component response regulator.	RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc01419 probable RNA polymerase sigma factor protein; Belongs to the sigma-70 factor family. ECF subfamily.	0.573
Smed_2347	Smed_2345	Smed_2347	Smed_2345	RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMc01504 two-component response regulator.	RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc01506 putative RNA polymerase sigma-E factor (sigma-24) protein; Belongs to the sigma-70 factor family. ECF subfamily.	0.896
Smed_2347	Smed_2730	Smed_2347	Smed_2730	RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMc01504 two-component response regulator.	RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc04051 putative RNA polymerase sigma-E factor (sigma-24) protein; Belongs to the sigma-70 factor family. ECF subfamily.	0.497
Smed_2730	Smed_0337	Smed_2730	Smed_0337	RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc04051 putative RNA polymerase sigma-E factor (sigma-24) protein; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMc00794 two-component response regulator.	0.499
Smed_2730	Smed_2347	Smed_2730	Smed_2347	RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: sme:SMc04051 putative RNA polymerase sigma-E factor (sigma-24) protein; Belongs to the sigma-70 factor family. ECF subfamily.	RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: response regulator receiver; Sigma-70 region 4 type 2; KEGG: sme:SMc01504 two-component response regulator.	0.497
rpoD	RpoH2	Smed_2223	Smed_3111	RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.450
rpoD	rpoH	Smed_2223	Smed_2614	RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.	0.514
rpoH	rpoD	Smed_2614	Smed_2223	RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.	RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.514